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Fluoxetine

Medication SSRI antidepressant mental health
Aka: Prozac
Brands seen in Singapore: Proctin, Fluxil, Magrilan
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for depression, ocd, bulimia or anxiety
When to take
NHS: once a day, at the SAMe time each day
Take with
Water · HealthHub: with or after food
Pros & cons
Pros
  • NHS: usually once a day
  • NHS: also prescribed for children aged 5 and over
  • NHS: comes as tablets, capsules or liquid
Cons
  • NHS: nausea, headache, diarrhoea, sleep problems
  • NHS: sexual problems and weight changes are common
  • HealthHub: under-25s — mood or behaviour may worsen
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered offline) · read 2026-08-27
    what it says
    “All 6 registered fluoxetine products carry Forensicclassification 'Prescription Only' — SIN11954P PROCTIN CAPSULE 20 mg · SIN12576P FLUXIL CAPSULE 20 mg · SIN05766P MAGRILAN CAPSULE 20 mg · SIN09317P APO-FLUOXETINE 10 mg. No PROZAC row exists.”
  2. NHS Medicines A-Z — Fluoxetine: what fluoxetine is for · read 2026-08-27
    what it says
    “Fluoxetine can be used to treat mental health conditions such as: depression; obsessive compulsive disorder (OCD); bulimia. It can sometimes be used for menopause symptoms. Fluoxetine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI).”
  3. NHS Medicines A-Z — Fluoxetine: how to take fluoxetine · read 2026-08-27
    what it says
    “Fluoxetine comes as tablets, capsules or liquid that you swallow … You usually take fluoxetine once a day … take it at the same time each day … you can take it with or without food”
  4. NHS Medicines A-Z — Fluoxetine: side effects · read 2026-08-27
    what it says
    “Common side effects of fluoxetine include: headaches; feeling sick (nausea) … diarrhoea or constipation; weight changes; sexual problems, such as low sex drive … problems sleeping … Possible serious side effects … serotonin syndrome … unexplained bruising or bleeding”
  5. NHS Medicines A-Z — Fluoxetine: who can and cannot take it · read 2026-08-27
    what it says
    “sometimes used to treat depression in children aged 5 years or older … it may not be suitable if: … diabetes … epilepsy … heart disease … glaucoma … a bleeding disorder … you've ever had mania”
  6. NHS Medicines A-Z — Fluoxetine: taking it with other medicines, food and drink · read 2026-08-27
    what it says
    “antidepressants called monoamine oxidase inhibitors (MAOIs), such as moclobemide and selegiline; metoprolol … tamoxifen … anticoagulants, such as warfarin and apixaban; NSAIDs, such as aspirin and ibuprofen … Do not use the herbal supplement St John's wort”
  7. HealthHub (National Medication Information workgroup, SG) — Fluoxetine: what is this medication for · read 2026-08-27
    what it says
    “Fluoxetine belongs to a class of medications known as Selective Serotonin Reuptake Inhibitors (SSRI). It is used to treat symptoms of depression … symptoms of anxiety … obsessive-compulsive disorders, eating disorders and other conditions.”
  8. HealthHub — Fluoxetine: how should I take or use this medication · read 2026-08-27
    what it says
    “Fluoxetine should be taken with or after food … needs to be taken regularly for a few weeks before you can feel its full benefits … unpleasant effects … if you suddenly stop taking the medication on your own.”
  9. HealthHub — Fluoxetine: precautions and the under-25 warning · read 2026-08-27
    what it says
    “The following changes have been observed in some patients particularly below the age of 25 years taking this medication: New or worsening thoughts of harming yourself or ending your life; Worsening agitation, restlessness, violent behaviour”
  10. US FDA label for PROZAC (fluoxetine), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2026-01-08) · read 2026-08-27
    what it says
    “Administer doses above 20 mg/day once daily in the morning or twice daily (i.e., morning and noon). The maximum fluoxetine dose should not exceed 80 mg/day.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.