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Fluconazole

Medication azole antifungal (oral) antibioticother
Aka: Diflucan, Canesten Oral
Brands seen in Singapore: Diflucan, Medoflucon, Apo-Fluconazole, Omastin, Fungby
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for thrush and other candida infections
When to take
Usually once a day · vaginal thrush is a single dose
Take with
Water · capsules and liquid work with or without food
Pros & cons
Pros
  • Vaginal thrush is one 150 mg dose per NHS
  • Thrush symptoms usually settle within 7 days (NHS)
  • Food optional — with or without a meal (NHS)
Cons
  • Nausea and diarrhoea are the most common effects
  • Rare but serious liver injury is a label warning
  • Prescription-only in SG though otc in the UK
Sources
  1. HSA — Listing of Registered Therapeutic Products (official open dataset on data.gov.sg; full 5,511-row register pulled via the datastore_search API) · read 2026-08-27
    what it says
    “Forensicclassification = "Prescription Only" for all 10 fluconazole products on the register (7 oral capsules, 3 intravenous) — SIN06804P/SIN04460P DIFLUCAN CAPSULE, SIN12599P MEDOFLUCON 150, SIN13329P Apo-Fluconazole 150mg, SIN13067P OMASTIN, SIN17396P FUNGBY. No Pharmacy Only row.”
  2. NHS Medicines A–Z — About fluconazole (brand names: Azocan, Diflucan, Canesten Thrush Oral Capsules) · read 2026-08-27
    what it says
    “Fluconazole is an antifungal medicine … available on prescription. You can also buy it from a pharmacy for vaginal thrush or balanitis … symptoms should be better within 7 days … feeling sick (nausea) and diarrhoea.”
  3. NHS Medicines A–Z — How and when to take fluconazole · read 2026-08-27
    what it says
    “vaginal thrush or balanitis – 150mg, taken as a single dose · oral (mouth) thrush – 50mg a day … candida infections … 200mg to 800mg a day … You can take fluconazole capsules and liquid with or without food.”
  4. FDA DailyMed — Fluconazole tablets, Dosage and Administration and Warnings (NuCare Pharmaceuticals), SPL effective 17 Nov 2025; via the openFDA drug label API · read 2026-08-27
    what it says
    “vaginal candidiasis is 150 mg as a single oral dose … Doses up to 400 mg/day may be used … Absolute doses exceeding 600 mg/day are not recommended … rare cases of serious hepatic toxicity, including fatalities.”
  5. FDA DailyMed — Fluconazole tablets, Contraindications and Precautions/Drug Interactions (NuCare Pharmaceuticals), SPL effective 17 Nov 2025 · read 2026-08-27
    what it says
    “Coadministration of other drugs known to prolong the QT interval … such as erythromycin, pimozide, and quinidine are contraindicated … Prothrombin time may be increased … coumarin-type anticoagulants … hypoglycemia … glyburide … myopathy and rhabdomyolysis … atorvastatin and simvastatin.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.