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Fenofibrate

Medication fibrate heart & blood pressure
Aka: Lipanthyl
Brands seen in Singapore: Lipanthyl, Fenosup Lidose, Fenogal Lidose, AA-Feno Micro, Trolip
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed to lower triglycerides and LDL cholesterol
When to take
HealthHub: with or after food for most formulations
Take with
Food · HealthHub: lipanthyl penta 145 with or without
Pros & cons
Pros
  • HealthHub: raises HDL while lowering LDL and fat
  • FDA: one 160 mg tablet a day at the stated maximum
  • HealthHub: may reduce risk of heart attack and stroke
Cons
  • FDA: serious liver injury reported; enzymes monitored
  • FDA: muscle damage risk rises alongside a statin
  • FDA: more cholesterol into bile — gallstone risk
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 15 rows containing fenofibrate read Forensicclassification 'Prescription Only' — Lipanthyl Penta 145mg and Supra 160mg, Fenosup Lidose 160mg, Fenogal Lidose 200mg, AA-Feno Micro 200mg, Trolip 100/300mg, Trolate 100/300mg, Tricor 160mg, EP-Feno 145mg; ATC C10AB05.”
  2. HealthHub (Pharmaceutical Society of Singapore) — Fenofibrate: what is this medication for · read 2026-08-27
    what it says
    “They lower the amount of 'fat' (triglyceride) and 'bad cholesterol' … as well as increase … 'good cholesterol' … fibrates may reduce your risk for heart attack and stroke.”
  3. HealthHub — Fenofibrate: how should I take this medication · read 2026-08-27
    what it says
    “This medicine should be taken with or after food. However, for special formulations of fenofibrate (e.g. Lipanthyl Penta 145, Trilipix 135, Trilipix 45), you may take this medication with or without food … Swallow the tablet/capsule whole.”
  4. HealthHub — Fenofibrate: what precautions should I take · read 2026-08-27
    what it says
    “You have liver, kidney or gallbladder problems. You have an underactive thyroid gland. You have had a history of pancreatitis … You are pregnant, planning to become pregnant, or breastfeeding.”
  5. HealthHub — Fenofibrate: what food or medication should I avoid · read 2026-08-27
    what it says
    “Medications for cholesterol-lowering (e.g. cholestyramine, colestipol, statins, ezetimibe); Medications used to suppress immune system (e.g. cyclosporine, tacrolimus); Warfarin, a type of blood-thinner”
  6. US FDA label — fenofibrate tablets, section 2 Dosage and Administration, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Primary hypercholesterolemia or mixed dyslipidemia: Initial dose of 160 mg once daily. Severe hypertriglyceridemia: Initial dose of 54 to 160 mg once daily. Maximum dose is 160 mg … Should be given with meals.”
  7. US FDA label — fenofibrate tablets, section 4 Contraindications, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Severe renal dysfunction, including dialysis patients. Active liver disease. Gallbladder disease. Known hypersensitivity to fenofibrate. Nursing mothers.”
  8. US FDA label — fenofibrate tablets, section 5 Warnings and Precautions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Hepatotoxicity: Serious drug-induced liver injury, including liver transplantation and death, has been reported … Myopathy and rhabdomyolysis … Risks are increased during co-administration with a statin … Cholelithiasis: Fenofibrate increases cholesterol excretion into the bile”
  9. US FDA label — fenofibrate tablets, section 7 Drug Interactions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Potentiation of coumarin-type anticoagulant effects has been observed with prolongation of the PT/INR … Immunosuppressants such as cyclosporine and tacrolimus can produce nephrotoxicity … Cases of myopathy, including rhabdomyolysis, have been reported with fenofibrates co administered with colchicine”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.