Fadogia agrestis
Supplement
botanical
men's healthfitness
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Rat sexual-behaviour and testosterone studies only
Pros & cons
Pros
- Rat studies report higher serum testosterone
- The SAMe rat study reports more frequent mating
Cons
- No human trial appears in the sources read
- 28 days at 50–100 mg/kg harmed rat testes
- SG bars sexual-dysfunction claims (table 6)
Sources
- Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats (Yakubu et al., Asian Journal of Andrology 2005) — abstract via Europe PMC · read 2026-08-27
what it says
“Male rats were orally dosed with 18 mg/kg, 50 mg/kg and 100 mg/kg body weight … There was also a significant increase in serum testosterone concentrations in all the groups in a manner suggestive of dose-dependence”
- Effects of oral administration of aqueous extract of Fadogia agrestis stem on some testicular function indices of male rats (Yakubu et al., Journal of Ethnopharmacology 2008) — abstract via Europe PMC · read 2026-08-27
what it says
“The alterations brought about by the aqueous extract of Fadogia agrestis stem are indications of adverse effects on the male rat testicular function and this may adversely affect the functional capacities of the testes.”
- A review on plants used for improvement of sexual performance and virility (Chauhan et al., BioMed Research International 2014) — Table 2 row 32 · read 2026-08-27
what it says
“Fadogia agrestis Schweinf. Ex Hiern (Rubiaceae) Stem Alkaloids and Saponins Increased the blood testosterone concentrations”
- HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (October 2025), Annex A (118 rows) and Annex B (4 rows) — fadogia agrestis is NOT LISTED in either annex; Annex A runs 46. Excoecaria agallocha then 47. Folic acid where a 'Fadogia' row would fall · read 2026-08-27
what it says
“The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
- HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. No. 020 (January 2026), clause 4.8 with Tables 4–5 (vitamins and minerals only — no botanical rows) · read 2026-08-27
what it says
“4.8 HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
- HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. No. 020 (January 2026), clause 6.6 and Table 6 (diseases/conditions not allowed for health supplements), reproductive-system row · read 2026-08-27
what it says
“HS must not be labelled, advertised or promoted for any specific medicinal purpose … Reproductive system: Menstrual disorders, sexual dysfunction, infertility, frigidity, impotency, conception, pregnancy”
- iHerb Singapore — Fadogia Agrestis category page, default listing order · read 2026-08-27
what it says
“1 - 11 of 11 results: EVLution Nutrition, Tongkat Ali + Fadogia Agrestis; EVLution Nutrition, Fadogia Agrestis 600 mg; Nutricost, Fadogia Agrestis 600 mg; Toniiq, Tongkat Ali + Fadogia; ALLMAX, Essentials Fadogia Agrestis 325 mg; Vitamatic, Fadogia Agrestis”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.