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Eyebright

Supplement botanical general nutrition
Aka: Euphrasia officinalis
Brands seen in Singapore: Nature's Way, Nature's Answer, Christopher's Original Formulas, Swanson Vitamins
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
The human studies are eye drops, not oral capsules
Pros & cons
Pros
  • 84 preterm babies: a placebo-controlled eye-drop RCT
  • 65-patient cohort: 81.5% complete recovery reported
  • No serious adverse events in either eye-drop study
Cons
  • The RCT missed its endpoint: 55.0% vs 51.2% placebo
  • The cohort was open-label with no control arm
  • No oral eyebright trial was found at all
Sources
  1. Euphrasia Eye Drops in Preterm Neonates With Ocular Discharge: A Randomized Double-Blind Placebo-Controlled Trial (Meier-Girard D et al.; Front Pediatr 2020; PMID 32850558) · read 2026-08-27
    what it says
    “Euphrasia or placebo was administrated at a dose of one drop in each eye four times a day over a period of 96 h … 22 (55.0%) achieved our primary outcome compared to 21 (51.2%) in the placebo arm”
  2. Prospective cohort trial of Euphrasia single-dose eye drops in conjunctivitis (Stoss M, Michels C, Peter E, Beutke R, Gorter RW; J Altern Complement Med 2000; PMID 11152054) · read 2026-08-27
    what it says
    “A complete recovery was seen in 53 patients (81.5%) … No serious adverse events were observed … A dosage of one drop three times a day seems to be the general prescribed dosage.”
  3. HSA Singapore — Health Supplements Guidelines (January 2026), Table 6: Examples of Diseases/Conditions/Disorders Not Allowed for Health Supplements · read 2026-08-27
    what it says
    “Eyes and ears — Blindness, cataract, deafness … Others — Cancers, infectious diseases, inflammatory conditions or diseases”
  4. HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines (Oct 2025), Annex A (118 rows, Abrus to Zinc) and Annex B (4 rows) — both searched, no row for this ingredient · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  5. HSA Singapore — Health Supplements Guidelines (January 2026), clause 4.8 and Tables 4–5 (vitamins and minerals only) · read 2026-08-27
    what it says
    “HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
  6. iHerb Singapore — Eyebright category page, default order (1 - 7 of 7 results); the 7 listings carry only 4 distinct brands: Nature's Way, Nature's Answer, Christopher's Original Formulas, Swanson Vitamins · read 2026-08-27
    what it says
    “Nature's Way, Eyebright Herb, 100 Vegan Capsules … Nature's Answer, Eyebright Herb, Fluid Extract, Alcohol-Free … Christopher's Original Formulas, Herbal Eye Formula … Swanson Vitamins, Bilberry Eyebright Vision Complex”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.