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Eleuthero

Supplement botanical energy
Aka: Siberian ginseng, Eleutherococcus senticosus
Brands seen in Singapore: California Gold Nutrition, NOW Foods, Imperial Elixir, Swanson Vitamins, Nature's Answer
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Fatigue and weakness — an ema traditional-use approval
Studied for
One 8-week study used 120 mg a day of root extract
Pros & cons
Pros
  • Ema approved it for symptoms of asthenia in 2014
  • A who monograph cites less exhaustion and tiredness
Cons
  • Approval rests on long use, not trial evidence
  • Trials are heterogeneous and low quality
  • Products vary; one case traced to a toxic substitute
Sources
  1. Eleutherococcus root: phytochemistry and pharmacological potential as an adaptogen (Front Pharmacol 2025) · read 2026-08-27
    what it says
    “The European Medicines Agency (EMA) approved E. senticosus root in 2014 for the treatment of symptoms of asthenia … classified as a traditional herbal medicine entirely based on its long-standing use … the lack of robust clinical evidence”
  2. Eleutherococcus root — clinical dose, blood pressure and product-identity findings (Front Pharmacol 2025) · read 2026-08-27
    what it says
    “compare the effect of 120 mg/day of E. senticosus root extract … an increase in blood pressure was also observed in some people with hypertension … a case of neonatal androgenization associated with maternal eleuthero use”
  3. HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines (Oct 2025, GL-CHPB-1-012) · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  4. HSA — Health Supplements Guidelines (Jan 2026, GL-CHPB-3-001 Rev. 020), Tables 4–5 · read 2026-08-27
    what it says
    “HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
  5. iHerb Singapore — category listing (default order) · read 2026-08-27
    what it says
    “Eleuthero”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.