DMAE
Supplement
specialty compound
brain & mood
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Marketed for focus — a choline precursor, evidence is thin
Pros & cons
Pros
- Acts as a choline precursor for acetylcholine
- Not named in HSA's prohibited or restricted annexes
Cons
- 'suggested' 500–2000 mg rests on old, weak data
- Reviews flag uncertainty about real cognitive gains
- No RDA, no upper limit, no SG cap set
Sources
- Focus on Cognitive Enhancement: A Narrative Overview of Nootropics and "Smart Drug" Use and Misuse (Biology 2025) · read 2026-08-27
what it says
“deanol (DMAE) and meclofenoxate serve as choline precursors, supporting acetylcholine synthesis and potentially improving learning and memory, with suggested daily intakes ranging from 500 to 2000 mg”
- Focus on Cognitive Enhancement: A Narrative Overview of Nootropics and "Smart Drug" Use and Misuse (Biology 2025) — abstract · read 2026-08-27
what it says
“there are relevant levels of uncertainty in terms of smart drugs' effectiveness in improving executive functions”
- HSA — Guidelines on prohibited and restricted ingredients in HS and TM (Oct 2025), Annex A · read 2026-08-27
what it says
“Annex A: List of substances which are prohibited or restricted for use with … [neither DMAE, deanol nor dimethylaminoethanol appears in Annex A or Annex B]”
- HSA — Health Supplements Guidelines (Jan 2026), Tables 4–5 vitamin and mineral limits · read 2026-08-27
what it says
“Table 4: Vitamins Limits … Table 5: Minerals Limits [neither table names DMAE or deanol]”
- iHerb Singapore — dmae category page (default best-selling order) · read 2026-08-27
what it says
“NOW Foods · Source Naturals · Force Factor · Vitacost · Life Extension [first distinct brands, default order]”
Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.