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Dimenhydrinate

Medication antihistamine antiemetic digestive
Aka: Dramamine, Gravol, dimenhydrinate BP
Brands seen in Singapore: Novomin, Apo-Dimenhydrinate, SW Dimenhydrinate, Dimenhydrinate Tablets, Votmine
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Nausea, vomiting, vertigo and motion sickness (HealthHub)
When to take
First dose 30 minutes before a journey, then every 8 hours
Take with
With or without food · alcohol adds to the drowsiness
Pros & cons
Pros
  • Cochrane: probably cuts the risk of motion sickness
  • HealthHub: with or without food; tablet, syrup or shot
  • 5 of 6 SG registrations are pharmacy only
Cons
  • Cochrane: untested for motion sickness already present
  • Cochrane: more likely to cause sedation than placebo
  • Dramamine label: under 2 — not unless a doctor directs
Sources
  1. HealthHub (MOH Singapore) — Dimenhydrinate, uses / administration / precautions (article last reviewed 26 Feb 2026) · read 2026-08-27
    what it says
    “Dimenhydrinate is used to prevent nausea and vomiting, vertigo {dizzy spells} or motion sickness … the first dose should be taken 30 minutes before the start of the journey and every 8 hours if needed for a longer journey”
  2. MOH National Drug Formulary — APO-DIMENHYDRINATE TABLET 50 MG [SIN02519P], product information (no dosing section published) · read 2026-08-27
    what it says
    “APO-DIMENHYDRINATE TABLET 50 MG [SIN02519P] … DIMENHYDRINATE BP - 50 MG … Licence Holder PHARMAFORTE SINGAPORE PTE LTD … Forensic Classification PHARMACY ONLY MEDICINES … ATC code A04AD”
  3. HSA register of therapeutic products (data.gov.sg d_767279312753558cbf19d48344577084) — 6 dimenhydrinate rows, filtered locally 27 Aug 26 · read 2026-08-27
    what it says
    “APO-DIMENHYDRINATE TABLET 50 mg … Pharmacy Only … NOVOMIN TABLET 50 mg … NOVOMIN SYRUP 15 mg/5 ml … SW DIMENHYDRINATE SYRUP … DIMENHYDRINATE TABLETS 50 mg … VOTMINE INJECTION 10 ML VIAL … Prescription Only”
  4. DailyMed / FDA OTC label — DRAMAMINE ORIGINAL FORMULA (dimenhydrinate 50 mg tablet), Medtech Products Inc., Directions (updated 23 Oct 2025) · read 2026-08-27
    what it says
    “Adults and children 12 years and over take 1 to 2 tables every 4-6 hours do not take more than 8 tablets in 24 hours, or as directed by a doctor”
  5. DailyMed / FDA OTC label — DRAMAMINE ORIGINAL FORMULA, Warnings · read 2026-08-27
    what it says
    “Do not give to children under 2 years of age unless directed by a doctor … Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers … alcohol, sedatives, and tranquilizers may increase dizziness”
  6. Cochrane Database of Systematic Reviews — Antihistamines for motion sickness (Karrim, Byrne, Magula, Saman 2022; PMC9575651), authors' conclusions · read 2026-08-27
    what it says
    “There is probably a reduction in the risk of developing motion sickness symptoms under naturally occurring conditions of motion when using first-generation antihistamines … No studies evaluated the treatment of existing motion sickness”
  7. Cochrane Database of Systematic Reviews — Antihistamines for motion sickness (Karrim et al. 2022), adverse effects and evidence gaps · read 2026-08-27
    what it says
    “Antihistamines may be more likely to cause sedation when compared to placebo … there are few data on the effect of antihistamines in children”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.