{"ok":true,"entry":{"slug":"dimenhydrinate","kind":"medication","name":"dimenhydrinate","aliases":["Dramamine","Gravol","dimenhydrinate BP"],"brands_sg":["Novomin","Apo-Dimenhydrinate","SW Dimenhydrinate","Dimenhydrinate Tablets","Votmine"],"class":"antihistamine antiemetic","tags":["digestive"],"use_for":"nausea, vomiting, vertigo and motion sickness (healthhub)","use_after":"first dose 30 minutes before a journey, then every 8 hours","use_duration":null,"take_with":"with or without food · alcohol adds to the drowsiness","pros":["cochrane: probably cuts the risk of motion sickness","healthhub: with or without food; tablet, syrup or shot","5 of 6 sg registrations are pharmacy only"],"cons":["cochrane: untested for motion sickness already present","cochrane: more likely to cause sedation than placebo","dramamine label: under 2 — not unless a doctor directs"],"dose_note":"no singapore label with a dose table could be found for the sg dimenhydrinate products — ndf publishes product details but no dosing section for APO-DIMENHYDRINATE TABLET 50 mg [SIN02519P], NOVOMIN TABLET 50 mg [SIN03403P], DIMENHYDRINATE TABLETS 50 mg [SIN02765P] or the 15 mg/5 ml syrups; the closest label with a stated ceiling is the us dramamine original formula 50 mg drug facts, which read 'Adults and children 12 years and over take 1 to 2 tables every 4-6 hours, do not take more than 8 tablets in 24 hours, or as directed by a doctor' (the word 'tables' is the label's own typo) — 8 × 50 mg is 400 mg a day at that strength — with 'do not give to children under 2 years of age unless directed by a doctor'; healthhub adds that for motion sickness the first dose is taken 30 minutes before the journey and every 8 hours if needed for a longer one; as directed on the label or by your doctor or pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["heart or liver disease, thyroid or lung conditions — healthhub says say so first","stomach obstruction, enlarged prostate, urinary obstruction or glaucoma — healthhub says say so first","epilepsy or seizures — healthhub says say so first","pregnant, planning to be, or breastfeeding — healthhub and the dramamine label both say ask first"],"clashes":[{"src":["healthhub_dimen"],"food":true,"note":"healthhub: avoid drinking alcohol while taking this medication as it can increase the drowsiness side effect","with":"alcohol"},{"src":["dailymed_dramamine_warn"],"note":"dramamine label: ask a doctor or pharmacist before use; alcohol, sedatives and tranquilizers may increase dizziness","with":"sedatives or tranquilizers"},{"src":["healthhub_dimen"],"note":"healthhub asks that you tell your healthcare professional what else you are taking; no specific interaction is named","with":"other medicines, supplements, traditional or herbal remedies"}],"sources":[{"id":"healthhub_dimen","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dimenhydrinate","label":"HealthHub (MOH Singapore) — Dimenhydrinate, uses / administration / precautions (article last reviewed 26 Feb 2026)","quote":"Dimenhydrinate is used to prevent nausea and vomiting, vertigo {dizzy spells} or motion sickness … the first dose should be taken 30 minutes before the start of the journey and every 8 hours if needed for a longer journey","accessed":"2026-08-27"},{"id":"ndf_apo_dimen","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02519p/","label":"MOH National Drug Formulary — APO-DIMENHYDRINATE TABLET 50 MG [SIN02519P], product information (no dosing section published)","quote":"APO-DIMENHYDRINATE TABLET 50 MG [SIN02519P] … DIMENHYDRINATE BP - 50 MG … Licence Holder PHARMAFORTE SINGAPORE PTE LTD … Forensic Classification PHARMACY ONLY MEDICINES … ATC code A04AD","accessed":"2026-08-27"},{"id":"hsa_register_dimen","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA register of therapeutic products (data.gov.sg d_767279312753558cbf19d48344577084) — 6 dimenhydrinate rows, filtered locally 27 Aug 26","quote":"APO-DIMENHYDRINATE TABLET 50 mg … Pharmacy Only … NOVOMIN TABLET 50 mg … NOVOMIN SYRUP 15 mg/5 ml … SW DIMENHYDRINATE SYRUP … DIMENHYDRINATE TABLETS 50 mg … VOTMINE INJECTION 10 ML VIAL … Prescription Only","accessed":"2026-08-27"},{"id":"dailymed_dramamine","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f9302a5a-295a-4501-9332-e3f5eb387362","label":"DailyMed / FDA OTC label — DRAMAMINE ORIGINAL FORMULA (dimenhydrinate 50 mg tablet), Medtech Products Inc., Directions (updated 23 Oct 2025)","quote":"Adults and children 12 years and over take 1 to 2 tables every 4-6 hours do not take more than 8 tablets in 24 hours, or as directed by a doctor","accessed":"2026-08-27"},{"id":"dailymed_dramamine_warn","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f9302a5a-295a-4501-9332-e3f5eb387362","label":"DailyMed / FDA OTC label — DRAMAMINE ORIGINAL FORMULA, Warnings","quote":"Do not give to children under 2 years of age unless directed by a doctor … Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers … alcohol, sedatives, and tranquilizers may increase dizziness","accessed":"2026-08-27"},{"id":"cochrane_motion2022","url":"https://europepmc.org/article/PMC/PMC9575651","label":"Cochrane Database of Systematic Reviews — Antihistamines for motion sickness (Karrim, Byrne, Magula, Saman 2022; PMC9575651), authors' conclusions","quote":"There is probably a reduction in the risk of developing motion sickness symptoms under naturally occurring conditions of motion when using first-generation antihistamines … No studies evaluated the treatment of existing motion sickness","accessed":"2026-08-27"},{"id":"cochrane_motion2022_ae","url":"https://europepmc.org/article/PMC/PMC9575651","label":"Cochrane Database of Systematic Reviews — Antihistamines for motion sickness (Karrim et al. 2022), adverse effects and evidence gaps","quote":"Antihistamines may be more likely to cause sedation when compared to placebo … there are few data on the effect of antihistamines in children","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:18.585742+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}