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Clopidogrel

Medication P2Y12 antiplatelet heart & blood pressure
Aka: Plavix, Iscover
Brands seen in Singapore: Plavix, Apo-Clopidogrel, Ceruvin, Deplatt, Placta
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Clot prevention after a heart attack, stroke or stent
When to take
SG label: a single daily dose of 75 mg
Take with
HealthHub: with or after food · SG label: with or without
Pros & cons
Pros
  • One 75 mg tablet a day
  • Sixteen 75 mg brands registered in SG
  • NHS: prescribed with, or instead of, low-dose aspirin
Cons
  • Bleeding more easily is the main side effect (NHS)
  • Omeprazole may make it work less well (NHS)
  • SG label: contraindicated with active bleeding
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows pulled once via the datastore_search API and filtered locally, 27 Aug 2026 · read 2026-08-27
    what it says
    “PLAVIX TABLET 75 mg SIN09828P | Prescription Only; Apo-Clopidogrel 75mg SIN13571P; CERUVIN 75MG SIN14037P; DEPLATT 75MG SIN13820P; PLACTA 75 mg SIN13844P — all 17 clopidogrel rows 'Prescription Only'; no ISCOVER row.”
  2. MOH National Drug Formulary (Singapore) — PLAVIX TABLET 75 MG [SIN09828P], clopidogrel, sanofi-aventis Singapore — product info and forensic classification · read 2026-08-27
    what it says
    “CLOPIDOGREL HYDROGEN SULPHATE EQV CLOPIDOGREL - 75 MG … TABLET, FILM COATED … Forensic Classification: PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code B01AC04 … Prescription-only Medicines with Exemptions for Supply without Prescription: NA”
  3. MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.1 therapeutic indications · read 2026-08-27
    what it says
    “Secondary prevention of atherothrombotic events. Clopidogrel is indicated in: Adult patients suffering from myocardial infarction (from a few days until less than 35 days), ischemic stroke (from 7 days until less than 6 months) or established peripheral arterial disease.”
  4. MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.2 posology and method of administration · read 2026-08-27
    what it says
    “Clopidogrel should be given as a single daily dose of 75 mg … initiated with a single 300 mg or 600 mg loading dose … it is recommended that the dose of ASA should not be higher than 100 mg”
  5. MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.3 contraindications and paediatric use · read 2026-08-27
    what it says
    “Hypersensitivity to the active substance or to any of the excipients. Severe liver impairment. Active pathological bleeding such as peptic ulcer or intracranial hemorrhage … Clopidogrel should not be used in children because of efficacy concerns”
  6. HealthHub (MOH Singapore) — Clopidogrel, Medication Information Leaflet, last reviewed 21 May 2026 · read 2026-08-27
    what it says
    “Clopidogrel belongs to the class of medications called antiplatelets … used to prevent blood clots from forming by making the blood less “sticky” … This medicine should be taken with or after food … You have kidney or liver problems”
  7. HealthHub (MOH Singapore) — Clopidogrel, food and medication to avoid · read 2026-08-27
    what it says
    “Avoid taking large amount of grapefruit or its juice when you are taking this medication as it may interact with your medication and reduce its effectiveness.”
  8. NHS medicines A–Z — About clopidogrel, brand names Grepid, Plavix (page last reviewed 12 March 2025) · read 2026-08-27
    what it says
    “Clopidogrel is an antiplatelet medicine … You'll usually take clopidogrel once a day. Your doctor may prescribe clopidogrel with or instead of low-dose aspirin. The main side effect of clopidogrel is bleeding more easily than normal.”
  9. NHS medicines A–Z — Taking clopidogrel with other medicines and herbal supplements · read 2026-08-27
    what it says
    “The indigestion medicines omeprazole and esomeprazole may affect how well clopidogrel works … Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you're taking clopidogrel … You can take paracetamol together with clopidogrel.”
  10. MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.2 method of administration · read 2026-08-27
    what it says
    “Method of administration: For oral use. It may be given with or without food.”
  11. NHS medicines A–Z — Clopidogrel, cautions with other medicines (list) · read 2026-08-27
    what it says
    “other medicines to prevent blood clots, such as low-dose aspirin, warfarin, rivaroxaban, apixaban, edoxaban, dabigatran, dipyridamole, ticagrelor or prasugrel … antidepressants called selective serotonin reuptake inhibitors (SSRIs), such as citalopram”
  12. NHS medicines A–Z — Clopidogrel, mixing it with herbal remedies and supplements · read 2026-08-27
    what it says
    “St John's wort (used for depression) can increase the levels of clopidogrel in your blood. This can increase your risk of bleeding … especially ones that can affect your blood (for example, ginkgo)”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.