{"ok":true,"entry":{"slug":"clopidogrel","kind":"medication","name":"clopidogrel","aliases":["Plavix","Iscover"],"brands_sg":["Plavix","Apo-Clopidogrel","Ceruvin","Deplatt","Placta"],"class":"P2Y12 antiplatelet","tags":["heart-bp"],"use_for":"clot prevention after a heart attack, stroke or stent","use_after":"sg label: a single daily dose of 75 mg","use_duration":null,"take_with":"healthhub: with or after food · sg label: with or without","pros":["one 75 mg tablet a day","sixteen 75 mg brands registered in sg","nhs: prescribed with, or instead of, low-dose aspirin"],"cons":["bleeding more easily is the main side effect (nhs)","omeprazole may make it work less well (nhs)","sg label: contraindicated with active bleeding"],"dose_note":"sg plavix label (sin09828p): 'Clopidogrel should be given as a single daily dose of 75 mg' — that is the maintenance ceiling; in acute coronary syndrome the label describes 'a single 300 mg or 600 mg loading dose' first, then treatment 'continued at 75 mg once a day', and where aspirin is combined 'it is recommended that the dose of ASA should not be higher than 100 mg'; 'Clopidogrel should not be used in children because of efficacy concerns' — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["surgery, or dental or medical procedures coming up — healthhub: these medications may need to be stopped temporarily beforehand; nhs: check with the doctor or dentist first","a history of stomach or intestinal ulcers or bleeds, or bleeding in the brain — healthhub lists these; active pathological bleeding is an sg label contraindication","liver or kidney problems — healthhub lists both; severe liver impairment is an sg label contraindication","children — sg label: not used because of efficacy concerns"],"clashes":[{"src":["nhs_clopidogrel_med"],"note":"nhs: these indigestion medicines may affect how well clopidogrel works; a doctor can prescribe another, such as lansoprazole","with":"omeprazole or esomeprazole"},{"src":["nhs_clopidogrel_list","nhs_clopidogrel_about"],"note":"nhs lists other antithrombotics among medicines to tell a doctor about; low-dose aspirin is sometimes prescribed alongside on purpose","with":"other blood thinners (warfarin, rivaroxaban, ticagrelor, low-dose aspirin)"},{"src":["nhs_clopidogrel_med"],"note":"nhs: not to be taken while on clopidogrel unless a doctor has said it is ok, as they increase the chance of bleeding; paracetamol is fine","with":"nsaids — ibuprofen, or 300 mg aspirin for pain"},{"src":["nhs_clopidogrel_list"],"note":"nhs lists ssris among medicines that affect the way clopidogrel works","with":"ssri antidepressants such as citalopram"},{"src":["healthhub_clopidogrel_food","nhs_clopidogrel_herbs"],"food":true,"note":"healthhub: large amounts of grapefruit may reduce its effectiveness; nhs: st john's wort raises clopidogrel levels and herbs affecting the blood, such as ginkgo, may be a problem","with":"grapefruit, st john's wort and ginkgo"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows pulled once via the datastore_search API and filtered locally, 27 Aug 2026","quote":"PLAVIX TABLET 75 mg SIN09828P | Prescription Only; Apo-Clopidogrel 75mg SIN13571P; CERUVIN 75MG SIN14037P; DEPLATT 75MG SIN13820P; PLACTA 75 mg SIN13844P — all 17 clopidogrel rows 'Prescription Only'; no ISCOVER row.","accessed":"2026-08-27"},{"id":"ndf_plavix","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09828p/","label":"MOH National Drug Formulary (Singapore) — PLAVIX TABLET 75 MG [SIN09828P], clopidogrel, sanofi-aventis Singapore — product info and forensic classification","quote":"CLOPIDOGREL HYDROGEN SULPHATE EQV CLOPIDOGREL - 75 MG … TABLET, FILM COATED … Forensic Classification: PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code B01AC04 … Prescription-only Medicines with Exemptions for Supply without Prescription: NA","accessed":"2026-08-27"},{"id":"ndf_plavix_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09828p/","label":"MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.1 therapeutic indications","quote":"Secondary prevention of atherothrombotic events. Clopidogrel is indicated in: Adult patients suffering from myocardial infarction (from a few days until less than 35 days), ischemic stroke (from 7 days until less than 6 months) or established peripheral arterial disease.","accessed":"2026-08-27"},{"id":"ndf_plavix_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09828p/","label":"MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.2 posology and method of administration","quote":"Clopidogrel should be given as a single daily dose of 75 mg … initiated with a single 300 mg or 600 mg loading dose … it is recommended that the dose of ASA should not be higher than 100 mg","accessed":"2026-08-27"},{"id":"ndf_plavix_ci","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09828p/","label":"MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.3 contraindications and paediatric use","quote":"Hypersensitivity to the active substance or to any of the excipients. Severe liver impairment. Active pathological bleeding such as peptic ulcer or intracranial hemorrhage … Clopidogrel should not be used in children because of efficacy concerns","accessed":"2026-08-27"},{"id":"healthhub_clopidogrel","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clopidogrel","label":"HealthHub (MOH Singapore) — Clopidogrel, Medication Information Leaflet, last reviewed 21 May 2026","quote":"Clopidogrel belongs to the class of medications called antiplatelets … used to prevent blood clots from forming by making the blood less “sticky” … This medicine should be taken with or after food … You have kidney or liver problems","accessed":"2026-08-27"},{"id":"healthhub_clopidogrel_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clopidogrel","label":"HealthHub (MOH Singapore) — Clopidogrel, food and medication to avoid","quote":"Avoid taking large amount of grapefruit or its juice when you are taking this medication as it may interact with your medication and reduce its effectiveness.","accessed":"2026-08-27"},{"id":"nhs_clopidogrel_about","url":"https://www.nhs.uk/medicines/clopidogrel/about-clopidogrel/","label":"NHS medicines A–Z — About clopidogrel, brand names Grepid, Plavix (page last reviewed 12 March 2025)","quote":"Clopidogrel is an antiplatelet medicine … You'll usually take clopidogrel once a day. Your doctor may prescribe clopidogrel with or instead of low-dose aspirin. The main side effect of clopidogrel is bleeding more easily than normal.","accessed":"2026-08-27"},{"id":"nhs_clopidogrel_med","url":"https://www.nhs.uk/medicines/clopidogrel/taking-clopidogrel-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Taking clopidogrel with other medicines and herbal supplements","quote":"The indigestion medicines omeprazole and esomeprazole may affect how well clopidogrel works … Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you're taking clopidogrel … You can take paracetamol together with clopidogrel.","accessed":"2026-08-27"},{"id":"ndf_plavix_admin","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09828p/","label":"MOH National Drug Formulary (Singapore) — PLAVIX [SIN09828P], 4.2 method of administration","quote":"Method of administration: For oral use. It may be given with or without food.","accessed":"2026-08-27"},{"id":"nhs_clopidogrel_list","url":"https://www.nhs.uk/medicines/clopidogrel/taking-clopidogrel-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Clopidogrel, cautions with other medicines (list)","quote":"other medicines to prevent blood clots, such as low-dose aspirin, warfarin, rivaroxaban, apixaban, edoxaban, dabigatran, dipyridamole, ticagrelor or prasugrel … antidepressants called selective serotonin reuptake inhibitors (SSRIs), such as citalopram","accessed":"2026-08-27"},{"id":"nhs_clopidogrel_herbs","url":"https://www.nhs.uk/medicines/clopidogrel/taking-clopidogrel-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Clopidogrel, mixing it with herbal remedies and supplements","quote":"St John's wort (used for depression) can increase the levels of clopidogrel in your blood. This can increase your risk of bleeding … especially ones that can affect your blood (for example, ginkgo)","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:16.693643+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}