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Clobetasol

Medication very potent topical corticosteroid skin
Aka: Dermovate
Brands seen in Singapore: Dermovate, Medodermone, Univate, Lobesol, Tempovate
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
NHS: eczema, psoriasis, lichen planus and discoid lupus
When to take
SG label: sparingly to the area, once or twice daily
Take with
Topical only · NHS: 30 minutes apart from other creams
Pros & cons
Pros
  • NHS: much stronger than other steroid treatments
  • SG label: psoriasis, recalcitrant eczema, lichen planus
  • SG label: short repeat courses can control flare-ups
Cons
  • NHS: can thin the skin; on the face only 5 days
  • US label: over 50 g a week is not to be used
  • NHS: stopping suddenly can trigger a withdrawal flare
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 16 registered clobetasol propionate products read 'Prescription Only' — DERMOVATE cream, ointment and scalp application · MEDODERMONE · UNIVATE · LOBESOL · TEMPOVATE · CLODERM · STERIDERM-S · DERMOSOL · CLONOVATE · CLOBEX shampoo”
  2. National Drug Formulary (SG, MOH) — DERMOVATE CREAM 0.05% W/W [SIN04934P], approved indications and dosing · read 2026-08-27
    what it says
    “Apply sparingly to the affected area once or twice daily … Treatment should not be continued for more than four weeks without the patient's condition being reviewed. Repeated short courses of DERMOVATE may be used to control exacerbations.”
  3. NHS — Clobetasol (Dermovate): steroid for skin conditions · read 2026-08-27
    what it says
    “Clobetasol is much stronger than other steroid treatments … used to treat skin conditions such as: eczema psoriasis lichen planus discoid lupus erythematosus … should only be used on your face for 5 days”
  4. US FDA label — clobetasol propionate ointment USP 0.05%, DOSAGE AND ADMINISTRATION, via openFDA · read 2026-08-27
    what it says
    “treatment should be limited to 2 consecutive weeks, and amounts greater than 50 g per week should not be used … should not be used with occlusive dressings”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.