{"ok":true,"entry":{"slug":"clobetasol","kind":"medication","name":"clobetasol","aliases":["Dermovate"],"brands_sg":["Dermovate","Medodermone","Univate","Lobesol","Tempovate"],"class":"very potent topical corticosteroid","tags":["skin"],"use_for":"nhs: eczema, psoriasis, lichen planus and discoid lupus","use_after":"sg label: sparingly to the area, once or twice daily","use_duration":null,"take_with":"topical only · nhs: 30 minutes apart from other creams","pros":["nhs: much stronger than other steroid treatments","sg label: psoriasis, recalcitrant eczema, lichen planus","sg label: short repeat courses can control flare-ups"],"cons":["nhs: can thin the skin; on the face only 5 days","us label: over 50 g a week is not to be used","nhs: stopping suddenly can trigger a withdrawal flare"],"dose_note":"the singapore dermovate label caps duration rather than amount: it is applied 'sparingly to the affected area once or twice daily' and 'treatment should not be continued for more than four weeks without the patient's condition being reviewed'. the us clobetasol propionate 0.05% label is stricter on both counts — 'treatment should be limited to 2 consecutive weeks, and amounts greater than 50 g per week should not be used' — and adds that it 'should not be used with occlusive dressings'. nhs says it 'should only be used on your face for 5 days'. every one of the 16 sg-registered clobetasol products is 0.05%.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["skin infection, acne or rosacea — nhs: may not be suitable","under 1 year — sg label: contraindicated in that age group","long courses or large areas — nhs: adrenal and cushing's risk","pregnancy or breastfeeding — nhs: check with a doctor first"],"clashes":[{"src":["nhs_clobetasol"],"note":"nhs: at least 30 minutes between clobetasol and another product","with":"moisturisers and other creams"},{"src":["fda_clobetasol_dose","nhs_clobetasol"],"note":"us label: not to be used with occlusive dressings","with":"occlusive dressings or plasters"},{"src":["nhs_clobetasol"],"note":"nhs: clothing and bedding in contact with it burn more easily","with":"naked flames and smoking"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 16 registered clobetasol propionate products read 'Prescription Only' — DERMOVATE cream, ointment and scalp application · MEDODERMONE · UNIVATE · LOBESOL · TEMPOVATE · CLODERM · STERIDERM-S · DERMOSOL · CLONOVATE · CLOBEX shampoo","accessed":"2026-08-27"},{"id":"ndf_dermovate","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN04934P","label":"National Drug Formulary (SG, MOH) — DERMOVATE CREAM 0.05% W/W [SIN04934P], approved indications and dosing","quote":"Apply sparingly to the affected area once or twice daily … Treatment should not be continued for more than four weeks without the patient's condition being reviewed. Repeated short courses of DERMOVATE may be used to control exacerbations.","accessed":"2026-08-27"},{"id":"nhs_clobetasol","url":"https://www.nhs.uk/medicines/clobetasol/","label":"NHS — Clobetasol (Dermovate): steroid for skin conditions","quote":"Clobetasol is much stronger than other steroid treatments … used to treat skin conditions such as: eczema psoriasis lichen planus discoid lupus erythematosus … should only be used on your face for 5 days","accessed":"2026-08-27"},{"id":"fda_clobetasol_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22CLOBETASOL%20PROPIONATE%22&limit=1","label":"US FDA label — clobetasol propionate ointment USP 0.05%, DOSAGE AND ADMINISTRATION, via openFDA","quote":"treatment should be limited to 2 consecutive weeks, and amounts greater than 50 g per week should not be used … should not be used with occlusive dressings","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:16.693643+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}