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Citrus bergamot

Supplement botanical heart & metabolic
Aka: Citrus bergamia, bergamot polyphenols
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Lipid and waistline markers in trials of ≤600 mg/day
Studied for
Trials run 4–12 weeks; longer use is untested
Pros & cons
Pros
  • 11-RCT meta-analysis: lower weight, BMI and waist
  • Lipid effects have several clinical studies behind them
Cons
  • Pooled results very heterogeneous (I² = 90%)
  • Vascular and anti-inflammatory data are preclinical
  • SG bars 'reduces cholesterol' claims on supplements
Sources
  1. Effect of Citrus bergamia Supplementation on Body Composition in Humans: systematic review and meta-analysis of RCTs (Obesity Reviews 2026) · read 2026-08-27
    what it says
    “C. bergamia supplementation significantly decreased body weight (SMD: -0.64; 95% CI: -1.15, -0.13; p = 0.01; I2 = 90%) … significantly changed anthropometric parameters for periods of ≤ 12 weeks, at dosages of ≤ 600 mg/day”
  2. Unveiling the Power of Bergamot: Beyond Lipid-Lowering Effects (Nutrients 2025) · read 2026-08-27
    what it says
    “While lipid effects are supported by several clinical studies, evidence for vascular and inflammatory pathways is based mainly on preclinical studies … a promising adjunctive or alternative therapeutic option in specific clinical contexts”
  3. HSA — Health Supplements Guidelines (Jan 2026), Tables 4 & 5 vitamin/mineral limits · read 2026-08-27
    what it says
    “HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
  4. HSA — Health Supplements Guidelines (Jan 2026), Table 6 prohibited claims · read 2026-08-27
    what it says
    “HS must not be labelled, advertised or promoted for any specific medicinal purpose … Blood and circulatory system: Hypertension, stroke, cholesterol disorders, reduces cholesterol, regulates platelet aggregation”
  5. HSA — Guidelines on prohibited and restricted ingredients in HS and TM (Oct 2025), Annex A/B · read 2026-08-27
    what it says
    “A list of specific prohibited and restricted ingredients is provided in Annex A … This list is not exhaustive. Dealers should continue to: Conduct thorough safety assessments of their products”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.