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Ciclosporin

Medication calcineurin-inhibitor immunosuppressant other
Aka: cyclosporine, Neoral, Sandimmun
Brands seen in Singapore: Sandimmun Neoral, Sandimmun, Deximune, Strineora, Ikervis
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
HealthHub: psoriasis, eczema, lupus, transplant rejection
When to take
HealthHub: usually twice daily, kept steady with meals
Take with
HealthHub: capsules swallowed whole with a glass of water
Pros & cons
Pros
  • HealthHub: tunes down an over-aggressive immune attack
  • SG label: also covers uveitis, ra, psoriasis, eczema
  • Register: capsules, oral solution and eye drops in SG
Cons
  • HealthHub: raises kidney markers and blood pressure
  • HealthHub: gum overgrowth, tremor, extra body hair
  • HealthHub: infection risk rises while taking it
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084); all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 12 ciclosporin/cyclosporine rows · read 2026-08-27
    what it says
    “SANDIMMUN NEORAL CAPSULE 100 mg SIN08177P · SANDIMMUN CONCENTRATE FOR INFUSION SIN00520P · DEXIMUNE CAPSULES 25MG SIN14047P · STRINEORA 100 SIN17521P · IKERVIS EYE DROPS SIN15216P — all 12 rows read Forensicclassification “Prescription Only” (ATC L04AD01, S01XA18)”
  2. HealthHub (Pharmaceutical Society of Singapore / MOH) — Ciclosporin: what is this medication for · read 2026-08-27
    what it says
    “Ciclosporin is used in conditions such as Systemic Lupus Erythematosus, psoriasis and eczema and to prevent rejection of transplanted organs. It “tames” your immune system and in turn, tunes down the aggressiveness of its attack”
  3. HealthHub — Ciclosporin: how should I take or use this medication · read 2026-08-27
    what it says
    “It is given orally, consistent with relation to time of day and meals. Ciclosporin is usually given twice daily … Swallow your capsules with a glass of water. Do not break or crush them”
  4. HealthHub — Ciclosporin: what precautions should I take · read 2026-08-27
    what it says
    “If you have cancer, kidney problems, or high blood pressure … Seek prompt advice from your doctor when you develop any symptoms of infection e.g. fever, sore throat, yellow/green phlegm, urinary tract infection”
  5. HealthHub — Ciclosporin: common side effects · read 2026-08-27
    what it says
    “More than 10% of people will experience: Increase in kidney marker; High blood pressure; Headache including migraine; Tremor … Inflammation/overgrowth of gums … Hair overgrowth in male-like pattern”
  6. HealthHub — Ciclosporin: what food or medication should I avoid · read 2026-08-27
    what it says
    “Avoid taking grapefruits, pomelo, pineapple, or starfruit during treatment with Ciclosporin. You should avoid live vaccines such as live polio, yellow fever, rubella (German measles), MMR … Flu and pneumococcal vaccines are safe”
  7. Singapore National Drug Formulary — SANDIMMUN NEORAL CAPSULE 100 mg [SIN08177P], Dosage and Administration · read 2026-08-27
    what it says
    “Except in patients with refractory cases of sight-threatening endogenous uveitis and in children with nephrotic syndrome, the total daily dose must never exceed 5 mg/kg.”
  8. Singapore National Drug Formulary — SANDIMMUN NEORAL [SIN08177P], Indications and psoriasis dosing · read 2026-08-27
    what it says
    “the recommended initial dose is 2.5 mg/kg per day orally given in 2 divided doses. If there is no improvement after 1 month, the daily dose may be gradually increased, but should not exceed 5 mg/kg”
  9. Singapore National Drug Formulary — SANDIMMUN NEORAL [SIN08177P], Contraindications (non-transplant indications) · read 2026-08-27
    what it says
    “Uncontrolled hypertension; Uncontrolled infection; History of known or diagnosed malignancy of any kind except premalignant or malignant skin changes.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.