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Chamomile

Supplement botanical sleep
Aka: Matricaria chamomilla, German chamomile
Brands seen in Singapore: Nature's Answer, Swanson Vitamins, Nature's Way, Nutricost, Solaray
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Sold for sleep and anxiety · reliable evidence is thin
Take with
Commonly consumed as a tea
Pros & cons
Pros
  • A 2024 meta-analysis found lower psqi sleep scores
  • Ten trials, 772 people, pooled for that review
  • Likely safe in the amounts commonly found in teas
Cons
  • NCCIH: not enough reliable evidence to rate usefulness
  • A 2019 review found one insomnia study, no benefit
  • Ragweed or daisy allergy? anaphylaxis is reported
Sources
  1. NIH NCCIH — Chamomile (German chamomile), uses and evidence · read 2026-08-27
    what it says
    “Studies of the effectiveness of chamomile for a variety of specific conditions have not produced sufficient reliable evidence to rate clinical usefulness … likely safe when used orally in amounts commonly found in teas”
  2. NIH NCCIH — Chamomile, insomnia section · read 2026-08-27
    what it says
    “There's very little information on chamomile's effect on insomnia. A 2019 review of chamomile use found one study on insomnia, which found no benefit from its use for this sleep disorder.”
  3. NIH NCCIH — Chamomile, side effects and pregnancy · read 2026-08-27
    what it says
    “nausea, dizziness, and allergic reactions, including severe hypersensitivity reactions and anaphylaxis, in some people … Little is known about whether it's safe to use chamomile during pregnancy or while breastfeeding.”
  4. NIH NCCIH — Chamomile, cross-allergy to the daisy family · read 2026-08-27
    what it says
    “People are more likely to experience allergic reactions to chamomile if they're allergic to related plants such as ragweed, chrysanthemums, marigolds, or daisies.”
  5. NIH NCCIH — Chamomile, drug interactions · read 2026-08-27
    what it says
    “Interactions between chamomile and some drugs metabolized by the liver and warfarin (a blood thinner) have been reported … there are theoretical reasons to suspect that chamomile might interact with other drugs as well, such as sedatives”
  6. Effects of chamomile (Matricaria chamomilla L.) on sleep: a systematic review and meta-analysis of clinical trials (Kazemi et al., Complement Ther Med 2024;85:103071) · read 2026-08-27
    what it says
    “The systematic review included ten studies (772 participants) … A significant reduction in PSQI score (WMD: -1.88, 95 %CI: -3.46, -0.31, I2: 88.4 %, n = 5) was found … Sleep efficiency did not change in two studies and deteriorated in one.”
  7. The Effect of Oral Chamomile on Anxiety: A Systematic Review of Clinical Trials (Saadatmand et al., Clin Nutr Res 2024;13:139) · read 2026-08-27
    what it says
    “Out of the 10 articles selected, 9 studies have concluded that chamomile is effective in reducing anxiety … its active compounds, including apigenin, may modulate the function of the hypothalamic-pituitary-adrenocortical axis by affecting neurotransmitter pathways.”
  8. HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 (Oct 2025), Annex A/B — searched, no row for this ingredient · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  9. HSA Singapore — Health Supplements Guidelines (January 2026), clause 4.8 and Tables 4–5 (vitamins and minerals only) · read 2026-08-27
    what it says
    “HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.”
  10. iHerb Singapore — Supplements > Herbs > Chamomile Supplements category page, default order (1 - 10 of 10 results); first 5 distinct brands: Nature's Answer, Swanson Vitamins, Nature's Way, Nutricost, Solaray · read 2026-08-27
    what it says
    “Nature's Answer, Chamomile Extract, Alcohol Free, 1 fl oz (30 ml) … Swanson Vitamins, Chamomile, 350 mg, 120 Capsules … Nature's Way, Chamomile Flower, 700 mg … Nutricost, Chamomile, 240 Capsules … Solaray, True Herbs, Chamomile, 350 mg”

Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.