Chaga
Supplement
mushroom
immune
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Limited human evidence — mostly polysaccharide lab research
Pros & cons
Pros
- A 2026 review groups it with immune mushrooms
- Widely studied as a source of polysaccharides
- Named among the most studied medicinal mushrooms
Cons
- Case report: oxalate kidney injury at 10-15 g a day
- That case needed dialysis and high-dose steroids
- Human efficacy data is thin — reviews are lab-based
Sources
- Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report (Medicine 2022) — exposure · read 2026-08-27
what it says
“A 69-year-old man who ingested Chaga mushroom powder (10-15 g per day) and vitamin C (500 mg per day) for the past 3 months developed acute kidney injury (AKI)”
- Chaga oxalate nephropathy case report, Medicine 2022 — reported mechanism · read 2026-08-27
what it says
“recent studies have reported that excessive ingestion of Chaga mushrooms can cause acute oxalate nephropathy … the deposition of calcium oxalate crystals in the tubules”
- Chaga oxalate nephropathy case report, Medicine 2022 — treatment required · read 2026-08-27
what it says
“we recommended hemodialysis and the administration of a high dose of steroids (intravenous hydrocortisone 500 mg twice a day for 3 days and oral prednisolone at 1 mg/kg)”
- Inonotus obliquus Polysaccharides: Preparation, Structural Characteristics, Structure-Activity Relationships, Biological Activities and Applications (Nutrients 2026) · read 2026-08-27
what it says
“this review summarizes its isolation and purification methods, structural characteristics, structure-activity relationships, biological properties and mechanisms, as well as their potential applications”
- Medicinal Mushrooms and Their Bioactive Compounds: From Traditional Use to Therapeutic Potential (Molecules 2026) — species in scope · read 2026-08-27
what it says
“Among the most widely studied and utilized species are Ganoderma lucidum, Lentinula edodes, Grifola frondosa, Cordyceps militaris, Cordyceps sinensis, Trametes versicolor, and Inonotus obliquus.”
- Medicinal Mushrooms and Their Bioactive Compounds, Molecules 2026 — what the clinical literature shows · read 2026-08-27
what it says
“Experimental and clinical studies indicate that extracts derived from these species may support immune function, modulate inflammatory responses, and exhibit antioxidant, antimicrobial, and anticancer properties.”
- HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025), Annex A/B — searched, no row for this ingredient · read 2026-08-27
what it says
“The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
- iHerb Singapore — Chaga category (default order, 32 results); first 5 distinct brands: California Gold Nutrition, Swanson Vitamins, Nutricost, Real Mushrooms, Host Defense · read 2026-08-27
what it says
“California Gold Nutrition, Fungiology, MushRex Plus … Swanson Vitamins, Full Spectrum® Chaga Mushroom, 400 mg … Nutricost, Organic Chaga Mushroom … Real Mushrooms, Chaga, Mushroom Extract Powder … Host Defense, Mushrooms™, Chaga”
Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.