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Ceramides

Supplement lipid skin & hair
Aka: phytoceramides, rice ceramides, konjac ceramides
Brands seen in Singapore: Idealove, Dr. Althea, Vanicream, G9skin, Purito
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Skin barrier — lower water loss in one 12-week trial
When to take
Daily
Studied for
The water-loss effect showed only at 12 weeks
Pros & cons
Pros
  • One randomised placebo-controlled trial supports it
  • No supplement-related adverse events in that trial
Cons
  • Limited human evidence — one 30-person trial
  • Tested only in healthy Japanese adults
  • 12 weeks passed before water loss differed
Sources
  1. Efficacy and Safety of Oral Administration of Wine Lees Extract (WLE)-Derived Ceramides and Glucosylceramides in Enhancing Skin Barrier Function (Nutrients 2024) — randomised, double-blind, placebo-controlled trial · read 2026-08-27
    what it says
    “A randomized, double-blind, placebo-controlled study was conducted with 30 healthy Japanese subjects … after 12 weeks of administration, the test group had significantly lower TEWL than the placebo (p = 0.04) … No adverse events related to the supplements were reported”
  2. HSA — Guidelines on health supplements (Singapore), maximum daily limits Tables 4–5 · read 2026-08-27
    what it says
    “Table 4: Vitamins Limits … Nutrient Maximum Daily Limit … Table 5: Minerals Limits”
  3. HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  4. iHerb Singapore — Ceramides: Barrier Creams, Serums & Capsules category page (default best-selling order) · read 2026-08-27
    what it says
    “Ceramides: Barrier Creams, Serums & Capsules”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.