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Celery seed

Supplement botanical general nutrition
Aka: Apium graveolens
Brands seen in Singapore: Natural Factors, Swanson Vitamins, Solaray, Eclectic Herb, Vitacost
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Joint comfort — trialled with boswellia, not on its own
When to take
Daily use
Studied for
The metabolic-syndrome trial ran 12 weeks
Pros & cons
Pros
  • Meta-analysis of 10 RCTs, 511 participants
  • No adverse-event difference vs placebo in trials
  • One trial reported lower uric acid at 150 mg/day
Cons
  • The knee-OA trial paired celery seed with boswellia
  • Meta-analysis flags heterogeneity and small samples
  • Joint outcomes not tested for celery seed alone
Sources
  1. Effects of celery (Apium graveolens) on blood pressure, glycemic and lipid profile in adults: systematic review and meta-analysis of RCTs (Front Nutr, 2025) · read 2026-08-27
    what it says
    “Our meta-analysis included ten randomized controlled studies with a total of 511 participants … celery seeds or celery preparations exceeding 1,000 mg/day were more effective than other parts of celery … no significant difference in adverse events between celery and placebo.”
  2. Efficacy and safety of Boswellia serrata and Apium graveolens L. extract against knee osteoarthritis and cartilage degeneration: RCT (Pharm Res, 2025) · read 2026-08-27
    what it says
    “A randomized, placebo-controlled, double-blind clinical trial was conducted in 62 participants using a nutraceutical [standardized Boswellia serrata Roxb. gum resin (300 mg) and Apium graveolens L. seed extract (250 mg)]”
  3. Effect of celery seed (Apium graveolens L.) administration on the components of metabolic syndrome, insulin sensitivity, and insulin secretion: a clinical trial (Pharmaceuticals, 2026) · read 2026-08-27
    what it says
    “Fourteen patients randomly received celery seed (150 mg/day) for 12 weeks … Celery seed administration significantly reduced SBP, DBP, TG, VLDL, and uric acid.”
  4. HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  5. iHerb Singapore — Celery Seed Supplements category page (default best-selling order) · read 2026-08-27
    what it says
    “Celery Seed Supplements”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.