{"ok":true,"entry":{"slug":"celery-seed","kind":"supplement","name":"celery seed","aliases":["Apium graveolens"],"brands_sg":["Natural Factors","Swanson Vitamins","Solaray","Eclectic Herb","Vitacost"],"class":"botanical","tags":["general"],"use_for":"joint comfort — trialled with boswellia, not on its own","use_after":"daily use","use_duration":"the metabolic-syndrome trial ran 12 weeks","take_with":null,"pros":["meta-analysis of 10 RCTs, 511 participants","no adverse-event difference vs placebo in trials","one trial reported lower uric acid at 150 mg/day"],"cons":["the knee-OA trial paired celery seed with boswellia","meta-analysis flags heterogeneity and small samples","joint outcomes not tested for celery seed alone"],"dose_note":"the metabolic-syndrome trial used 150 mg/day for 12 weeks; the meta-analysis reports celery seeds or preparations exceeding 1,000 mg/day were more effective","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["on blood-pressure medicines — trials report lower readings","singapore: not listed in HSA annex A/B — that is not the same as cleared"],"clashes":[],"sources":[{"id":"epmc_celery_ma2025","url":"https://europepmc.org/article/PMC/PMC12321563","label":"Effects of celery (Apium graveolens) on blood pressure, glycemic and lipid profile in adults: systematic review and meta-analysis of RCTs (Front Nutr, 2025)","quote":"Our meta-analysis included ten randomized controlled studies with a total of 511 participants … celery seeds or celery preparations exceeding 1,000 mg/day were more effective than other parts of celery … no significant difference in adverse events between celery and placebo.","accessed":"2026-08-27"},{"id":"epmc_celery_oa2025","url":"https://europepmc.org/article/PMC/PMC11880083","label":"Efficacy and safety of Boswellia serrata and Apium graveolens L. extract against knee osteoarthritis and cartilage degeneration: RCT (Pharm Res, 2025)","quote":"A randomized, placebo-controlled, double-blind clinical trial was conducted in 62 participants using a nutraceutical [standardized Boswellia serrata Roxb. gum resin (300 mg) and Apium graveolens L. seed extract (250 mg)]","accessed":"2026-08-27"},{"id":"epmc_celery_mets2026","url":"https://europepmc.org/article/PMC/PMC12845499","label":"Effect of celery seed (Apium graveolens L.) administration on the components of metabolic syndrome, insulin sensitivity, and insulin secretion: a clinical trial (Pharmaceuticals, 2026)","quote":"Fourteen patients randomly received celery seed (150 mg/day) for 12 weeks … Celery seed administration significantly reduced SBP, DBP, TG, VLDL, and uric acid.","accessed":"2026-08-27"},{"id":"hsa_prohibited","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/celery-seed","label":"iHerb Singapore — Celery Seed Supplements category page (default best-selling order)","quote":"Celery Seed Supplements","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:14.713299+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}