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Celecoxib

Medication COX-2 selective NSAID pain & fever
Aka: Celebrex
Brands seen in Singapore: Celebrex, Celecoxib Sandoz, Hovid-Celecoxib, Estacoxib, Aclexa
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
HealthHub: pain and inflammation, e.g. in arthritis
When to take
HealthHub: with or without food, as prescribed
Take with
Water · HealthHub: not alongside other NSAIDs
Pros & cons
Pros
  • HealthHub: for osteoarthritis, ra and acute pain
  • HealthHub: may be taken with or without food
  • Hh: can be taken as needed for short-term use
Cons
  • Hh: higher blood pressure, swollen ankles, gut upset
  • Hh: prolonged unsupervised use raises heart/stroke risk
  • Hh: stomach or gut bleeding is a rare, serious risk
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 14 registered celecoxib products carry 'Prescription Only' — SIN11240P/SIN11241P/SIN13653P CELEBREX CAPSULES 100 mg, 200 mg, 400MG · Celecoxib Sandoz 200mg · HOVID-CELECOXIB 200MG · Estacoxib 200mg · ACLEXA 200MG”
  2. HealthHub (National Medication Information workgroup, SG) — Celecoxib: what is this medication for · read 2026-08-27
    what it says
    “Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and reduce inflammation (redness, swelling and soreness) … Osteoarthritis … Rheumatoid arthritis … Ankylosing spondylitis … Acute pain conditions”
  3. HealthHub — Celecoxib: how should I take this medication · read 2026-08-27
    what it says
    “You may take this medication with or without food. Follow the instructions on your medication label and take this medication as prescribed by your doctor.”
  4. HealthHub — Celecoxib: if you forget a dose · read 2026-08-27
    what it says
    “Celecoxib can be taken on as needed basis for short term use as prescribed by the doctor … Do not double your dose or use extra medication to make up for the missed dose.”
  5. HealthHub — Celecoxib: common side effects · read 2026-08-27
    what it says
    “Increase in blood pressure; Fluid build up with swollen ankles, legs and/or hands; Stomach discomfort/irritation e.g. stomach pain, diarrhoea”
  6. HealthHub — Celecoxib: precautions on dose and duration · read 2026-08-27
    what it says
    “Celecoxib should be used at the lowest effective dose and for the shortest possible time. Prolonged use without medical supervision should be avoided as this may increase the risk of heart attacks or stroke, kidney problems and stomach ulcers.”
  7. HealthHub — Celecoxib: rare but serious side effects · read 2026-08-27
    what it says
    “Increased risk of heart attack or stroke … Increased risk of gastrointestinal bleeding (bleeding in the stomach or intestines). Signs include: Blood in the urine; Black sticky stools … coffee ground-like vomit”
  8. HealthHub — Celecoxib: what precautions should I take · read 2026-08-27
    what it says
    “You are allergic to this class of medications (i.e., NSAIDs), aspirin … or have a 'sulfa' allergy … You have a history of kidney, liver, heart problems or stroke. You have asthma. You currently have an ulcer”
  9. HealthHub — Celecoxib: what food or medication should I avoid · read 2026-08-27
    what it says
    “Diuretics (e.g. Furosemide); Oral corticosteroids (e.g. Prednisolone); Certain blood pressure medications (e.g., Captopril, Enalapril …); Certain medications to treat depression (e.g. Fluoxetine, Citalopram) … avoid taking together with other NSAIDs”
  10. UK SmPC — Celebrex 200 mg capsules (Upjohn/Viatris), section 4.2 Posology, via emc · read 2026-08-27
    what it says
    “The maximum recommended daily dose is 400 mg for all indications.”
  11. US FDA label for CELEBREX (celecoxib), section 2 Dosage and Administration, via openFDA (Viatris Specialty, effective 2024-11-22) · read 2026-08-27
    what it says
    “OA: 200 mg once daily or 100 mg twice daily … RA: 100 mg to 200 mg twice daily … AP and PD: 400 mg initially, followed by 200 mg dose if needed on first day.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.