{"ok":true,"entry":{"slug":"celecoxib","kind":"medication","name":"celecoxib","aliases":["Celebrex"],"brands_sg":["Celebrex","Celecoxib Sandoz","Hovid-Celecoxib","Estacoxib","Aclexa"],"class":"COX-2 selective NSAID","tags":["pain-fever"],"use_for":"healthhub: pain and inflammation, e.g. in arthritis","use_after":"healthhub: with or without food, as prescribed","use_duration":null,"take_with":"water · healthhub: not alongside other nsaids","pros":["healthhub: for osteoarthritis, ra and acute pain","healthhub: may be taken with or without food","hh: can be taken as needed for short-term use"],"cons":["hh: higher blood pressure, swollen ankles, gut upset","hh: prolonged unsupervised use raises heart/stroke risk","hh: stomach or gut bleeding is a rare, serious risk"],"dose_note":"the uk celebrex label states 'The maximum recommended daily dose is 400 mg for all indications'. the us label's highest listed regimens match that ceiling for regular use — 'RA: 100 mg to 200 mg twice daily' — while allowing more on day one of acute pain: '400 mg initially, followed by 200 mg dose if needed on first day'. healthhub adds that it 'should be used at the lowest effective dose and for the shortest possible time'. sg-registered strengths are 100, 200 and 400 mg capsules.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["nsaid or aspirin allergy, or a 'sulfa' allergy (healthhub)","past kidney, liver or heart problems, or stroke (healthhub)","current stomach or intestinal ulcer or bleeding (healthhub)","asthma, pregnancy or breastfeeding (healthhub)"],"clashes":[{"src":["hh_cel_int"],"note":"healthhub: celecoxib is an nsaid, so the combination is to be avoided","with":"other nsaids (ibuprofen, diclofenac)"},{"src":["hh_cel_int"],"note":"healthhub: listed as an interacting medication","with":"diuretics such as furosemide"},{"src":["hh_cel_int"],"note":"healthhub: listed as interacting blood pressure medications","with":"ace inhibitors and arbs (enalapril, losartan)"},{"src":["hh_cel_int"],"note":"healthhub: listed as interacting medications","with":"ssri antidepressants (fluoxetine, citalopram)"},{"src":["hh_cel_int"],"note":"healthhub: listed as an interacting medication","with":"oral corticosteroids such as prednisolone"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 14 registered celecoxib products carry 'Prescription Only' — SIN11240P/SIN11241P/SIN13653P CELEBREX CAPSULES 100 mg, 200 mg, 400MG · Celecoxib Sandoz 200mg · HOVID-CELECOXIB 200MG · Estacoxib 200mg · ACLEXA 200MG","accessed":"2026-08-27"},{"id":"hh_cel_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub (National Medication Information workgroup, SG) — Celecoxib: what is this medication for","quote":"Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and reduce inflammation (redness, swelling and soreness) … Osteoarthritis … Rheumatoid arthritis … Ankylosing spondylitis … Acute pain conditions","accessed":"2026-08-27"},{"id":"hh_cel_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: how should I take this medication","quote":"You may take this medication with or without food. Follow the instructions on your medication label and take this medication as prescribed by your doctor.","accessed":"2026-08-27"},{"id":"hh_cel_missed","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: if you forget a dose","quote":"Celecoxib can be taken on as needed basis for short term use as prescribed by the doctor … Do not double your dose or use extra medication to make up for the missed dose.","accessed":"2026-08-27"},{"id":"hh_cel_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: common side effects","quote":"Increase in blood pressure; Fluid build up with swollen ankles, legs and/or hands; Stomach discomfort/irritation e.g. stomach pain, diarrhoea","accessed":"2026-08-27"},{"id":"hh_cel_risk","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: precautions on dose and duration","quote":"Celecoxib should be used at the lowest effective dose and for the shortest possible time. Prolonged use without medical supervision should be avoided as this may increase the risk of heart attacks or stroke, kidney problems and stomach ulcers.","accessed":"2026-08-27"},{"id":"hh_cel_rare","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: rare but serious side effects","quote":"Increased risk of heart attack or stroke … Increased risk of gastrointestinal bleeding (bleeding in the stomach or intestines). Signs include: Blood in the urine; Black sticky stools … coffee ground-like vomit","accessed":"2026-08-27"},{"id":"hh_cel_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: what precautions should I take","quote":"You are allergic to this class of medications (i.e., NSAIDs), aspirin … or have a 'sulfa' allergy … You have a history of kidney, liver, heart problems or stroke. You have asthma. You currently have an ulcer","accessed":"2026-08-27"},{"id":"hh_cel_int","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/celecoxib","label":"HealthHub — Celecoxib: what food or medication should I avoid","quote":"Diuretics (e.g. Furosemide); Oral corticosteroids (e.g. Prednisolone); Certain blood pressure medications (e.g., Captopril, Enalapril …); Certain medications to treat depression (e.g. Fluoxetine, Citalopram) … avoid taking together with other NSAIDs","accessed":"2026-08-27"},{"id":"emc_celebrex_max","url":"https://www.medicines.org.uk/emc/product/2945/smpc","label":"UK SmPC — Celebrex 200 mg capsules (Upjohn/Viatris), section 4.2 Posology, via emc","quote":"The maximum recommended daily dose is 400 mg for all indications.","accessed":"2026-08-27"},{"id":"fda_celebrex_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22CELEBREX%22&limit=1","label":"US FDA label for CELEBREX (celecoxib), section 2 Dosage and Administration, via openFDA (Viatris Specialty, effective 2024-11-22)","quote":"OA: 200 mg once daily or 100 mg twice daily … RA: 100 mg to 200 mg twice daily … AP and PD: 400 mg initially, followed by 200 mg dose if needed on first day.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:14.713299+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}