Bacopa monnieri

“the existing clinical trials show that the use of BM is promising in many brain disorders, there is still an urgent need for new studies that can define better doses … possible adverse events, or drug interactions”

“a wide range of doses were used (from 150 to 640 mg), and the duration of the treatment ranged from four weeks to six months”

“the included studies presented a small sample size, and some did not use a blinded investigation or comparison with a placebo”

“the use by humans can be related to some adverse events (side effects) such as diarrhea, nausea, increased stool frequency, abdominal cramps, stomachache … headache, dizziness, anxiety, insomnia, dry mouth, increased appetite”

“the most common clinical adverse events are mild gastrointestinal complaints, but long-term randomized clinical trials are still necessary to achieve secure doses and reduce adverse events”

“no modifications in laboratory parameters were found along with the intervention studies”

“According to Aguiar and Borowski, the standard experimental doses in humans are between 150 and 3000 mg daily”

“the optimal dose, frequency, and duration of BM administration have not been clearly established”

“The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list [Bacopa monnieri / brahmi not listed in Annex A or B]”

“Bacopa Extract, 320 mg, 120 Veggie Capsules … Bacopa Monnieri, 120 Capsules (500 mg per Capsule) … Bacopa, 320 mg, 60 Veggie Caps … Organic Bacopa, 60 Caplets … Bacopa, 500 mg, 90 Vegetarian Capsules”