← All medications

Azelastine

Medication nasal antihistamine allergy
Aka: Dymista (with fluticasone)
Brands seen in Singapore: Dymista, Synaze
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
SG label: moderate to severe allergic rhinitis
When to take
SG label: one spray in each nostril twice daily
Take with
Nasal route only · SG label: shake and prime the bottle
Pros & cons
Pros
  • SG label: suitable for long-term use, no duration limit
  • SG label: no dose change in renal impairment
  • SG label: for adults and children 6 years and older
Cons
  • HSA: no azelastine-only product is registered in SG
  • US otc label: drowsiness and a bitter taste can occur
  • The two SG products add a steroid and need a script
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (never re-fetched), 2 azelastine rows, 27 Aug 2026 · read 2026-08-27
    what it says
    “DYMISTA NASAL SPRAY (SIN15255P) and SYNAZE NASAL SPRAY (SIN15256P) both read "Prescription Only", ATC R01AD58, active ingredients "Azelastine hydrochloride&&Fluticasone propionate" 0.1 %w/w&&0.0365 %w/w; no azelastine-only product is listed”
  2. MOH National Drug Formulary — DYMISTA NASAL SPRAY [SIN15255P], Product information block · read 2026-08-27
    what it says
    “AZELASTINE HYDROCHLORIDE - 0.1% W/W; FLUTICASONE PROPIONATE - 0.0365% W/W … Forensic Classification: PRESCRIPTION ONLY MEDICINES · ATC code R01AD58 · Prescription-only Medicines with Exemptions for Supply without Prescription: NA”
  3. MOH National Drug Formulary — DYMISTA NASAL SPRAY [SIN15255P], Indications · read 2026-08-27
    what it says
    “Symptomatic treatment of moderate to severe allergic rhinitis and rhino-conjunctivitis in adults and children 6 years and older where use of a combination (intranasal antihistamine and glucocorticoid) is appropriate.”
  4. MOH National Drug Formulary — DYMISTA NASAL SPRAY [SIN15255P], Dosage and administration · read 2026-08-27
    what it says
    “One spray in each nostril twice daily (morning and evening) … not recommended for use in children below 6 years of age … suitable for long-term use. There is no restriction regarding duration of use.”
  5. US FDA OTC Drug Facts (DailyMed/openFDA) — Astepro Allergy azelastine HCl 205.5 mcg per spray, Purpose and Uses · read 2026-08-27
    what it says
    “Purpose: Antihistamine. Uses: temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: nasal congestion; runny nose; sneezing; itchy nose”
  6. US FDA OTC Drug Facts (DailyMed/openFDA) — Astepro Allergy azelastine HCl 205.5 mcg per spray, Directions · read 2026-08-27
    what it says
    “adults and children 12 years and older: … do not use more than 4 sprays in each nostril in a 24 hour period; children under 6 years: do not use”
  7. US FDA OTC Drug Facts (DailyMed/openFDA) — Astepro Allergy azelastine HCl 205.5 mcg per spray, Warnings · read 2026-08-27
    what it says
    “Ask a doctor before use if you have had recent nose ulcers or nose surgery … drowsiness may occur; avoid alcoholic drinks; alcohol, sedatives, and tranquilizers may increase drowsiness … you may get a bitter taste”
  8. NHS — Antihistamines (conditions A–Z), types and forms · read 2026-08-27
    what it says
    “Antihistamines block the effects of a substance called histamine in your body … They also come in several different forms – including tablets, capsules, liquids, syrups, creams, lotions, gels, eyedrops and nasal sprays.”
  9. NHS — Antihistamines: taking antihistamines with other medicines, food or alcohol · read 2026-08-27
    what it says
    “Examples of medicines that could cause problems if taken with antihistamines include some types of: antidepressants; stomach ulcer or indigestion medicines; cough and cold remedies that also contain an antihistamine”
  10. MOH National Drug Formulary — DYMISTA NASAL SPRAY [SIN15255P], Method of administration · read 2026-08-27
    what it says
    “DYMISTA Nasal Spray is for administration by the nasal route only. Shake the bottle gently before each use for about 5 seconds … must be primed by pressing down and releasing the pump 6 times”
  11. MOH National Drug Formulary — DYMISTA NASAL SPRAY [SIN15255P], Dosing in special populations · read 2026-08-27
    what it says
    “No dose adjustment is required in patients with renal impairment or mild to moderate hepatic impairment … Caution is required when treating patients with severe hepatic impairment”
Report a correction View as JSON

Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.