Arginine
Supplement
amino acid
fitnessheart & metabolic
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Marketed for blood flow — ODS finds little to no effect
When to take
No timing evidence to point to — ODS reports daily dosing
Take with
Water · larger doses are split across three servings
Pros & cons
Pros
- A substrate the body uses to make creatine
- Doses of 2–10 g a day are common in trials
Cons
- ODS: little to no effect on blood flow or vasodilation
- Little evidence it raises muscle creatine content
- Diarrhea and nausea reported at higher doses
Sources
- NIH ODS — Dietary Supplements for Exercise and Athletic Performance (Health Professional) · read 2026-08-27
what it says
“Increases blood flow and delivery of oxygen and nutrients to skeletal muscle; serves as a substrate for creatine production … Little to no effect on vasodilation, blood flow, or exercise metabolites … diarrhea and nausea”
- HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025, Annex A/B) · read 2026-08-27
what it says
“Annex B: List of substances with potential safety issues and recommended risk mitigation measures”
- HSA — Guidelines on health supplements (Tables 4–5, maximum daily dose limits) · read 2026-08-27
what it says
“Table 4: Vitamins Limits … Table 5: Minerals Limits”
- iHerb Singapore — L-Arginine category (default order) · read 2026-08-27
what it says
“California Gold Nutrition … NOW Foods … Nutricost … EVLution Nutrition … Force Factor”
Updated 2026-08-30. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.