{"ok":true,"entry":{"slug":"arginine","kind":"supplement","name":"arginine","aliases":["L-arginine","AAKG"],"brands_sg":["California Gold Nutrition","NOW Foods","Nutricost","EVLution Nutrition","Force Factor"],"class":"amino acid","tags":["fitness","heart"],"use_for":"marketed for blood flow — ODS finds little to no effect","use_after":"no timing evidence to point to — ODS reports daily dosing","use_duration":null,"take_with":"water · larger doses are split across three servings","pros":["a substrate the body uses to make creatine","doses of 2–10 g a day are common in trials"],"cons":["ODS: little to no effect on blood flow or vasodilation","little evidence it raises muscle creatine content","diarrhea and nausea reported at higher doses"],"dose_note":"the ODS sheet reports most common doses of 2–10 g a day as a single dose and up to 20 g a day divided into three doses, alongside little to no measured effect on blood flow","dosage":{"ul":null,"unit":"g","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["on blood-pressure medicines — it is used for a blood-flow effect; ask your doctor first","gastrointestinal upset — diarrhea and nausea reported at higher doses","20 g a day sits at the top of the studied range"],"clashes":[],"sources":[{"id":"ods_eap","url":"https://ods.od.nih.gov/factsheets/ExerciseAndAthleticPerformance-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Exercise and Athletic Performance (Health Professional)","quote":"Increases blood flow and delivery of oxygen and nutrients to skeletal muscle; serves as a substrate for creatine production … Little to no effect on vasodilation, blood flow, or exercise metabolites … diarrhea and nausea","accessed":"2026-08-27"},{"id":"hsa_restricted","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025, Annex A/B)","quote":"Annex B: List of substances with potential safety issues and recommended risk mitigation measures","accessed":"2026-08-27"},{"id":"hsa_hs","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Guidelines on health supplements (Tables 4–5, maximum daily dose limits)","quote":"Table 4: Vitamins Limits … Table 5: Minerals Limits","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/l-arginine","label":"iHerb Singapore — L-Arginine category (default order)","quote":"California Gold Nutrition … NOW Foods … Nutricost … EVLution Nutrition … Force Factor","accessed":"2026-08-27"}],"brand_certs":[{"brand":"Force Factor","example":null,"programme":"NSF Certified for Sport","matching_products":0,"brand_total_certified":6}],"updated_at":"2026-08-30T17:59:38.376296+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}