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Agaricus

Supplement mushroom immune
Aka: Agaricus blazei, royal sun agaricus
Brands seen in Singapore: California Gold Nutrition, Quality of Life, Yerba Prima, Swanson Vitamins, Paradise Herbs
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Limited human evidence — one pilot trial in patients
Studied for
The pilot trial ran 28 days after surgery
Pros & cons
Pros
  • A 66-person randomized double-blind pilot exists
  • T and b cell counts held up better than placebo
Cons
  • The product tested was a multivitamin, not agaricus
  • The main nk-activity outcome missed significance
  • Case report: liver injury linked to agaricus powder
Sources
  1. Immunomodulatory Effects of Multivitamin Complexes Containing Agaricus blazei in Patients Undergoing Curative Resection for Non-Small-Cell Lung Cancer (Biomedicines 2025) — design · read 2026-08-27
    what it says
    “In this randomized, double-blind, placebo-controlled multicenter pilot trial, 66 patients with stage I-III NSCLC received either a supplement or a placebo for 28 days post-surgery.”
  2. Agaricus blazei multivitamin pilot trial, Biomedicines 2025 — results · read 2026-08-27
    what it says
    “Although the increase in NKA was not statistically significant, the treatment group showed a greater relative recovery (17.8% vs. 9.9%, p = 0.104). Immune profiling demonstrated significantly better preservation of T cells and B cells”
  3. Agaricus blazei multivitamin pilot trial, Biomedicines 2025 — what was actually tested · read 2026-08-27
    what it says
    “This study aimed to evaluate whether multivitamin and mineral complexes containing Agaricus blazei could support postoperative immune recovery.”
  4. Grade 3 cytolysis in a patient with metastatic colorectal cancer consuming a mushroom powder-based alternative therapy (J Oncol Pharm Pract 2025) · read 2026-08-27
    what it says
    “Here, we report a case of cytolysis and hepatic cholestasis in a patient who was self-medicated with a mushroom powder-based alternative therapy containing Agaricus blazei Murril (ABM) during cancer treatment.”
  5. Agaricus blazei hepatic cytolysis case report, J Oncol Pharm Pract 2025 — attribution · read 2026-08-27
    what it says
    “given the improvement in liver function after CAM discontinuation, hepatic cytolysis appeared to be linked to ABM consumption despite the patient's liver metastases”
  6. HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025), Annex A/B — searched, no row for this ingredient · read 2026-08-27
    what it says
    “The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
  7. iHerb Singapore — Agaricus category (default order, 10 results); first 5 distinct brands: California Gold Nutrition, Quality of Life, Yerba Prima, Swanson Vitamins, Paradise Herbs · read 2026-08-27
    what it says
    “California Gold Nutrition, Fungiology, MushRex Plus … Quality of Life, Deodorex® with Champex® Mushroom Extract … Yerba Prima, Odor Cleanse … Swanson Vitamins, Agaricus Blazei Mushroom Extract, 500 mg … Paradise Herbs, Beta Glucans”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.