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Vilanterol

Medication long-acting beta-2 agonist respiratory
Aka: Relvar
Brands seen in Singapore: Relvar Ellipta, Anoro Ellipta, Trelegy Ellipta
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Regular asthma or copd control, never on its own
When to take
SG label: one inhalation once daily, SAMe time each day
Take with
An inhaled steroid · SG registers no vilanterol-only inhaler
Pros & cons
Pros
  • SG label: once-daily dosing, morning or evening
  • SG label: relvar 100/25 is the strength used in copd
  • US label: a reliever still covers between-dose symptoms
Cons
  • US label: laba alone raises asthma-death risk
  • US label: not for relief of acute bronchospasm
  • US label: tremor and heart effects follow beta-2 dosing
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 5 vilanterol rows read 'Prescription Only' and every one is a fixed combination — RELVAR ELLIPTA 100/25 and 200/25 (with fluticasone furoate) · ANORO ELLIPTA 62.5/25 (with umeclidinium) · TRELEGY ELLIPTA 100/62.5/25 and 200/62.5/25”
  2. National Drug Formulary (SG, MOH) — RELVAR ELLIPTA INHALATION POWDER 100MCG/25MCG [SIN14736P], indications and dosing, last updated 28 Jul 2026 · read 2026-08-27
    what it says
    “indicated for the regular treatment of asthma in adults and adolescents aged 12 years and older where use of a combination medicinal product (long-acting beta 2-agonist and inhaled corticosteroid) is appropriate … administered once daily either morning or evening”
  3. National Drug Formulary (SG, MOH) — TRELEGY ELLIPTA INHALATION POWDER 100/62.5/25 MCG [SIN15806P], Dosage and Administration · read 2026-08-27
    what it says
    “The maximum recommended dosage is 1 inhalation of Trelegy Ellipta 200/62.5/25 mcg once daily … Trelegy Ellipta should be used at the same time every day. Do not use Trelegy Ellipta more than 1 time every 24 hours.”
  4. US FDA label — BREO ELLIPTA (fluticasone furoate and vilanterol, GSK), section 1 Indications and Usage, via openFDA (effective 7 Nov 2024) · read 2026-08-27
    what it says
    “a combination of fluticasone furoate, a corticosteroid, and vilanterol, a long-acting beta2-adrenergic agonist (LABA) … Limitations of Use: Not indicated for relief of acute bronchospasm”
  5. US FDA label — BREO ELLIPTA, section 2 Dosage and Administration, via openFDA · read 2026-08-27
    what it says
    “The maximum recommended dosage is 1 inhalation of BREO ELLIPTA 200/25 mcg once daily … If shortness of breath occurs in the period between doses, an inhaled, short-acting beta2-agonist (rescue medicine, e.g., albuterol) should be used”
  6. US FDA label — BREO ELLIPTA, section 5 Warnings and Precautions, via openFDA · read 2026-08-27
    what it says
    “LABA monotherapy increases the risk of serious asthma-related events … Do not use in combination with additional therapy containing a LABA because of risk of overdose … Use with caution in patients with cardiovascular disorders because of beta-adrenergic stimulation”
  7. US FDA label — BREO ELLIPTA, section 7 Drug Interactions, via openFDA · read 2026-08-27
    what it says
    “Strong cytochrome P450 3A4 inhibitors (e.g., ketoconazole): Use with caution … Monoamine oxidase inhibitors and tricyclic antidepressants: Use with extreme caution … Beta-blockers: … may block bronchodilatory effects … Diuretics: … hypokalemia … may worsen”
  8. US FDA label — ANORO ELLIPTA (umeclidinium and vilanterol, GSK), section 2 Dosage and Administration, via openFDA (effective 2 Jun 2023) · read 2026-08-27
    what it says
    “The recommended dosage of ANORO ELLIPTA for maintenance treatment of COPD is 62.5 mcg umeclidinium and 25 mcg vilanterol … once daily by oral inhalation … Do not use ANORO ELLIPTA more than 1 time every 24 hours.”
  9. US FDA label — ANORO ELLIPTA, section 4 Contraindications, via openFDA · read 2026-08-27
    what it says
    “use of a long-acting beta2-adrenergic agonist (LABA), including vilanterol … without an inhaled corticosteroid (ICS), in patients with asthma … Severe hypersensitivity to milk proteins or any ingredients … Not indicated for the treatment of asthma”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.