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Tirzepatide

Medication GIP/GLP-1 receptor agonist diabetes
Aka: Mounjaro, Zepbound
Brands seen in Singapore: Mounjaro
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Type 2 diabetes in adults, alongside diet and exercise
When to take
Once a week, any time of day, with or without meals
Take with
Injected under the skin of the abdomen, thigh or upper arm
Pros & cons
Pros
  • SG label: one injection a week, any time of day
  • SG label: no dose change for renal or liver impairment
  • SG label: a missed dose has a 4-day catch-up window
Cons
  • The SG licence covers type 2 diabetes, not weight loss
  • NHS: nausea, vomiting and bowel changes are common
  • NHS: acute pancreatitis and gallstones are rare risks
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally, 27 Aug 2026 · read 2026-08-27
    what it says
    “MOUNJARO INJECTION 5MG/0.5ML SIN16714P | Tirzepatide | Prescription Only | A10BX16; MOUNJARO KwikPen SIN17257P–SIN17262P; MOUNJARO SOLUTION FOR INJECTION IN VIAL SIN17351P–SIN17356P — all 18 tirzepatide rows 'Prescription Only'; no ZEPBOUND row exists”
  2. MOH National Drug Formulary (Singapore) — MOUNJARO INJECTION 5MG/0.5ML [SIN16714P], product information and forensic classification · read 2026-08-27
    what it says
    “TIRZEPATIDE - 5 MG/0.5 ML … Registration Number SIN16714P … Licence Holder DKSH SINGAPORE PTE. LTD. … Forensic Classification PRESCRIPTION ONLY MEDICINES … ATC code A10BX16 … Prescription-only Medicines with Exemptions for Supply without Prescription: NA”
  3. MOH National Drug Formulary (Singapore) — MOUNJARO [SIN16714P], 4.1 Therapeutic indications · read 2026-08-27
    what it says
    “Mounjaro is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise … in addition to other medicinal products for the treatment of diabetes”
  4. MOH National Drug Formulary (Singapore) — MOUNJARO [SIN16714P], 4.2 Posology: maintenance and maximum dose · read 2026-08-27
    what it says
    “The starting dose of tirzepatide is 2.5 mg once weekly … The recommended maintenance doses are 5 mg, 10 mg and 15 mg. The maximum dose is 15 mg once weekly”
  5. MOH National Drug Formulary (Singapore) — MOUNJARO [SIN16714P], 4.2 Posology: combination with a sulphonylurea or insulin · read 2026-08-27
    what it says
    “When tirzepatide is added to existing therapy of a sulphonylurea and/or insulin, a reduction in the dose of sulphonylurea or insulin may be considered to reduce the risk of hypoglycaemia”
  6. MOH National Drug Formulary (Singapore) — MOUNJARO [SIN16714P], 4.2 Method of administration and missed doses · read 2026-08-27
    what it says
    “Mounjaro is to be injected subcutaneously in the abdomen, thigh or upper arm. The dose can be administered at any time of day, with or without meals. Injection sites should be rotated with each dose”
  7. MOH National Drug Formulary (Singapore) — MOUNJARO [SIN16714P], 4.2 Special populations and missed doses · read 2026-08-27
    what it says
    “No dose adjustment is required for patients with renal impairment including end stage renal disease (ESRD) … No dose adjustment is required for patients with hepatic impairment”
  8. MOH National Drug Formulary (Singapore) — MOUNJARO [SIN16714P], 4.2 Posology: missed doses · read 2026-08-27
    what it says
    “If a dose is missed, it should be administered as soon as possible within 4 days after the missed dose. If more than 4 days have passed, skip the missed dose”
  9. NHS medicines A–Z — Tirzepatide (common brands: Mounjaro), page last reviewed 15 May 2026 · read 2026-08-27
    what it says
    “Tirzepatide is a type of medicine called a GLP-1/GIP agonist … It's only available with a prescription … Tirzepatide comes as an injection that you use once a week … you can have it any time of day”
  10. NHS medicines A–Z — Tirzepatide, side effects and who cannot use it · read 2026-08-27
    what it says
    “Common side effects of tirzepatide include: feeling sick (nausea) or being sick (vomiting), constipation or diarrhoea, stomach pain … an inflamed pancreas (acute pancreatitis) … gallstones or swelling of the gallbladder”
  11. NHS medicines A–Z — Tirzepatide, using it with other medicines, food and drink · read 2026-08-27
    what it says
    “other diabetes medicines, such as gliclazide, glimepiride, metformin and tolbutamide; some medicines to prevent blood clots, such as warfarin; insulin … a general anaesthetic … or a sedative … It's best to avoid drinking alcohol”
  12. NHS medicines A–Z — Tirzepatide, pregnancy, breastfeeding and contraception · read 2026-08-27
    what it says
    “Tirzepatide is not used during pregnancy … If you want to become pregnant, you should stop using tirzepatide at least 4 weeks before you start trying … It's important to use an additional barrier contraception … for 4 weeks after starting”

Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.