Pau d'arco
Supplement
botanical
immune
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Traditional use for fever and infections — evidence is thin
When to take
Daily
Studied for
The one human trial ran eight weeks
Pros & cons
Pros
- Small trial reported no serious adverse events
- Long traditional record in south america
Cons
- 9 of 12 in that trial reported an adverse event
- No placebo arm in the one human trial
- The trial used T. avellanedae, a related species
Sources
- Tabebuia impetiginosa: a comprehensive review on traditional uses, phytochemistry, and immunopharmacological properties (Molecules, 2020) · read 2026-08-27
what it says
“Tabebuia impetiginosa, a plant native to the Amazon rainforest … is traditionally used for treating fever, malaria, bacterial and fungal infections, and skin diseases … Further scientific evidence is required for clinical trials on its immunopharmacological effects and safety.”
- Safety and tolerability of pau d'arco (Tabebuia avellanedae) for primary dysmenorrhea: single-arm, open-label trial (Adv Integr Med, 2022) · read 2026-08-27
what it says
“A single arm, open-label trial … 1050 mg/day of encapsulated Tabebuia avellanedae (Pau d'Arco) was administered to twelve healthy women aged 18-45 for eight weeks … Seventy-five percent of study participants (n = 9/12) reported an adverse event”
- HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B · read 2026-08-27
what it says
“The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.”
- iHerb Singapore — Pau D'Arco category page (default best-selling order) · read 2026-08-27
what it says
“Pau D'Arco”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.