Paracetamol
Medication
analgesic · antipyretic
pain & fever
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Relief of fever, headache, body aches and general pain
When to take
Label: every 4–6 h as needed · at least 4 h between doses
Take with
With or without food
Pros & cons
Pros
- Well tolerated with few reported side effects
- Can be taken with or without food
- General sale list in SG (panadol, tylenol)
Cons
- Over the label max can seriously harm the liver
- Doubling up risk — cold/flu medicines may contain it
- Regular alcohol use? check with a doctor first
Sources
- HealthHub (MOH Singapore) — Paracetamol (Oral), article last reviewed 08 July 2026 · read 2026-08-27
what it says
“Paracetamol (also known as Acetaminophen) is used to relieve fever, headache, body aches and pain in general … please make sure to take it as recommended on the label. Do not take two products containing Paracetamol at the same time … Paracetamol can be taken with or without food … Inform your healthcare professional if … You have liver disease or regularly drink large quantities of alcohol … You have kidney disease … Paracetamol is well tolerated with few reported side effects … Check with your healthcare professional before taking Paracetamol if you are taking Warfarin or other similar medications to prevent blood clots”
- Panadol (paracetamol 500 mg caplet) — Singapore patient leaflet, Haleon, GDS v7.0, last updated August 2025 (approving market: Singapore) · read 2026-08-27
what it says
“Panadol is indicated as an effective analgesic and antipyretic for the fast relief of fever and painful conditions such as headache, migraine, backache, joint and muscle pain, period pain (dysmenorrhea), toothache … and sore throat … Do not take more frequently than every 4 hours. Do not take more than 8 caplets per day … Adults and children over 12 years: 1-2 caplets taken every 4 to 6 hours as required … Do not take more than the recommended dose as it may cause serious harm to your liver. Do not use this medicine if you are taking any other prescription or non-prescription medicines containing paracetamol … Check with your doctor before use if: You have liver or kidney problems. You are underweight or malnourished. You regularly drink alcohol … Talk to your health care professional before taking paracetamol if you are pregnant … consult your doctor if you are taking warfarin or similar medicines used to thin the blood”
- NHS medicines A–Z — Paracetamol for adults · read 2026-08-27
what it says
“Paracetamol is a painkiller that can be used to treat: headaches, joint swelling and stiffness, symptoms of a cold or flu, such as a high temperature (fever), toothache, sore throat … You can take tablets or capsules with or without food. For 500mg tablets and capsules: one dose is 1 or 2 tablets or capsules, leave at least 4 hours between each dose, do not take more than 8 tablets or capsules in 24 hours … if you weigh less than 50kg, you may need to take a lower dose … it may not be suitable if … you have a kidney or liver condition, you're dependent on alcohol or binge drink … Paracetamol very rarely causes side effects if you take it correctly … medicines … that may not mix well with paracetamol … other medicine containing paracetamol, such as cold and flu medicine, medicines that stop you being sick, including metoclopramide and domperidone, medicines to help prevent blood clots, such as warfarin, an antibiotic called flucloxacillin … Adults can take paracetamol at the same time as ibuprofen if needed”
- FDA DailyMed — Tylenol Extra Strength (acetaminophen 500 mg) Drug Facts label, Kenvue Brands LLC, setid 103d109d-f520-409c-8da2-eb6b0fbec891 · read 2026-08-27
what it says
“temporarily relieves minor aches and pains … temporarily reduces fever … Liver warning … Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, 3 or more alcoholic drinks every day while using this product … Do not use with any other drug containing acetaminophen … Ask a doctor before use if you have liver disease. Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin … If pregnant or breast-feeding, ask a health professional before use … take 2 caplets every 6 hours while symptoms last, do not take more than 6 caplets in 24 hours, unless directed by a doctor”
- HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, managed by Health Sciences Authority, last updated 7 Aug 2026), Forensicclassification column · read 2026-08-27
what it says
“PANADOL TABLET 500 mg | SIN05919P | General Sale List; TYLENOL FILM COATED TABLETS 500MG | SIN15949P | General Sale List — all 47 single-ingredient oral paracetamol products in the register carry Forensicclassification = General Sale List (pulled via datastore_search API, 27 Aug 2026)”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.