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Magnesium hydroxide

Medication antacid / osmotic laxative digestive
Aka: milk of magnesia
Brands seen in Singapore: Hydrosil, Macgel, Axcel Eviline, Actal Plus
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Heartburn and indigestion · constipation at laxative doses
When to take
After meals or when symptoms arise (SG antacid label)
Take with
Water · a full glass with each laxative dose (US label)
Pros & cons
Pros
  • Laxative doses act in ½ to 6 hours (US label)
  • General sale list in Singapore — no prescription
  • SG antacid strengths are small: 200 mg or 400 mg/5 ml
Cons
  • Kidney disease — US label says ask a doctor first
  • Magnesium-restricted diet — label says ask first
  • Binds other medicines — labels ask for 2 h+ spacing
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows; filtered locally for magnesium hydroxide) · read 2026-08-27
    what it says
    “Forensicclassification = 'General Sale List' for all 5 magnesium-hydroxide rows: SIN03484P HYDROSIL TABLET; SIN08119P MACGEL TABLET; SIN06592P AXCEL EVILINE TABLET; SIN06400P AXCEL EVILINE FORTE SUSPENSION; SIN07376P ACTAL PLUS TABLET”
  2. MOH National Drug Formulary — HYDROSIL TABLET [SIN03484P], product information · read 2026-08-27
    what it says
    “ALUMINIUM HYDROXIDE (DRIED GEL) - 200 MG MAGNESIUM HYDROXIDE - 200 MG SIMETHICONE - 20 MG … Forensic Classification GENERAL SALE LIST”
  3. MOH National Drug Formulary — AXCEL EVILINE FORTE SUSPENSION [SIN06400P], indications · read 2026-08-27
    what it says
    “Eviline Forte is an antacid / deflatulent for symptomatic treatment of peptic ulcer, dyspepsia of functional or organic origin, heartburn in hiatus hernia or pregnancy, flatulence and abdominal distension”
  4. MOH National Drug Formulary — AXCEL EVILINE FORTE SUSPENSION [SIN06400P], dosage and administration · read 2026-08-27
    what it says
    “For oral administration only. One 5ml spoonful to be taken after meals or whenever symptoms arise.”
  5. FDA DailyMed — MILK OF MAGNESIA oral suspension (Strategic Sourcing Services LLC), OTC label eff. 2023-11-08 · read 2026-08-27
    what it says
    “Purpose Saline laxative … Uses relieves occasional constipation (irregularity) generally produces bowel movement in 1/2 to 6 hours”
  6. FDA DailyMed — MILK OF MAGNESIA, Directions · read 2026-08-27
    what it says
    “do not exceed the maximum recommended daily dose in a 24 hour period … drink a full glass (8 oz) of liquid with each dose … adults and children 12 years and over 30 mL to 60 mL”
  7. FDA DailyMed — MILK OF MAGNESIA, Warnings · read 2026-08-27
    what it says
    “Ask a doctor before use if you have kidney disease a magnesium-restricted diet … Ask a doctor or pharmacist before use if you are presently taking a prescription drug … If pregnant or breast-feeding, ask a health professional”
  8. HealthHub (National Medication Information workgroup) — Levofloxacin: what food or medication should I avoid, reviewed 31 May 2024 · read 2026-08-27
    what it says
    “Indigestion remedies (e.g. Antacids) … You should take the above products 2 hours before or after Levofloxacin as taking them together reduces the absorption of Levofloxacin into your body.”
  9. MOH National Drug Formulary — CRAVIT TABLET 500 MG [SIN11632P], dosage and administration · read 2026-08-27
    what it says
    “Oral doses should be administered at least two hours before or two hours after antacids containing magnesium, aluminum, as well as sucralfate, metal cations such as iron”
  10. FDA DailyMed — Moxifloxacin hydrochloride tablets (A-S Medication Solutions), Drug Interactions, eff. 2024-09-18 · read 2026-08-27
    what it says
    “Multivalent cation-containing products including: antacids, sucralfate, multivitamins Decreased moxifloxacin hydrochloride absorption. Take moxifloxacin tablet at least 4 hours before or 8 hours after these products.”
  11. FDA DailyMed — Cefuroxime axetil tablets (A-S Medication Solutions), Drug Interactions, eff. 2025-10-08 · read 2026-08-27
    what it says
    “Administer cefuroxime axetil at least 1 hour before or 2 hours after administration of short-acting antacids. Histamine-2 (H2) antagonists and proton pump inhibitors should be avoided.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.