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Furosemide

Medication loop diuretic heart & blood pressure
Aka: frusemide, Lasix
Brands seen in Singapore: Dirine, Fusix, Furmide, Fusetic, Rasitol
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for fluid build-up, and for high blood pressure
When to take
NHS: usually once a day, ideally in the morning
Take with
Water · NHS: with or without food
Pros & cons
Pros
  • NHS: with or without food, usually once a day
  • HealthHub: sheds extra water and salts via the kidneys
  • SG register: 40 mg tablets and 20 mg/2 ml injections
Cons
  • NHS: peeing more, thirst, dizziness, headaches
  • HealthHub: can lower potassium in the blood
  • FDA: tinnitus and hearing loss have been reported
Sources
  1. HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally) · read 2026-08-27
    what it says
    “All 9 registered furosemide/frusemide products read Forensicclassification 'Prescription Only' — SIN00239P DIRINE INJECTION 20 mg/2 ml · SIN11748P FUSIX TABLET 40 mg · SIN00064P FURMIDE TABLETS 40 mg · SIN16712P FUSETIC · SIN14074P RASITOL TABLET 40MG.”
  2. NHS Medicines A-Z — Furosemide: what furosemide is for · read 2026-08-27
    what it says
    “Furosemide is a medicine used to treat swelling caused by a build-up of fluid in the body. It can also be used for high blood pressure. It's only available on prescription … a type of medicine called a diuretic”
  3. NHS Medicines A-Z — Furosemide: how to take furosemide · read 2026-08-27
    what it says
    “try to take it at the same time each day – ideally every morning if you take it once a day … swallow tablets and capsules with water; you can take it with or without food”
  4. NHS Medicines A-Z — Furosemide: side effects · read 2026-08-27
    what it says
    “Common side effects of furosemide can include: peeing more than usual; feeling thirsty, with a dry mouth and lips (these can be signs of dehydration); dizziness; headaches; muscle twitches”
  5. NHS Medicines A-Z — Furosemide: who can and cannot take it · read 2026-08-27
    what it says
    “it may not be suitable if: … you have kidney or liver problems; you have diabetes or Addison's disease; you have or have had gout; you have low blood pressure”
  6. NHS Medicines A-Z — Furosemide: taking it with other medicines · read 2026-08-27
    what it says
    “other medicines used to treat high blood pressure, including aliskerin, beta blockers and ACE inhibitors like lisinopril; medicines used to treat heart rhythm problems, including digoxin, amiodarone, flecainide and sotalol”
  7. HealthHub (Pharmaceutical Society of Singapore) — Frusemide: what is this medication for · read 2026-08-27
    what it says
    “Frusemide belongs to a class of medications called Diuretics. It works on your kidneys to get rid of extra water and salts in your body … it may also be used to treat high blood pressure.”
  8. HealthHub — Frusemide: how should I take this medication · read 2026-08-27
    what it says
    “If you are taking one dose a day, take it in the morning. If you are taking the medication two times a day, take the second dose before 4pm”
  9. HealthHub — Frusemide: what precautions should I take · read 2026-08-27
    what it says
    “Inform your healthcare professional if: … You are allergic to any other medications, especially sulfonamide medicines (e.g. Bactrim); You are pregnant, planning to become pregnant, or breastfeeding; You have any problems with the way your kidneys work; You have gout”
  10. HealthHub — Frusemide: common side effects · read 2026-08-27
    what it says
    “Passing urine more often, dry mouth, increased thirst … Dizziness and lightheadedness … This medication may cause potassium loss … such as weakness/ tiredness, muscle cramps, loss of appetite or irregular/ fast heart beat”
  11. US FDA label — furosemide tablets, Dosage and Administration, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Adults - The usual initial dose of furosemide tablets is 20 to 80 mg given as a single dose … The dose of furosemide tablets may be carefully titrated up to 600 mg/day in patients with clinically severe edematous states”
  12. US FDA label — furosemide tablets, Warnings, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion … Cases of tinnitus and reversible or irreversible hearing impairment and deafness have been reported.”
  13. US FDA label — furosemide tablets, Precautions, via openFDA drug/label.json · read 2026-08-27
    what it says
    “Hypokalemia may develop with furosemide, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids, ACTH, licorice in large amounts, or prolonged use of laxatives.”
  14. NHS Medicines A-Z — Furosemide: taking it with other medicines (continued) · read 2026-08-27
    what it says
    “medicines or supplements that increase your potassium levels; some non-steroidal anti-inflammatory drugs (NSAIDs); medicines used to treat constipation (laxatives) … antidepressants, such as amitriptyline and sertraline … lithium (used to treat some mental health problems)”
  15. US FDA label — furosemide tablets, Dosage and Administration (pediatric patients), via openFDA drug/label.json · read 2026-08-27
    what it says
    “Pediatric Patients - The usual initial dose of oral furosemide in pediatric patients is 2 mg/kg body weight, given as a single dose … Doses greater than 6 mg/kg body weight are not recommended.”
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Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.