Amoxicillin
Medication
antibiotic (penicillin)
antibiotic
Not medical advice. Check with your doctor or pharmacist before you start, stop or change the timing of anything you take.
How to use
What it’s for
Prescribed for bacterial infections — your doctor decides
When to take
Doses spaced evenly · every 8 or 12 h as prescribed
Take with
Water · before or after food; with a meal eases the stomach
Pros & cons
Pros
- Feel better within a few days for most infections (NHS)
- Before or after food per NHS · with/after food per SG
- Alcohol allowed per NHS
Cons
- Rash, nausea or diarrhoea in up to 1 in 10 people
- Penicillin-class — allergy can be serious
- Thrush can follow a course (NHS)
Sources
- HSA — Listing of Registered Therapeutic Products (official open dataset on data.gov.sg, last updated 7 Aug 2026; same register as HSA Infosearch) · read 2026-08-27
what it says
“Forensicclassification = 'Prescription Only' for all 47 amoxicillin-containing products on the register (21 single-ingredient amoxicillin/amoxycillin, all oral; 26 amoxicillin + clavulanate, 23 oral + 3 IV) — e.g. SIN11417P STRIMOX-250 CAPSULE 250 mg · SIN09408P APO-AMOXI FOR ORAL SUSPENSION 250 mg/5 ml · SIN11190P PULMOXYL - 500 CAPSULE 500 mg · SIN13721P Promox Capsules 500mg BP · SIN14520P MOXILEN CAPSULE 500MG — all 'Prescription Only'”
- HealthHub (MOH Singapore / Pharmaceutical Society of Singapore) — Amoxicillin medication information leaflet, reviewed 8 May 2026 · read 2026-08-27
what it says
“Amoxicillin belongs to a group of antibiotics known as penicillin, and is used to treat bacterial infections … Take this medication with or after food to reduce stomach discomfort. Take this medication at regular intervals to improve antibiotic efficacy. You should complete each course of antibiotics even if you feel better … Inform your healthcare professional if: You had a previous allergic reaction to Amoxicillin, Cloxacillin, Penicillins, Cephalexin, Cefuroxime or similar antibiotics … You have kidney problems. You are pregnant, planning to become pregnant, or breastfeeding … Take this medication 2 hours apart from probiotics as the antibiotics may reduce the effectiveness of probiotics.”
- NHS Medicines A-Z — About amoxicillin (reviewed 2 June 2025) · read 2026-08-27
what it says
“Amoxicillin is a type of penicillin antibiotic. It's used to treat bacterial infections … Amoxicillin is only available on prescription … You can drink alcohol while taking amoxicillin. Some people who take antibiotics including amoxicillin can develop thrush.”
- NHS Medicines A-Z — How and when to take amoxicillin (reviewed 2 June 2025) · read 2026-08-27
what it says
“Try to space your doses evenly throughout the day … You can take amoxicillin before or after food. Swallow amoxicillin capsules whole with a drink of water … You should carry on taking amoxicillin until you've finished the course, even if you feel better. If you stop your treatment early, the infection could come back.”
- NHS Medicines A-Z — Who can and cannot take amoxicillin (reviewed 2 June 2025) · read 2026-08-27
what it says
“tell a doctor before starting to take it if you: have ever had an allergic reaction to amoxicillin or penicillin or any other medicine · have liver or kidney problems … have glandular fever – taking amoxicillin can cause a rash if you have this condition”
- NHS Medicines A-Z — Taking amoxicillin with other medicines and herbal supplements (reviewed 2 June 2025) · read 2026-08-27
what it says
“Check with a pharmacist or your doctor if you're taking any other medicines, including: methotrexate – a medicine to treat arthritis and psoriasis · warfarin – a medicine to prevent blood clots · gout medicines called probenecid or allopurinol · other antibiotics … There's not enough information to say that complementary medicines, herbal remedies and supplements are safe to take with amoxicillin.”
- NHS Medicines A-Z — Common questions about amoxicillin (reviewed 2 June 2025) · read 2026-08-27
what it says
“For most infections, you should feel better within a few days … Amoxicillin does not stop any type of contraception working, including the combined contraceptive pill, progestogen-only pill and emergency contraception. However, if amoxicillin makes you sick (vomit) or have severe, watery diarrhoea or any diarrhoea that lasts for more than 24 hours, your contraceptive pills may not protect you from pregnancy … Yes, you can drink alcohol while taking amoxicillin.”
- NHS Medicines A-Z — Side effects of amoxicillin (reviewed 2 June 2025) · read 2026-08-27
what it says
“These common side effects of amoxicillin can happen in up to 1 in 10 people who take the medicine … Skin rash … Feeling sick (nausea) … Diarrhoea”
- NHS Medicines A-Z — Pregnancy, breastfeeding and fertility while taking amoxicillin (reviewed 2 June 2025) · read 2026-08-27
what it says
“It is safe to take amoxicillin during pregnancy. Check with a pharmacist or doctor before taking it … It's OK to take amoxicillin while breastfeeding because only tiny amounts of it get into breast milk.”
- FDA DailyMed — Amoxicillin capsules / tablets / for oral suspension, USP (Sandoz Inc.) prescribing information, rev. 02/2024, SPL v26 · read 2026-08-27
what it says
“Rx Only … To minimize the potential for gastrointestinal intolerance, amoxcillin should be taken at the start of a meal … Advise patients that amoxicillin may be taken every 8 hours or every 12 hours, depending on the dose prescribed … Skipping doses or not completing the full course of therapy may: (1) decrease the effectiveness of the immediate treatment, and (2) increase the likelihood that bacteria will develop resistance … contraindicated in patients who have experienced a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to amoxicillin or to other β-lactam antibacterial drugs (e.g., penicillins and cephalosporins) … A high percentage of patients with mononucleosis who receive amoxicillin develop an erythematous skin rash … Reduce the dose in patients with severe renal impairment … 7.1 Probenecid … may result in increased and prolonged blood levels of amoxicillin. 7.2 Oral Anticoagulants: Abnormal prolongation of prothrombin time (increased international normalized ratio [INR]) has been reported in patients receiving amoxicillin and oral anticoagulants. Appropriate monitoring should be undertaken … 7.3 Allopurinol: The concurrent administration of allopurinol and amoxicillin increases the incidence of rashes … 7.4 Oral Contraceptives: Amoxicillin may affect the intestinal flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.”
Updated 2026-08-29. Every line above traces to a numbered source. Kozen-X is not a medical device and does not give medical advice. It lists what published sources have written down — nothing more. A pair not listed is unrecorded, not cleared. Before you start, stop or re-time anything, talk to your doctor or pharmacist.