{"ok":true,"entry":{"slug":"yerba-mate","kind":"supplement","name":"yerba mate","aliases":["Ilex paraguariensis"],"brands_sg":["Mate Factor","EcoTeas","Wisdom Of The Ancients","Choice Organics","The Tao of Tea"],"class":"botanical","tags":["energy"],"use_for":"a caffeine-bearing tea; therapeutic claims are unsupported","use_after":"as a daily infusion","use_duration":"human trials are short and mixed","take_with":"warm, not scalding — very hot drinking is an avoidable risk","pros":["a real caffeine source — 1%–1.5% caffeine by weight","rich in caffeoylquinic acids and methylxanthines","unsmoked leaf is among the sg listings"],"cons":["pooled rcts: no effect on bmi or waist circumference","very hot drinking and smoke-derived pahs are risks","adverse events: insomnia, tachycardia, gut upset"],"dose_note":"no single dose is established: the 13 randomised trials pooled in 2025 differed in dose and formulation, and the one 45-day weight trial ods describes used 336 mg of yerba maté (1%–1.5% caffeine) before each main meal alongside guarana and damiana; reviewers frame safe use as controlling total caffeine, beverage temperature and processing contaminants rather than hitting a dose","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["very hot serving temperature — reviewers list very-hot consumption as an avoidable risk of mate drinking","traditional smoke-dried mate — smoke-derived polycyclic aromatic hydrocarbons are named as the other avoidable risk","caffeine sensitivity or pregnancy — mate carries caffeine and hsa's annex b asks sg labels to state the amount","hsa: yerba mate / ilex paraguariensis is not listed in annex a or annex b of the oct 2025 guideline, but caffeine — its methylxanthine — is annex b item 1"],"clashes":[{"src":["hsa_caffeine_annexb","ods_caffeine_sources"],"food":true,"note":"hsa annex b asks sg labels to advise limiting concurrent caffeine-containing products and to state the caffeine amount","with":"other caffeine-containing products (coffee, tea, energy drinks)"},{"src":["epmc_yerba_safety"],"note":"the 2026 narrative review lists concurrent medication use as one of the things mate safety depends on; no specific drug pair was identified in the fetched sources","with":"medicines in general"}],"sources":[{"id":"ods_caffeine_sources","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), caffeine section, herbal caffeine sources (read via the archive.org capture; ods.od.nih.gov returns 403 to a direct fetch)","quote":"Many dietary supplements promoted for weight loss contain added caffeine or an herbal source—such as guarana (Paullinia cupana), kola (or cola) nut (Cola nitida), and yerba maté (Ilex paraguariensis)—that naturally contains caffeine","accessed":"2026-08-27"},{"id":"ods_caffeine_safety","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), caffeine safety, intake benchmarks (read via the archive.org capture; ods.od.nih.gov returns 403 to a direct fetch)","quote":"For healthy adults, FDA and the European Food Safety Authority (EFSA) state that up to 400 mg/day caffeine does not pose safety concerns … the American Medical Association recommends that adolescents consume no more than 100 mg/day","accessed":"2026-08-27"},{"id":"ods_combo_trial","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), caffeine section, 45-day yerba maté / guarana / damiana trial (read via the archive.org capture; ods.od.nih.gov returns 403 to a direct fetch)","quote":"47 adults who were overweight (BMI 26–30) were randomized to take a combination product containing 336 mg yerba maté (1%–1.5% caffeine), 285 mg guarana (3%–6% caffeine), and 108 mg damiana … or placebo … for 45 days","accessed":"2026-08-27"},{"id":"ods_combo_result","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), caffeine section, result of the 45-day combination trial (read via the archive.org capture; ods.od.nih.gov returns 403 to a direct fetch)","quote":"participants taking the herbal product lost a mean of 5.1 kg compared to 0.3 kg for those taking the placebo","accessed":"2026-08-27"},{"id":"epmc_yerba_composition","url":"https://europepmc.org/article/MED/42588157","label":"Ilex paraguariensis (Yerba Mate): A Narrative Review of Bioactive Compounds, Biological Activities, and Green Extraction Technologies (Nutrients 2026) — background","quote":"Ilex paraguariensis (yerba mate) is a widely consumed botanical beverage rich in caffeoylquinic acids, methylxanthines, flavonoids, and saponins.","accessed":"2026-08-27"},{"id":"epmc_yerba_safety","url":"https://europepmc.org/article/MED/42588157","label":"Ilex paraguariensis (Yerba Mate): A Narrative Review (Nutrients 2026) — safety findings","quote":"Safety depends on total caffeine exposure, preparation temperature, processing-related contaminants, individual susceptibility, and concurrent medication use. Very-hot consumption and smoke-derived polycyclic aromatic hydrocarbons represent avoidable risks.","accessed":"2026-08-27"},{"id":"epmc_yerba_conclusion","url":"https://europepmc.org/article/MED/42588157","label":"Ilex paraguariensis (Yerba Mate): A Narrative Review (Nutrients 2026) — conclusion","quote":"yerba mate may represent a functional beverage and source of bioactive ingredients, but therapeutic claims remain unsupported","accessed":"2026-08-27"},{"id":"epmc_yerba_meta","url":"https://europepmc.org/article/MED/41244043","label":"Yerba Maté and its impact on glycemic control and metabolic health: a systematic review and meta-analysis (Frontiers in Endocrinology 2025; 13 RCTs)","quote":"No significant effects were found on triglycerides, total cholesterol, HDL-C, LDL-C, fasting glucose, fasting insulin, waist circumference, or BMI. Adverse events included mucosal irritation, insomnia, tachycardia, angina, headache, and gastrointestinal discomfort.","accessed":"2026-08-27"},{"id":"hsa_caffeine_annexb","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025) — Annex B, item 1 (caffeine); the quote joins the 'Concerns / Issues' and 'Risk Mitigation Measures' columns of that one row","quote":"Excessive use may cause nervousness, irritability, sleep disturbances, diuresis, increased blood pressure, heart rate and gastrointestinal disturbances … Indicate the amount of caffeine in your product so that consumers are aware of the amount consumed.","accessed":"2026-08-27"},{"id":"hsa_annex_notlisted","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (Oct 2025) — Annex A (118 substances, prohibited/restricted) and Annex B (4 substances: caffeine, Camellia sinensis extract, Hypericum perforatum, L-tryptophan) both read in full: yerba mate / Ilex paraguariensis is NOT LISTED in Annex A or Annex B","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/yerba-mate","label":"iHerb Singapore — Yerba Mate category (default order, \"1 - 11 of 11 results\")","quote":"Mate Factor, Organic Yerba Mate, Loose Herb Tea, Fresh Green … EcoTeas, Loose Yerba Mate, Green Energy, Unsmoked … Wisdom Of The Ancients, Yerba Mate Royale® … Choice Organics, Herbal Yerba Mate, Apple Mate … The Tao of Tea, Organic Yerba Mate","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:34.039038+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}