{"ok":true,"entry":{"slug":"vanadium","kind":"supplement","name":"vanadium","aliases":["vanadyl sulfate"],"brands_sg":["Source Naturals","Natural Factors","Swanson Vitamins","Nutricost","Life Extension"],"class":"trace mineral","tags":["general","fitness"],"use_for":"no proven use — insulin-like claims have not held up","use_after":null,"use_duration":null,"take_with":null,"pros":[],"cons":["review: no rigorous evidence for glucose control","issn lists vanadyl sulfate under little-to-no evidence","gastrointestinal side effects were common in trials"],"dose_note":"the trials reviewed used 30–150 mg of oral vanadium a day; the adult upper limit is 1.8 mg a day","dosage":{"ul":1.8,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"established","population":"general adult","hsa_max_daily":null},"ul_status":"established","sg_class":null,"cautions":["over 1.8 mg a day — above the adult upper limit","on diabetes medicines — ask your doctor before adding vanadium","the dri table says vanadium supplements should be used with caution","not named in hsa's annexes — that list is not exhaustive"],"clashes":[],"sources":[{"id":"qjm_smith2008","url":"https://europepmc.org/article/MED/18319296","label":"Smith, Pickering & Lewith — A systematic review of vanadium oral supplements for glycaemic control in type 2 diabetes mellitus (QJM 2008;101:351-8)","quote":"There is no rigorous evidence that oral vanadium supplementation improves glycaemic control in type 2 diabetes. The routine use of vanadium for this purpose cannot be recommended.","accessed":"2026-08-27"},{"id":"qjm_smith2008_detail","url":"https://europepmc.org/article/MED/18319296","label":"Smith et al. 2008 (QJM) — results, doses studied and tolerability","quote":"One hundred and fifty one studies were found but none met the inclusion criteria … clinical trials of 30-150 mg daily oral vanadium supplementation in diabetic humans. Only five were identified … Treatment with vanadium often results in gastrointestinal side-effects.","accessed":"2026-08-27"},{"id":"issn_kerksick2018_minerals","url":"https://europepmc.org/article/PMC/PMC6090881","label":"Kerksick et al. — ISSN exercise & sports nutrition review update: research & recommendations (JISSN 2018), minerals summary","quote":"there is little evidence that boron, chromium, magnesium, or vanadium affect exercise capacity or training adaptations in healthy individuals eating a normal diet","accessed":"2026-08-27"},{"id":"issn_kerksick2018_vanadyl","url":"https://europepmc.org/article/PMC/PMC6090881","label":"Kerksick et al. 2018 (JISSN) — vanadyl sulfate section","quote":"no studies are available that support the ability of vanadyl sulfate supplementation to impact strength or muscle mass in non-diabetic individuals who are currently resistance training","accessed":"2026-08-27"},{"id":"issn_kerksick2018_table3","url":"https://europepmc.org/article/PMC/PMC6090881","label":"Kerksick et al. 2018 (JISSN) — Table 3, categorisation of muscle-building supplements","quote":"III. Little to No Evidence to Support Efficacy and/or Safety … • Tribulus terrestris • Vanadyl sulfate • Zinc-magnesium aspartate","accessed":"2026-08-27"},{"id":"jissn_williams2005","url":"https://europepmc.org/article/PMC/PMC2129162","label":"Williams — Dietary Supplements and Sports Performance: Minerals (JISSN 2005;2:43-9)","quote":"the limited data available do not support an anabolic effect of vanadium in young healthy individuals","accessed":"2026-08-27"},{"id":"dri_ul_2019","url":"https://www.ncbi.nlm.nih.gov/books/NBK545442/table/appJ_tab9/","label":"NASEM Food and Nutrition Board — Dietary Reference Intakes: Tolerable Upper Intake Levels, Elements (reprinted in Dietary Reference Intakes for Sodium and Potassium, 2019, Appendix J)","quote":"Vanadium (mg/d) … 19–30 y 1.8 … 31–50 y 1.8 … 51–70 y 1.8 … > 70 y 1.8","accessed":"2026-08-27"},{"id":"dri_ul_2019_footnote","url":"https://www.ncbi.nlm.nih.gov/books/NBK545442/table/appJ_tab9/","label":"NASEM — DRI Tolerable Upper Intake Levels, Elements, footnote d (vanadium)","quote":"there is no justification for adding vanadium to food and vanadium supplements should be used with caution. The UL is based on adverse effects in laboratory animals","accessed":"2026-08-27"},{"id":"hsa_annex_scope","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA Singapore — Prohibited and Restricted Ingredients in HS and TM, GL-CHPB-1-012 Rev. 001 (Oct 2025), clauses 3.1–3.2; vanadium appears in neither Annex A nor Annex B, and is absent from Table 5 of the Health Supplements Guidelines","quote":"A list of these substances which TM and HS should not contain except subject to such restrictions and conditions to ensure safety in Singapore is provided in Annex A. This list is not exhaustive.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/vanadium","label":"iHerb Singapore — Vanadium category page, default “Featured” order, 9 results (brands from positions 1–8)","quote":"Source Naturals, Vanadium with Chromium, 90 Tablets … Natural Factors, Chromium & Vanadium … Source Naturals, Vanadyl Sulfate, 10 mg … Swanson Vitamins, Albion Vanadium & Chromium … Nutricost, Vanadium … Life Extension, Vanadyl Sulfate","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:34.039038+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}