{"ok":true,"entry":{"slug":"sodium-bicarbonate","kind":"medication","name":"sodium bicarbonate","aliases":["baking soda","NaHCO3"],"brands_sg":["Gaviscon","Ural","Inon","Ohta's Isan","Gascovid"],"class":"antacid / alkalinising agent","tags":["digestive"],"use_for":"acid indigestion, heartburn · urine alkalinising in sg","use_after":"after meals and at bedtime per the sg gaviscon label","use_duration":null,"take_with":"water · tablets swallowed whole or dissolved (us label)","pros":["oral antacid forms are general sale list in sg","us otc label purpose: antacid for heartburn relief","sg also registers it as a urinary alkaliniser (ural)"],"cons":["sodium load — 20 ml gaviscon = 11.06 mmol sodium","us label: maximum dosage not beyond 2 weeks","the sg 500 mg capsule is prescription-only"],"dose_note":"the us otc label for sodium bicarbonate 650 mg tablets (purpose: \"Antacid\") states \"adults 60 years of age and over: 1-2 tablets every 4 hours, not more than 12 tablets in 24 hours\" and \"adults under 60 years of age: 1-4 tablets every 4 hours, not more than 24 tablets in 24 hours\", with \"do not use the maximum dosage for more than 2 weeks\". the singapore gaviscon double action liquid insert (SIN14016P), a calcium carbonate + sodium alginate + sodium bicarbonate combination, caps itself at \"Adults and children over 12 years: Take 10–20ml (Two to four 5ml spoonfuls) after meals and at bedtime, up to four times a day\". as directed on the label or by your pharmacist/doctor.","dosage":null,"ul_status":null,"sg_class":"general-sale","cautions":["sodium-restricted diet — both labels: ask a doctor first","on prescription medicines — antacids can interact","symptoms lasting more than 2 weeks — us label: see a doctor","under 12 years — sg gaviscon label: only if a doctor says so"],"clashes":[{"src":["hh_levo_avoid"],"note":"sg leaflet: indigestion remedies 2 h before or after — absorption drops","with":"levofloxacin and other fluoroquinolones"},{"src":["fda_cefu_int"],"note":"us label: at least 1 hour before or 2 hours after short-acting antacids","with":"cefuroxime axetil"},{"src":["fda_nahco3_warn"],"note":"us otc label: antacids may interact with certain prescription drugs","with":"prescription medicines in general"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset; filtered locally for sodium bicarbonate / sodium hydrogen carbonate)","quote":"31 rows: Forensicclassification 'General Sale List' 24, 'Prescription Only' 6, 'Pharmacy Only' 1. Of the 15 oral rows, 13 are General Sale List — e.g. SIN09494P GAVISCON LIQUID; SIN14374P Ural Effervescent Granules; SIN03440P INON GRANULES","accessed":"2026-08-27"},{"id":"ndf_gaviscon_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14016p/","label":"MOH National Drug Formulary — GAVISCON DOUBLE ACTION LIQUID, SUSPENSION [SIN14016P], product information","quote":"CALCIUM CARBONATE - 325 MG/10 ML SODIUM ALGINATE - 500 MG/10 ML SODIUM BICARBONATE - 213 MG/10 ML … Forensic Classification GENERAL SALE LIST","accessed":"2026-08-27"},{"id":"ndf_gaviscon_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14016p/","label":"MOH National Drug Formulary — GAVISCON DOUBLE ACTION [SIN14016P], indication","quote":"brings relief from the pain and discomfort of heartburn and acid indigestion … neutralising excess stomach acid to relieve pain and discomfort … forming a protective barrier over the stomach contents","accessed":"2026-08-27"},{"id":"ndf_gaviscon_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14016p/","label":"MOH National Drug Formulary — GAVISCON DOUBLE ACTION [SIN14016P], dosage","quote":"Adults and children over 12 years: Take 10–20ml (Two to four 5ml spoonfuls) after meals and at bedtime, up to four times a day. Children under 12 years: Not to be given unless recommended by your doctor.","accessed":"2026-08-27"},{"id":"ndf_gaviscon_sodium","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14016p/","label":"MOH National Drug Formulary — GAVISCON DOUBLE ACTION [SIN14016P], before taking this product","quote":"Each 20ml dose contains 11.06 mmol sodium and 6.5 mmol calcium. If you have been advised a diet restricted in any of these please ask your doctor before taking this product.","accessed":"2026-08-27"},{"id":"ndf_nahco3cap_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin05414p/","label":"MOH National Drug Formulary — SODIUM BICARBONATE CAPSULE 500 MG [SIN05414P], product information","quote":"SODIUM BICARBONATE - 500 MG … Dosage Form CAPSULE … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code B05CB04","accessed":"2026-08-27"},{"id":"ndf_ural_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14374p/","label":"MOH National Drug Formulary — URAL EFFERVESCENT GRANULES [SIN14374P], product information","quote":"CITRIC ACID ANHYDROUS - 0.72 G SODIUM BICARBONATE - 1.76 G SODIUM CITRATE ANHYDROUS - 0.63 G TARTARIC ACID - 0.89 G … GENERAL SALE LIST … ATC code G04BX","accessed":"2026-08-27"},{"id":"fda_nahco3_purpose","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a0cc46d-372e-4175-932a-065e82d8d353","label":"FDA DailyMed — Sodium Bicarbonate 10 gr. (650 mg) tablets (Gendose Pharmaceuticals), OTC label eff. 2026-04-13","quote":"Purpose Antacid … Uses relieves acid indigestion heartburn sour stomach upset stomach associated with these symptoms","accessed":"2026-08-27"},{"id":"fda_nahco3_dose","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a0cc46d-372e-4175-932a-065e82d8d353","label":"FDA DailyMed — Sodium Bicarbonate 650 mg tablets, Directions","quote":"do not use the maximum dosage for more than 2 weeks tablets may be swallowed whole or dissolved in water … adults under 60 years of age: 1-4 tablets every 4 hours, not more than 24 tablets in 24 hours","accessed":"2026-08-27"},{"id":"fda_nahco3_warn","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a0cc46d-372e-4175-932a-065e82d8d353","label":"FDA DailyMed — Sodium Bicarbonate 650 mg tablets, Warnings","quote":"Ask a doctor before use if you have a sodium restricted diet … Antacids may interact with certain prescription drugs. Stop use and ask a doctor if symptoms last more than 2 weeks","accessed":"2026-08-27"},{"id":"hh_levo_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/levofloxacin","label":"HealthHub (National Medication Information workgroup) — Levofloxacin: what food or medication should I avoid, reviewed 31 May 2024","quote":"Indigestion remedies (e.g. Antacids) … You should take the above products 2 hours before or after Levofloxacin as taking them together reduces the absorption of Levofloxacin into your body.","accessed":"2026-08-27"},{"id":"fda_cefu_int","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=119c4d09-2324-498f-9318-1f8db49ad4b6","label":"FDA DailyMed — Cefuroxime axetil tablets (A-S Medication Solutions), Drug Interactions, eff. 2025-10-08","quote":"Administer cefuroxime axetil at least 1 hour before or 2 hours after administration of short-acting antacids. Histamine-2 (H2) antagonists and proton pump inhibitors should be avoided.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:31.341231+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}