{"ok":true,"entry":{"slug":"slippery-elm","kind":"supplement","name":"slippery elm","aliases":["Ulmus rubra"],"brands_sg":["NOW Foods","Nature's Way","Micro Ingredients","Solaray","J&R Port Trading"],"class":"botanical","tags":["gut"],"use_for":"a traditional demulcent for throat and gut irritation","use_after":null,"use_duration":null,"take_with":"water · the inner-bark mucilage swells into a gel","pros":["livertox: generally recognized as safe (gras)","no published case reports of liver injury","mucilage forms a physical layer over mucosa"],"cons":["trials of slippery elm on its own are lacking","the one gut trial used a 7-herb mix, no placebo","rare cutaneous allergic symptoms reported"],"dose_note":"no single-ingredient dose can be quoted from the sources read: livertox says there is no reliable data on adverse events and that no large-scale clinical trials have reported on them, and the 2022 nutrients review says trials examining slippery elm's singular effect are lacking; the one upper-gi trial gave a seven-ingredient formula (curcumin, aloe vera, slippery elm, guar gum, pectin, peppermint oil and glutamine) at 5 g a day for 4 weeks then 10 g a day, single-arm with no placebo, so none of that gram figure belongs to slippery elm alone; no rda, ul, fda daily value or hsa singapore daily limit exists for it","dosage":{"ul":null,"unit":null,"fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["rare cutaneous allergic symptoms have been linked to slippery elm (livertox)","no large-scale clinical trials have reported on its adverse events (livertox)","not listed in hsa's prohibited or restricted annexes — that is not a safety finding"],"clashes":[],"sources":[{"id":"livertox_slippery_elm","url":"https://www.ncbi.nlm.nih.gov/books/NBK599741/","label":"NIH LiverTox (NIDDK) — Slippery Elm monograph, Bookshelf NBK599741, references updated 5 January 2024","quote":"the inner bark … used orally to treat sore throat and gastrointestinal upset … called slippery because of the slippery texture of the inner bark when it is chewed or mixed with water","accessed":"2026-08-27"},{"id":"livertox_slippery_elm_ae","url":"https://www.ncbi.nlm.nih.gov/books/NBK599741/","label":"NIH LiverTox — Slippery Elm, Background (adverse-event data and GRAS status)","quote":"There is no reliable data on adverse events from slippery elm and it is designated as 'generally recognized as safe' (GRAS). There have been no large scale clinical trials that have reported on adverse events","accessed":"2026-08-27"},{"id":"livertox_slippery_elm_allergy","url":"https://www.ncbi.nlm.nih.gov/books/NBK599741/","label":"NIH LiverTox — Slippery Elm, Background (allergic reactions)","quote":"Slippery elm has been linked to rare instances cutaneous allergic symptoms.","accessed":"2026-08-27"},{"id":"livertox_slippery_elm_liver","url":"https://www.ncbi.nlm.nih.gov/books/NBK599741/","label":"NIH LiverTox — Slippery Elm, Hepatotoxicity and likelihood score","quote":"despite common use, there have been no published case reports of liver injury attributed to slippery elm … Likelihood score: E (unlikely cause of clinically apparent liver injury)","accessed":"2026-08-27"},{"id":"komolafe2025_slippery_elm","url":"https://europepmc.org/article/PMC/PMC11944625","label":"Natural Products in the Management of Gastroesophageal Reflux Disease (Komolafe et al., Nutrients 2025) — section 5.6 and limitations","quote":"The mucilage content of Ulmus rubra (slippery elm) absorbs water and forms a viscous gel that constitutes a protective barrier over mucosal surfaces … research on botanicals including marshmallow root, slippery elm … is limited","accessed":"2026-08-27"},{"id":"schulz2022_slippery_elm","url":"https://europepmc.org/article/PMC/PMC8839470","label":"Effectiveness of Nutritional Ingredients on Upper Gastrointestinal Conditions and Symptoms: A Narrative Review (Schulz, Ahuja & Slavin, Nutrients 2022)","quote":"Slippery elm has received increased interest, but trials examining its singular effect are lacking","accessed":"2026-08-27"},{"id":"schulz2022_ried_trial","url":"https://europepmc.org/article/PMC/PMC8839470","label":"Schulz et al., Nutrients 2022 — appraisal of the Ried 2020 multi-herb formula trial","quote":"The authors reported two mild AEs related to the trial (severe bloating and constipation) which resulted in dropout … the intervention period was a single-arm design and lacked a placebo","accessed":"2026-08-27"},{"id":"schulz2022_ried_dose","url":"https://europepmc.org/article/PMC/PMC8839470","label":"Schulz et al., Nutrients 2022 — Table 6, Ried 2020 intervention detail","quote":"IG: 5 g, 1×/day formula mixed with water for 4 weeks, followed by 10 g/d for the second month … (Curcumin, Aloe vera, slippery elm, guar gum, pectin, peppermint oil, and glutamine)","accessed":"2026-08-27"},{"id":"hsa_prohibited","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (October 2025), Annex A (118 rows) and Annex B (4 rows) — slippery elm / Ulmus rubra not listed in either (alphabetical neighbours 103. Symphytum asperum, 104. Urginea maritima)","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"hsa_hs_guidelines","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. No. 020 (January 2026), clause 4.8 with Tables 4–5 (vitamins and minerals only — no botanical rows)","quote":"4.8 HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/slippery-elm","label":"iHerb Singapore — Slippery Elm category page, default listing order","quote":"1 - 25 of 25 results: NOW Foods, Slippery Elm; Nature's Way, Slippery Elm Bark; Micro Ingredients, Organic Slippery Elm Bark; Solaray, True Herbs, Slippery Elm; J&R Port Trading, Organic Slippery Elm Bark","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:31.341231+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}