{"ok":true,"entry":{"slug":"silica","kind":"supplement","name":"silica","aliases":["silicon","orthosilicic acid","BioSil"],"brands_sg":["Eidon Ionic Minerals","Biosil","Silicium Laboratories","NOW Foods","Futurebiotics"],"class":"mineral","tags":["skin-hair","bone-joint"],"use_for":"hsa allows a normal-hair claim · bone data is observational","use_after":"daily","use_duration":null,"take_with":"orthosilicic acid is the highly bioavailable form","pros":["hsa lists silicon for a normal-hair claim","up to 50 mg/day of osa: no adverse effects seen","orthosilicic acid absorbs well from food and water"],"cons":["human evidence is limited and mostly observational","review says data cannot justify supplementation","no upper limit set — that is not the same as safe"],"dose_note":"dietary silicon runs roughly 15–60 mg a day depending on region; human trials of orthosilicic acid supplements at doses up to 50 mg a day report no adverse effects, and the review still concludes the data cannot support a recommended intake","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["kidney problems — the kidneys are what clear excess osa","inhaled crystalline silica is a different, toxic thing","nano-silica and formulated silicon products — not covered"],"clashes":[],"sources":[{"id":"melenikioti2026","url":"https://europepmc.org/article/PMC/PMC12899721","label":"Dietary Lithium, Silicon, and Boron: An Updated Critical Review (Melenikioti et al., Nutrients 2026) — silicon summary table","quote":"Silicon (Si) Bone Health, Collagen Synthesis, Vascular and Epithelial Integrity … Moderate: Strongest findings in observational studies on Bone Mineral Density (BMD). Supported by biomarker-oriented interventions","accessed":"2026-08-27"},{"id":"melenikioti2026_ul","url":"https://europepmc.org/article/PMC/PMC12899721","label":"Melenikioti et al., Nutrients 2026 — silicon safety and upper limit","quote":"Regulatory bodies such as the European Food Safety Authority (EFSA) and the WHO have not established an official Upper Limit (UL) for dietary OSA, largely because the excess soluble OSA is rapidly and efficiently excreted by the kidneys","accessed":"2026-08-27"},{"id":"melenikioti2026_dose","url":"https://europepmc.org/article/PMC/PMC12899721","label":"Melenikioti et al., Nutrients 2026 — supplemental OSA doses studied","quote":"human clinical trials demonstrate that consuming OSA through supplements (not supplemental nano-silica or formulated silicon products; those products require further investigation) at doses up to 50 mg/day … shows no adverse effects","accessed":"2026-08-27"},{"id":"melenikioti2026_silica","url":"https://europepmc.org/article/PMC/PMC12899721","label":"Melenikioti et al., Nutrients 2026 — dietary OSA vs industrial crystalline silica","quote":"it is imperative to distinguish this naturally occurring dietary OSA from industrial crystalline silica, which is a particulate respiratory toxin associated with occupational hazards like silicosis and bears no relationship to human nutrition","accessed":"2026-08-27"},{"id":"melenikioti2026_conclusion","url":"https://europepmc.org/article/PMC/PMC12899721","label":"Melenikioti et al., Nutrients 2026 — abstract conclusions","quote":"Human evidence remains limited … Si by bone-related observational studies and biomarker-oriented interventions … current human data are insufficient to justify dietary recommendations or supplementation","accessed":"2026-08-27"},{"id":"melenikioti2026_intake","url":"https://europepmc.org/article/PMC/PMC12899721","label":"Melenikioti et al., Nutrients 2026 — Table 1, estimated dietary silicon intake by region","quote":"Silicon Intake (mg/day) … Northern Europe 10–150 20–50 1–3 Mineral waters, grains, vegetables Orthosilicic acid highly bioavailable … Southern Europe 5-80 30-60 1–4 Mineral waters, wine, fruits … Asia 10–300 15–40 1–3 Rice, vegetables","accessed":"2026-08-27"},{"id":"hsa_hs_2026_claims","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Health Supplements Guidelines (Jan 2026), List of Health Claims attributable to vitamins and/or minerals","quote":"List of Health Claims that are attributable to vitamin(s) and/or mineral(s) … Contribute to maintenance of normal hair • Selenium, silicon, zinc … mucous membranes • Selenium, silicon","accessed":"2026-08-27"},{"id":"hsa_prohibited_2025","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev 001 (Oct 2025)","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list [silica / silicon / horsetail (Equisetum) not listed in Annex A or B]","accessed":"2026-08-27"},{"id":"hsa_hs_2026","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Health Supplements Guidelines, GL-CHPB-3-001 Rev 020 (Jan 2026), Table 5: Minerals Limits","quote":"Table 5: Minerals Limits … Nutrient Maximum Daily Limit Boron 6.4 mg Calcium 1200 mg Chromium 0.5 mg Copper 2 mg Iodine 0.15 mg Iron 15 mg* Magnesium 350 mg Manganese 3.5 mg … Selenium 0.2 mg Zinc 15 mg","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/silica","label":"iHerb Singapore — Silica category page, Supplements › Minerals (default order, 30 results)","quote":"Eidon Ionic Minerals, Silica, Liquid Concentrate … Biosil, Advanced Collagen Generator®, 120 Original Capsules … Silicium Laboratories, Orgono® Living Silica®, Collagen Booster, 22.5 mg … NOW Foods, Silica Complex with Horsetail Extract, 180 Tablets … Futurebiotics, Super Silica Complex™","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:31.341231+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}