{"ok":true,"entry":{"slug":"risperidone","kind":"medication","name":"risperidone","aliases":["Risperdal"],"brands_sg":["Risperdal","Risperidex","Apo-Risperidone","Risperidone Mevon","Risperdal Consta"],"class":"atypical antipsychotic","tags":["mental-health"],"use_for":"nhs: schizophrenia and the mania of bipolar disorder","use_after":"nhs: once or twice a day · days to months to work fully","use_duration":null,"take_with":"healthhub: with or without food · liquid not mixed with tea","pros":["healthhub: tablets, oral solution and a depot injection","nhs: it can help the symptoms, though it does not cure","healthhub: sg leaflet pairs each side effect with tips"],"cons":["healthhub: sleepiness, weight gain, movement effects","healthhub: raised prolactin — period and breast changes","healthhub: rare tardive dyskinesia and seizures"],"dose_note":"no singapore package insert was read. the us label for risperidone tablets states, for adults with schizophrenia, \"Efficacy has been demonstrated in a range of 4 mg to 16 mg per day\" and \"The safety of doses above 16 mg per day has not been evaluated in clinical trials\" — 16 mg a day is the top of the labelled range, and the same label notes doses above 6 mg a day on twice-daily dosing were not more effective and are generally not recommended. nhs says most people feel better on 4 mg to 6 mg a day. singapore registers 1 mg and 2 mg tablets, a 1 mg/ml solution and 25/37.5/50 mg depot injections. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["healthhub: diabetes — blood sugar control can worsen","healthhub: kidney or liver disease, or breast cancer","healthhub: heart problems, irregular heartbeat or stroke","healthhub: dementia, parkinson's disease or seizures"],"clashes":[{"src":["nhs_ris_mix"],"note":"nhs lists these epilepsy medicines among those that may affect how risperidone works","with":"carbamazepine or phenytoin"},{"src":["nhs_ris_mix"],"note":"nhs lists these among medicines that may affect how risperidone works","with":"rifampicin or itraconazole"},{"src":["nhs_ris_mix"],"note":"nhs: risperidone can increase these sedating effects","with":"sedating medicines (diazepam, morphine, tramadol, chlorphenamine)"},{"src":["nhs_ris_mix"],"note":"nhs: st john's wort may stop it working as well; ginkgo can increase side effects","with":"st john's wort and ginkgo biloba"},{"src":["hh_ris_avoid"],"food":true,"note":"healthhub: it can cause excessive sleepiness","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 16 risperidone rows, 27 Aug 2026","quote":"RISPERDAL TABLET 1 mg SIN08061P and 2 mg SIN08058P · RISPERDAL ORAL SOLUTION 1 mg/ml SIN09905P · RISPERDAL CONSTA 25/37.5 mg/vial · RISPERIDEX SIN14418P · Apo-Risperidone — ATC N05AX08; all 16 rows read \"Prescription Only\"","accessed":"2026-08-27"},{"id":"nhs_ris_about","url":"https://www.nhs.uk/medicines/risperidone/about-risperidone/","label":"NHS medicines A–Z — Risperidone: about risperidone","quote":"It's an antipsychotic medicine that works by affecting chemicals in your brain, such as dopamine and serotonin. It does not cure your condition, but it can help the symptoms. Risperidone is only available on prescription.","accessed":"2026-08-27"},{"id":"nhs_ris_howto","url":"https://www.nhs.uk/medicines/risperidone/how-and-when-to-take-risperidone/","label":"NHS medicines A–Z — Risperidone: dosage and how to take risperidone","quote":"Most people feel better with daily doses of 4mg to 6mg. You can take it as a single dose each day or … half your dose in the morning and half in the evening.","accessed":"2026-08-27"},{"id":"nhs_ris_mix","url":"https://www.nhs.uk/medicines/risperidone/taking-risperidone-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Risperidone: taking risperidone with other medicines and herbal supplements","quote":"rifampicin …; carbamazepine or phenytoin …; itraconazole …; medicines that make you feel sleepy such as diazepam …, morphine or tramadol … While you're taking risperidone, do not take: St John's wort …; ginkgo biloba","accessed":"2026-08-27"},{"id":"hh_ris_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/risperidone","label":"HealthHub (Pharmaceutical Society of Singapore / MOH) — Risperidone: what is this medication for (leaflet reviewed 25 May 2026)","quote":"Risperidone belongs to a class of medications known as atypical (second-generation) antipsychotic. It is used to treat and prevent the return of symptoms in Schizophrenia and other mental health related conditions","accessed":"2026-08-27"},{"id":"hh_ris_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/risperidone","label":"HealthHub — Risperidone: how should I take or use this medication","quote":"Risperidone may be taken with or without food … You may mix the dose of oral solution with a small glass of water, coffee, orange juice or low-fat milk. Do not mix with tea, cola or alcoholic drinks.","accessed":"2026-08-27"},{"id":"hh_ris_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/risperidone","label":"HealthHub — Risperidone: what are some common side effects of this medication","quote":"Difficulty sleeping … Drowsiness or feeling tired … Increase in appetite, weight gain … Increased prolactin hormone in the body (hyperprolactinemia): This may result in changes in menstrual cycle in females … Muscle movement side effects","accessed":"2026-08-27"},{"id":"hh_ris_rare","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/risperidone","label":"HealthHub — Risperidone: rare but serious side effects","quote":"Rarely this medication may cause: Seizures (fits); … neuroleptic malignant syndrome; Uncontrollable movements (such as in the face, tongue, jaw or other parts of the body) (tardive dyskinesia); … signs and symptoms of stroke","accessed":"2026-08-27"},{"id":"hh_ris_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/risperidone","label":"HealthHub — Risperidone: what precautions should I take","quote":"You have diabetes. Risperidone may sometimes worsen blood sugar control … Kidney or liver disease, breast cancer, irregular heartbeat or other heart problems, stroke … dementia, Parkinson's disease","accessed":"2026-08-27"},{"id":"hh_ris_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/risperidone","label":"HealthHub — Risperidone: what food or medication should I avoid","quote":"Avoid drinking alcohol while taking Risperidone as it can cause excessive sleepiness.","accessed":"2026-08-27"},{"id":"fda_ris_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22risperidone%22&limit=5","label":"US label for risperidone tablets (Westminster Pharmaceuticals, effective 2025-12-07) via openFDA drug/label.json, Dosage and Administration","quote":"demonstrated in a range of 4 mg to 16 mg per day … doses above 6 mg per day … are generally not recommended … The safety of doses above 16 mg per day has not been evaluated","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}