{"ok":true,"entry":{"slug":"ramipril","kind":"medication","name":"ramipril","aliases":["Tritace"],"brands_sg":["Tritace","Trinomia"],"class":"ACE inhibitor","tags":["heart-bp"],"use_for":"nhs: high blood pressure, heart failure, after heart attack","use_after":"nhs: first dose at bedtime — it can make you feel dizzy","use_duration":null,"take_with":"healthhub: with or without food · nhs: swallowed whole","pros":["nhs: helps prevent future strokes and heart attacks","nhs: usually once or twice a day, often for years","sg register: tritace 2.5 mg and 5 mg tablets registered"],"cons":["healthhub: a dry, annoying cough that does not go away","nhs: alcohol adds to the dizziness and lightheadedness","nhs: blood tests before starting and on dose changes"],"dose_note":"no singapore package insert was read. the nhs page states \"The maximum dose is 5mg twice a day or 10mg once a day\" for ramipril in the uk. the us label for ramipril capsules is wider: \"The usual maintenance dosage range is 2.5 mg to 20 mg per day administered as a single dose or in two equally divided doses\", with an explicit maximum of 5 mg a day only in renal impairment. the two label maxima disagree — 10 mg/day (uk) against a 20 mg/day range top (us). singapore registers 2.5 mg and 5 mg tablets. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["pregnancy — healthhub: stop as soon as pregnancy is known","healthhub: potassium and kidney function may be monitored","vomiting, diarrhoea or fever — nhs: tell the doctor","healthhub: allergy to ramipril or any ingredient"],"clashes":[{"src":["nhs_ram_mix"],"note":"nhs lists these; it adds that daily low-dose 75mg aspirin is safe with ramipril","with":"nsaids such as ibuprofen or indometacin"},{"src":["nhs_ram_mix"],"note":"nhs lists these among medicines that affect potassium levels","with":"potassium-raising medicines (spironolactone, amiloride, potassium)"},{"src":["nhs_ram_mix"],"note":"nhs lists medicines that make you pee more among those to tell the doctor about","with":"diuretics such as furosemide"},{"src":["nhs_ram_mix"],"note":"nhs lists it among medicines to tell the doctor about","with":"lithium"},{"src":["nhs_ram_mix"],"note":"nhs lists immune-calming medicines among those to tell the doctor about","with":"ciclosporin or tacrolimus"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 5 ramipril rows, 27 Aug 2026","quote":"TRITACE 2.5 TABLET 2.5 mg SIN09591P · TRITACE 5 TABLET 5 mg SIN09592P (ATC C09AA05) · TRINOMIA HARD CAPSULES 100mg/20mg/2.5mg, /5mg, /10mg (ATC C10BX06); all 5 rows read Forensicclassification \"Prescription Only\"","accessed":"2026-08-27"},{"id":"nhs_ram_about","url":"https://www.nhs.uk/medicines/ramipril/about-ramipril/","label":"NHS medicines A–Z — Ramipril (Tritace): about ramipril","quote":"Ramipril helps prevent future strokes, heart attacks and kidney problems … Your very first dose of ramipril may make you feel dizzy, so it's best to take it at bedtime … Drinking alcohol can make you feel dizzy or lightheaded.","accessed":"2026-08-27"},{"id":"nhs_ram_howto","url":"https://www.nhs.uk/medicines/ramipril/how-and-when-to-take-ramipril/","label":"NHS medicines A–Z — Ramipril: dosage and how to take ramipril","quote":"The maximum dose is 5mg twice a day or 10mg once a day. … You can take ramipril with or without food. Swallow ramipril tablets or capsules whole with a drink of water.","accessed":"2026-08-27"},{"id":"nhs_ram_mix","url":"https://www.nhs.uk/medicines/ramipril/taking-ramipril-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Ramipril: taking ramipril with other medicines and herbal supplements","quote":"NSAIDs … such as ibuprofen, indometacin or aspirin (daily low-dose aspirin of 75mg is safe to take with ramipril); medicines that can increase the amount of potassium … such as spironolactone, triamterene, amiloride; ciclosporin or tacrolimus; lithium","accessed":"2026-08-27"},{"id":"hh_ram_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ramipril","label":"HealthHub (Pharmaceutical Society of Singapore / MOH) — Ramipril: what is this medication for (leaflet reviewed 13 April 2026)","quote":"Ramipril lowers blood pressure by reducing the production of a substance called Angiotensin II which causes the blood vessels to narrow … can also be used for patients who have protein in their urine and other heart conditions.","accessed":"2026-08-27"},{"id":"hh_ram_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ramipril","label":"HealthHub — Ramipril: how should I take or use this medication","quote":"Do not stop taking your medicine without checking with your healthcare providers. This medicine may be taken with or without food","accessed":"2026-08-27"},{"id":"hh_ram_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ramipril","label":"HealthHub — Ramipril: what are some common side effects of this medication","quote":"The side effects include a dry, annoying cough that does not go away, dizziness and lightheadedness on getting up from a sitting or sleeping position. Very rarely, some patients might experience a loss of taste.","accessed":"2026-08-27"},{"id":"hh_ram_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ramipril","label":"HealthHub — Ramipril: what precautions should I take","quote":"Once you find out you are pregnant, stop the medication as soon as possible. Taking this medication may cause injury or death to your developing fetus … Your doctor may need to monitor your potassium levels and kidney function","accessed":"2026-08-27"},{"id":"fda_ram_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22ramipril%22&limit=5","label":"US label for ramipril capsules (Zydus Pharmaceuticals USA, effective 2026-06-05) via openFDA drug/label.json, Dosage and Administration","quote":"The usual maintenance dosage range is 2.5 mg to 20 mg per day administered as a single dose or in two equally divided doses. … a maximum total daily dose of 5 mg (renal impairment).","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}