{"ok":true,"entry":{"slug":"pumpkin-seed-oil","kind":"supplement","name":"pumpkin seed oil","aliases":["Cucurbita pepo seed oil"],"brands_sg":["NOW Foods","Swanson Vitamins","Micro Ingredients","Deva","Life Extension"],"class":"botanical oil","tags":["mens-health","skin-hair"],"use_for":"hair count in male-pattern hair loss · bph symptoms","use_after":null,"use_duration":"the hair trial ran 24 weeks; the bph trial 12 months","take_with":null,"pros":["hair count +40% vs +10% on placebo at 24 weeks","adverse effects no different from placebo (hair rct)","ipss fell by 3 months in the 12-month bph trial"],"cons":["hair rct: 76 men, one dose, one 24-week look","bph trial: 47 men split across four arms","prostate volume did not change in any arm"],"dose_note":"the hair trial gave 400 mg a day for 24 weeks; the bph trial gave 320 mg a day for 12 months, alone or with saw palmetto oil","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"adult men","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["both trials enrolled adult men only — 76 with hair loss, 47 with bph","extract source and processing differ between products","the combined pumpkin-plus-saw-palmetto arm did not beat either oil alone"],"clashes":[],"sources":[{"id":"pso_hair2014","url":"https://europepmc.org/article/PMC/PMC4017725","label":"Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial (Cho et al., Evid Based Complement Alternat Med 2014)","quote":"76 male patients with AGA received 400 mg of PSO per day or a placebo for 24 weeks","accessed":"2026-08-27"},{"id":"pso_hair2014_result","url":"https://europepmc.org/article/PMC/PMC4017725","label":"Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial (Cho et al., Evid Based Complement Alternat Med 2014)","quote":"Mean hair count increases of 40% were observed in PSO-treated men at 24 weeks, whereas increases of 10% were observed in placebo-treated men (P < 0.001). Adverse effects were not different in the two groups","accessed":"2026-08-27"},{"id":"pso_bph2009","url":"https://europepmc.org/article/PMC/PMC2809240","label":"Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia (Hong et al., Nutr Res Pract 2009)","quote":"a randomized, double-blind, placebo-controlled trial was performed over 12 months on 47 benign prostatic hyperplasia patients … Subjects received either sweet potato starch (group A, placebo, 320 mg/day), pumpkin seed oil (group B, 320 mg/day)","accessed":"2026-08-27"},{"id":"pso_bph2009_result","url":"https://europepmc.org/article/PMC/PMC2809240","label":"Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia (Hong et al., Nutr Res Pract 2009)","quote":"In groups B, C and D, the international prostate symptom score were reduced by 3 months … no difference was observed in prostate volume in all treatment groups … None of the parameters were significantly improved by combined treatment","accessed":"2026-08-27"},{"id":"pso_luts2025","url":"https://europepmc.org/article/MED/38411727","label":"Natural Products in the Treatment of Lower Urinary Tract Dysfunction and Infection (Lederer & Michel, Handb Exp Pharmacol 2025)","quote":"Most evidence for male LUTS is based on extracts from saw palmetto berries, stinging nettle roots, and pumpkin seeds … extracts from the same plants are likely to exhibit at least quantitative differences in potential active ingredients","accessed":"2026-08-27"},{"id":"hsa_prohibited_2025","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev 001 (Oct 2025)","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list [Cucurbita pepo / pumpkin seed oil not listed in Annex A or B]","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/pumpkin-seed-oil","label":"iHerb Singapore — Pumpkin Seed Oil category (default order)","quote":"NOW Foods, Pumpkin Seed Oil, 100 Softgels … Swanson Vitamins, Pumpkin Seed Oil, 1,000 mg … Micro Ingredients, Pumpkin Seed Oil, Cold Pressed … Deva, Vegan Pumpkin Seed Oil … Life Extension, Water-Soluble Pumpkin Seed Extract","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}