{"ok":true,"entry":{"slug":"pseudoephedrine","kind":"medication","name":"pseudoephedrine","aliases":["Sudafed","Clarinase","Zyrtec-D","Telfast D"],"brands_sg":["Zyrtec-D","Telfast D","Clarityn-D","Fedac","Panadol Cold Relief PSE"],"class":"decongestant","tags":["cold-flu","allergy"],"use_for":"blocked or stuffy nose from colds, sinusitis or allergies","use_after":"up to 4 times a day per nhs · not close to bedtime","use_duration":null,"take_with":"with or without food · with a drink of water (nhs)","pros":["healthhub: it is the part that clears a blocked nose","sg: pharmacy-only — no prescription needed (hsa)","otc label: relieves cold, hay fever, sinus congestion"],"cons":["restlessness, trouble sleeping, dry mouth (nhs)","nhs: a headache that persists — it can raise your bp","sg: sold only inside combination products (hsa)"],"dose_note":"us otc drug facts (30 mg tablets), adults and children 12 and over 2 tablets: 'take every 4-6 hours … do not take more than 4 doses in 24 hours'; nhs, 60 mg tablets: usual dose one tablet 'up to 4 times a day', and 'you can take pseudoephedrine for a few days, usually up to 5 to 7 days'; in singapore pseudoephedrine is registered only inside combination products whose own labels differ (fedac tablet: 1 tablet 3 times a day); as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["high blood pressure, heart disease or overactive thyroid — otc label says ask a doctor first","diabetes, glaucoma, prostate or bladder problems — otc label and healthhub say ask first","maois now or within 2 weeks of stopping — otc label says do not use","nervousness, dizziness or sleeplessness — otc label says stop and ask a doctor"],"clashes":[{"src":["fda_sudogest_warn","healthhub_pse_int","nhs_pse_int"],"note":"otc label: do not use with, or for 2 weeks after stopping, an maoi; healthhub and nhs say the same","with":"maois (e.g. moclobemide, selegiline)"},{"src":["nhs_pse_int2"],"note":"nhs: do not use at the same time as other medicines for a blocked nose, sprays included","with":"other decongestants (xylometazoline, oxymetazoline)"},{"src":["nhs_pse_int"],"note":"nhs: check with a pharmacist or doctor if you're taking these","with":"blood pressure medicines (beta blockers, methyldopa)"},{"src":["nhs_pse_int"],"note":"nhs: check with a pharmacist or doctor if you're taking amitriptyline, digoxin or ergotamine","with":"tricyclic antidepressants, digoxin, ergot alkaloids"},{"src":["healthhub_pse_int","hsa_register"],"note":"healthhub: check before taking two otc medicines together; sg packs already mix pseudoephedrine with other actives","with":"other otc cold or allergy combinations"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (open dataset on data.gov.sg, resource d_767279312753558cbf19d48344577084, pulled via datastore_search API; all 26 pseudoephedrine rows read, every one a combination product)","quote":"ZYRTEC-D · Pharmacy Only — TELFAST D TABLET · Pharmacy Only — CLARITYN-D 12HOUR REPETABS · Pharmacy Only — FEDAC TABLET · Pharmacy Only — PANADOL COLD RELIEF PSE CAPLET · Pharmacy Only — Aerius D-12 · Prescription Only","accessed":"2026-08-27"},{"id":"hsa_reclass","url":"https://www.hsa.gov.sg/therapeutic-products/registration-of-therapeutic-products/variation-application/reclassification/list-of-reclassified-medicines/","label":"HSA — List of reclassified medicines (forensic classification definitions: POM / P / GSL)","quote":"Pharmacy-Only Medicine (P): A therapeutic product that can be obtained from a pharmacist at a retail pharmacy without a prescription … generally indicated for the short-term treatment of a minor condition or symptoms that can be readily identified","accessed":"2026-08-27"},{"id":"healthhub_pse","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/loratadine-and-pseudoephedrine","label":"HealthHub (MOH Singapore) — Loratadine and Pseudoephedrine leaflet, pseudoephedrine text (article last reviewed 26 March 2026; no standalone pseudoephedrine page exists)","quote":"Pseudoephedrine helps to relieve blocked nose … You may take this medication with or without food … Trouble sleeping — Avoid taking too close to your sleep time … Restlessness … Dry mouth, skin and eyes … Headache","accessed":"2026-08-27"},{"id":"healthhub_pse_safe","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/loratadine-and-pseudoephedrine","label":"HealthHub (MOH Singapore) — Loratadine and Pseudoephedrine leaflet, precautions section (same page)","quote":"You have: High blood pressure … Heart disease or abnormal heart rhythm … Hyperthyroidism (overactive thyroid gland) … Diabetes … Glaucoma (high eye pressure) … Prostate or bladder problems … Liver or kidney problems","accessed":"2026-08-27"},{"id":"healthhub_pse_int","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/loratadine-and-pseudoephedrine","label":"HealthHub (MOH Singapore) — Loratadine and Pseudoephedrine leaflet, interactions section (same page)","quote":"Do not take this medication with, or within 14 days of stopping, monoamine oxidase inhibitors (e.g. moclobemide and selegiline) … always check with your healthcare professional before taking two over-the-counter medications at the same time","accessed":"2026-08-27"},{"id":"nhs_pse_how","url":"https://www.nhs.uk/medicines/pseudoephedrine/how-and-when-to-take-pseudoephedrine/","label":"NHS — How and when to take pseudoephedrine, 'Dosage and strength' (page last reviewed 2 November 2022)","quote":"Pseudoephedrine comes as 60mg tablets or as a liquid containing 30mg in 5ml. The usual dose is: adults and children aged 12 to 17 years – one 60mg tablet … up to 4 times a day","accessed":"2026-08-27"},{"id":"nhs_pse_how2","url":"https://www.nhs.uk/medicines/pseudoephedrine/how-and-when-to-take-pseudoephedrine/","label":"NHS — How and when to take pseudoephedrine, 'How to take it' and 'How long to take it for' (same page)","quote":"You can take pseudoephedrine tablets and liquid with or without food. Always take your tablets with a drink of water … You can take pseudoephedrine for a few days, usually up to 5 to 7 days","accessed":"2026-08-27"},{"id":"nhs_pse_se","url":"https://www.nhs.uk/medicines/pseudoephedrine/side-effects-of-pseudoephedrine/","label":"NHS — Side effects of pseudoephedrine (page last reviewed 2 November 2022)","quote":"A dry mouth … Feeling restless, nervous or shaky … Difficulty sleeping … If your headache does not go away, or gets worse, stop taking pseudoephedrine and contact 111. It may be because pseudoephedrine can increase your blood pressure","accessed":"2026-08-27"},{"id":"nhs_pse_int","url":"https://www.nhs.uk/medicines/pseudoephedrine/taking-pseudoephedrine-with-other-medicines-and-herbal-supplements/","label":"NHS — Taking pseudoephedrine with other medicines and herbal supplements (page last reviewed 2 November 2022)","quote":"Check with a pharmacist or doctor if you're taking: antidepressants known as monoamine oxidase inhibitors (MAOIs) … digoxin … tricyclic antidepressants, such as amitriptyline … ergot alkaloids … medicines for high blood pressure, such as beta blockers or methyldopa","accessed":"2026-08-27"},{"id":"nhs_pse_int2","url":"https://www.nhs.uk/medicines/pseudoephedrine/taking-pseudoephedrine-with-other-medicines-and-herbal-supplements/","label":"NHS — Taking pseudoephedrine with other medicines, decongestant warning (same page)","quote":"Do not use pseudoephedrine at the same time as other medicines for a blocked nose, such as xylometazoline and oxymetazoline. This includes nasal sprays or other tablets and capsules for congestion","accessed":"2026-08-27"},{"id":"fda_sudogest_use","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78faa497-6743-b85b-e053-2a91aa0ae822","label":"DailyMed / FDA — SUDOGEST (pseudoephedrine HCl 30 mg) tablet, OTC Drug Facts 'Uses' (Major Pharmaceuticals; label updated 12 May 2026)","quote":"temporarily relieves nasal congestion due to the common cold, hay fever or other upper respiratory allergies … temporarily relieves sinus congestion and pressure … Nasal decongestant","accessed":"2026-08-27"},{"id":"fda_sudogest_dose","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78faa497-6743-b85b-e053-2a91aa0ae822","label":"DailyMed / FDA — SUDOGEST, OTC Drug Facts 'Directions' (same label)","quote":"Pseudoephedrine HCl 30 mg … Directions: take every 4-6 hours … do not take more than 4 doses in 24 hours … adults & children 12 years & over 2 tablets","accessed":"2026-08-27"},{"id":"fda_sudogest_warn","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78faa497-6743-b85b-e053-2a91aa0ae822","label":"DailyMed / FDA — SUDOGEST, OTC Drug Facts 'Do not use' warning (same label)","quote":"Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) … or for 2 weeks after stopping the MAOI drug","accessed":"2026-08-27"},{"id":"fda_sudogest_ask","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=78faa497-6743-b85b-e053-2a91aa0ae822","label":"DailyMed / FDA — SUDOGEST, OTC Drug Facts 'Ask a doctor' and 'Stop use' warnings (same label)","quote":"Ask a doctor before use if you have heart disease, high blood pressure, thyroid disease, diabetes, trouble urinating due to an enlarged prostate gland … Stop use and ask a doctor if nervousness, dizziness, or sleeplessness occur","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}