{"ok":true,"entry":{"slug":"propranolol","kind":"medication","name":"propranolol","aliases":["Inderal"],"brands_sg":["Apo-Propranolol","Propanol","Inpanol"],"class":"beta blocker","tags":["heart-bp"],"use_for":"healthhub: high blood pressure, angina, irregular heartbeat","use_after":"long-term use · healthhub: not stopped suddenly after weeks","use_duration":null,"take_with":"healthhub: with or after food","pros":["healthhub lists bp, angina, migraine and tremor uses","10 mg and 40 mg tablets registered in sg","us label: dose is individualised to response"],"cons":["dizziness, cold hands and feet and tiredness are common","us label: contraindicated in bronchial asthma","healthhub: it can mask low-blood-sugar warning signs"],"dose_note":"no singapore product insert with a dosing section exists for any of the five registered propranolol tablets, so the maximum quoted here is the us propranolol hydrochloride tablets label, which sets a different ceiling for each use: in hypertension \"the usual maintenance dosage is 120 mg to 240 mg per day. In some instances a dosage of 640 mg a day may be required\"; in angina \"total daily doses of 80 mg to 320 mg\"; after myocardial infarction \"the effectiveness and safety of daily dosages greater than 240 mg for prevention of cardiac mortality have not been established\"; and in migraine \"the usual effective dose range is 160 mg to 240 mg per day\" — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["asthma or other breathing problems — healthhub: it may worsen or cause an asthma attack, and the us label makes bronchial asthma a contraindication","pre-diabetes or diabetes — healthhub: it may hide symptoms of low blood sugar such as a fast heartbeat or tremors","cardiogenic shock, sinus bradycardia or heart block greater than first degree — us label contraindications","pregnant, planning pregnancy or breastfeeding — healthhub asks that this be declared before starting"],"clashes":[{"src":["nhs_propranolol_int"],"note":"nhs: the combination with propranolol can sometimes lower blood pressure too much","with":"other blood pressure medicines"},{"src":["nhs_propranolol_int"],"note":"nhs lists these among medicines that may affect the way propranolol works","with":"heart-rhythm medicines such as amiodarone, digoxin or flecainide"},{"src":["nhs_propranolol_int"],"note":"nhs: propranolol may make it harder to recognise the warning signs of low blood sugar","with":"diabetes medicines, particularly insulin"},{"src":["nhs_propranolol_int2"],"note":"nhs: these medicines may increase blood pressure","with":"nsaids such as ibuprofen, diclofenac or naproxen"},{"src":["nhs_propranolol_int2"],"note":"nhs lists nose or sinus congestion remedies and allergy medicines among those to declare","with":"decongestants, cold remedies and allergy medicines (ephedrine, adrenaline)"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 27 Aug 2026","quote":"APO-PROPRANOLOL TABLET 10 mg SIN00046P; APO-PROPRANOLOL 40 mg SIN00041P; PROPANOL 10 mg SIN00094P; INPANOL TABLETS 10 mg SIN00076P; PROPANOL 40 mg SIN01621P | PROPRANOLOL HCl | Prescription Only | C07AA05 — all 5 propranolol rows","accessed":"2026-08-27"},{"id":"ndf_propranolol","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin00046p/","label":"MOH National Drug Formulary (Singapore) — APO-PROPRANOLOL TABLET 10 MG [SIN00046P], product information","quote":"PROPRANOLOL HCL - 10 MG … Registration Number SIN00046P … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code C07AA05 … Prescription-only Medicines with Exemptions for Supply without Prescription NA","accessed":"2026-08-27"},{"id":"healthhub_propranolol","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/propranolol","label":"HealthHub (MOH Singapore) — Propranolol, medication information leaflet","quote":"Propranolol belongs to a group of medications known as beta-blockers … High blood pressure … Irregular heartbeat … Angina … Migraine … You should take this medication with or after food","accessed":"2026-08-27"},{"id":"healthhub_propranolol_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/propranolol","label":"HealthHub (MOH Singapore) — Propranolol, precautions","quote":"You have asthma or other breathing problems – this medication may worsen or cause an asthma attack. You have pre-diabetes or diabetes - this medication may hide symptoms of low blood sugar such as fast heartbeat or tremors","accessed":"2026-08-27"},{"id":"healthhub_propranolol_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/propranolol","label":"HealthHub (MOH Singapore) — Propranolol, common side effects","quote":"Dizziness and lightheadedness … Coldness, numbness or tingling sensation of your fingers or toes … Feeling weak and tired, and that your heart beats slower … Shortness of breath","accessed":"2026-08-27"},{"id":"fda_propranolol_general","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22PROPRANOLOL+HYDROCHLORIDE%22&limit=20","label":"Propranolol Hydrochloride Tablets USP — US prescribing information (Endo USA, Inc., SPL set id 0d74bb04-8227-4afa-b523-ce1556150e07), Dosage and Administration: General","quote":"Because of the variable bioavailability of propranolol, the dose should be individualized based on response","accessed":"2026-08-27"},{"id":"fda_propranolol_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22PROPRANOLOL+HYDROCHLORIDE%22&limit=20","label":"Propranolol Hydrochloride Tablets USP — US prescribing information (Endo USA, Inc.), Dosage and Administration: hypertension and angina","quote":"The usual maintenance dosage is 120 mg to 240 mg per day. In some instances a dosage of 640 mg a day may be required … Angina Pectoris Total daily doses of 80 mg to 320 mg","accessed":"2026-08-27"},{"id":"fda_propranolol_dose2","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22PROPRANOLOL+HYDROCHLORIDE%22&limit=20","label":"Propranolol Hydrochloride Tablets USP — US prescribing information (Endo USA, Inc.), Dosage and Administration: myocardial infarction and migraine","quote":"The effectiveness and safety of daily dosages greater than 240 mg for prevention of cardiac mortality have not been established … Migraine … The usual effective dose range is 160 mg to 240 mg per day","accessed":"2026-08-27"},{"id":"fda_propranolol_ci","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22PROPRANOLOL+HYDROCHLORIDE%22&limit=20","label":"Propranolol Hydrochloride Tablets USP — US prescribing information (Endo USA, Inc.), Contraindications","quote":"Propranolol is contraindicated in 1) cardiogenic shock; 2) sinus bradycardia and greater than first degree block; 3) bronchial asthma; and 4) in patients with known hypersensitivity to propranolol hydrochloride","accessed":"2026-08-27"},{"id":"fda_inderal_la","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22INDERAL%22&limit=5","label":"Inderal LA (propranolol hydrochloride) extended-release capsules — US prescribing information, openFDA drug label record","quote":"brand_name: INDERAL LA … generic_name: PROPRANOLOL HYDROCHLORIDE … Inderal LA provides propranolol hydrochloride in a sustained-release capsule for administration once daily","accessed":"2026-08-27"},{"id":"nhs_propranolol_int","url":"https://www.nhs.uk/medicines/propranolol/taking-propranolol-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Propranolol, cautions with other medicines","quote":"other medicines for high blood pressure. The combination with propranolol can sometimes lower your blood pressure too much … other medicines for an irregular heartbeat such as amiodarone, digoxin or flecainide","accessed":"2026-08-27"},{"id":"nhs_propranolol_int2","url":"https://www.nhs.uk/medicines/propranolol/taking-propranolol-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Propranolol, further cautions with other medicines","quote":"medicines to treat nose or sinus congestion, or other cold remedies … medicines for allergies, such as ephedrine, noradrenaline or adrenaline … NSAIDs, such as ibuprofen, diclofenac or naproxen – these medicines may increase your blood pressure","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}