{"ok":true,"entry":{"slug":"prednisone","kind":"medication","name":"prednisone","aliases":["Deltasone"],"brands_sg":["Apo-Prednisone"],"class":"corticosteroid","tags":["other"],"use_for":"inflammatory, allergic and autoimmune conditions (us label)","use_after":"us label: the dose is individualised to the condition","use_duration":null,"take_with":null,"pros":["one 5 mg strength registered in sg (apo-prednisone)","us label: spans many inflammatory and allergic uses"],"cons":["us label: infection risk rises as the dose rises","us label: mood, sleep and blood-sugar changes listed","us label: adrenal suppression can persist for months"],"dose_note":"the sg register lists apo-prednisone tablet 5 mg (sin04379p) but its ndf page carries no posology section, so no singapore label maximum is published for it; the us fda label for prednisone tablets states \"The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated\" and adds that \"DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED\" — that is a stated initial range, not a fixed daily ceiling; as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["a systemic fungal infection — a us label contraindication","latent tuberculosis, or exposure to chickenpox, measles or hepatitis b — us label: reactivation or a severe course is flagged","peptic ulcer, ulcerative colitis, high blood pressure, osteoporosis, kidney impairment or myasthenia gravis — us label: caution","existing emotional instability or psychotic tendencies — us label: these may be aggravated by corticosteroids"],"clashes":[{"src":["dailymed_prednisone_int"],"note":"us label: smallpox vaccination is not to be given during corticosteroid therapy, and other immunisation procedures should not be undertaken, especially on high dose","with":"vaccines and other immunisation procedures"},{"src":["dailymed_prednisone_cyclo"],"note":"us label: convulsions reported with concurrent methylprednisolone and cyclosporine, with mutual inhibition of metabolism","with":"ciclosporin (cyclosporine)"},{"src":["dailymed_prednisone_int"],"note":"us label: aspirin should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia","with":"aspirin"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally, 27 Aug 2026","quote":"APO-PREDNISONE TABLET 5 mg SIN04379P | PREDNISONE | Prescription Only | H02AB07 | TABLET | approved 3/5/1990 — the ONLY prednisone row among all 5,511; no DELTASONE row exists; 6 PREDNISOLONE rows are a different active","accessed":"2026-08-27"},{"id":"ndf_apo_prednisone","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin04379p/","label":"MOH National Drug Formulary (Singapore) — APO-PREDNISONE TABLET 5 MG [SIN04379P], product information and forensic classification","quote":"PREDNISONE - 5 MG … Manufacturer APOTEX INC - CANADA … Licence Holder PHARMAFORTE SINGAPORE PTE LTD … Forensic Classification PRESCRIPTION ONLY MEDICINES … ATC code H02AB07 … Prescription-only Medicines with Exemptions for Supply without Prescription: NA","accessed":"2026-08-27"},{"id":"dailymed_prednisone_ind","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c60a07f9-ed9f-4434-a69d-2e2fea4843fd","label":"US FDA label via DailyMed — Prednisone Tablets, USP, INDICATIONS & USAGE (SPL setid c60a07f9…)","quote":"Prednisone Tablets, USP are indicated in the following conditions: Endocrine Disorders … Rheumatic Disorders … Collagen Diseases … Dermatologic Diseases … Allergic States: Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment … Respiratory Diseases","accessed":"2026-08-27"},{"id":"dailymed_prednisone_dose","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c60a07f9-ed9f-4434-a69d-2e2fea4843fd","label":"US FDA label via DailyMed — Prednisone Tablets, USP, DOSAGE & ADMINISTRATION","quote":"The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated … IT SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED","accessed":"2026-08-27"},{"id":"dailymed_prednisone_warn","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c60a07f9-ed9f-4434-a69d-2e2fea4843fd","label":"US FDA label via DailyMed — Prednisone Tablets, USP, CONTRAINDICATIONS and WARNINGS","quote":"Prednisone Tablets are contraindicated in systemic fungal infections and known hypersensitivity to components … Corticosteroids, including prednisone, suppress the immune system and increase the risk of infection … The rate of infectious complications increases with increasing corticosteroid dosages","accessed":"2026-08-27"},{"id":"dailymed_prednisone_prec","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c60a07f9-ed9f-4434-a69d-2e2fea4843fd","label":"US FDA label via DailyMed — Prednisone Tablets, USP, PRECAUTIONS","quote":"Psychic derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression, to frank psychotic manifestations … Drug-induced secondary adrenocortical insufficiency … may persist for months after discontinuation of therapy","accessed":"2026-08-27"},{"id":"dailymed_prednisone_int","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c60a07f9-ed9f-4434-a69d-2e2fea4843fd","label":"US FDA label via DailyMed — Prednisone Tablets, USP, immunisation and aspirin cautions","quote":"While on corticosteroid therapy patients should not be vaccinated against smallpox. Other immunization procedures should not be undertaken in patients who are on corticosteroids … Aspirin should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia","accessed":"2026-08-27"},{"id":"dailymed_prednisone_cyclo","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c60a07f9-ed9f-4434-a69d-2e2fea4843fd","label":"US FDA label via DailyMed — Prednisone Tablets, USP, corticosteroid–cyclosporine interaction","quote":"Convulsions have been reported with concurrent use of methylprednisolone and cyclosporine. Since concurrent use of these agents results in a mutual inhibition of metabolism … adverse events … may be more apt to occur","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}