{"ok":true,"entry":{"slug":"prednisolone","kind":"medication","name":"prednisolone","aliases":["Deltacortril"],"brands_sg":["Dhasolone","Xepasone","YSP Prednisolone","Prelone"],"class":"corticosteroid","tags":["respiratory","allergy","skin"],"use_for":"inflammation, allergies, asthma, skin and immune conditions","use_after":"usually once a day with breakfast · morning dosing (nhs)","use_duration":null,"take_with":"food · healthhub: with or after food, to prevent upset","pros":["nhs: calms swelling and an overactive immune system","healthhub: used for asthma, eczema, lupus and arthritis","nhs: a short course may be just up to 1 week"],"cons":["nhs: weight gain, indigestion and sleep problems","nhs: dangerous to stop suddenly after a long course","healthhub: infections catch on more easily"],"dose_note":"the us prednisone label (spl eff. 20 aug 2026) states 'the initial dosage of prednisone may vary from 5 mg to 60 mg of prednisone per day depending on the specific disease entity being treated'. nhs puts the same ceiling on prednisolone — 'the usual dose varies between 5mg and 60mg daily but occasionally higher doses may be prescribed' — so 60 mg is a usual ceiling, not an absolute maximum, and both labels emphasise the dose is individualised. sg tablets on the register run 1 mg, 5 mg and 20 mg. the doctor sets the dose and any tapering.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["an infection, tb, or recent chickenpox contact (nhs, healthhub)","diabetes, high blood pressure or stomach ulcer (nhs, healthhub)","past mental health problems, or in the family — nhs: mood changes rise with dose","vaccinations planned — healthhub: tell your healthcare professional"],"clashes":[{"src":["nhs_pred_inter"],"note":"nhs: named as affecting how prednisolone works or raising side-effect risk","with":"ibuprofen, aspirin and other anti-inflammatory painkillers"},{"src":["hh_pred_avoid"],"food":true,"note":"healthhub: raises the chance of an upset stomach","with":"alcohol"},{"src":["hh_pred_precaution"],"note":"healthhub: tell the healthcare professional before any vaccination","with":"vaccinations"},{"src":["nhs_pred_enteric"],"note":"nhs: not within 2 hours before or after","with":"indigestion medicines (with enteric-coated or gastro-resistant tablets)"},{"src":["nhs_pred_inter"],"note":"nhs: very little information — not possible to call them safe with prednisolone","with":"herbal remedies and supplements"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, full CSV pulled once via the datastore_search API and filtered locally)","quote":"Forensicclassification = 'Prescription Only' for all oral prednisolone rows: SIN04207P DHASOLONE, SIN04190P XEPASONE, SIN07771P YSP PREDNISOLONE, SIN04845P PRELONE SYRUP, SIN04237P/SIN05149P/SIN07628P PREDNISOLONE TABLET 1/5/20 mg; SIN04379P APO-PREDNISONE (prednisone) also 'Prescription Only'","accessed":"2026-08-27"},{"id":"nhs_pred_about","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone tablets and liquid: about it (page dateModified 20 Aug 2026; UK brands Deltacortril, Deltastab, Dilacort, Pevanti)","quote":"Prednisolone is a medicine used to treat a wide range of health problems including allergies, blood disorders, skin diseases, inflammation, infections and certain cancers … Prednisolone is available only on prescription as tablets and as a liquid you swallow.","accessed":"2026-08-27"},{"id":"nhs_pred_dose","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: dosage","quote":"The usual dose varies between 5mg and 60mg daily but occasionally higher doses may be prescribed. The strength of tablets range from 1mg to 25mg.","accessed":"2026-08-27"},{"id":"nhs_pred_how","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: how to take it","quote":"it's best to take prednisolone as a single dose once a day, with breakfast … Take prednisolone with breakfast so it does not upset your stomach. Taking prednisolone in the morning also means it's less likely to affect your sleep.","accessed":"2026-08-27"},{"id":"nhs_pred_stop","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: how long to take it for, stopping","quote":"It can be dangerous to stop taking prednisolone suddenly, especially if you have been on a high dose for a long time … You may only need a short course of prednisolone for up to 1 week.","accessed":"2026-08-27"},{"id":"nhs_pred_side","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: side effects, including long-term use and mood","quote":"Side effects of prednisolone include weight gain and indigestion … Taking prednisolone for a long time can lead to side effects such as: thinner bones (osteoporosis) · poorly controlled diabetes · eyesight problems · high blood pressure","accessed":"2026-08-27"},{"id":"nhs_pred_who","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: who can and cannot take it","quote":"tell your doctor or pharmacist before taking it if you: have an infection (including eye infections) or any unhealed wounds · have recently been in contact with someone with shingles, chickenpox or measles · have diabetes · have epilepsy","accessed":"2026-08-27"},{"id":"nhs_pred_mood","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: mental health history and mood changes","quote":"have ever had or any close family members have had mental health problems … The higher the dose, the more intense the mood changes can be.","accessed":"2026-08-27"},{"id":"nhs_pred_inter","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: taking it with other medicines and herbal supplements","quote":"There are many medicines that can affect the way prednisolone works, or increase the risk of side effects … This includes anti-inflammatory painkillers such as ibuprofen and aspirin … not possible to say that herbal remedies and supplements are safe","accessed":"2026-08-27"},{"id":"nhs_pred_enteric","url":"https://www.nhs.uk/medicines/prednisolone/","label":"NHS Medicines A-Z — Prednisolone: enteric-coated and gastro-resistant tablets","quote":"If your prednisolone tablets are labelled as 'enteric coated' or 'gastro resistant' … Do not take indigestion medicines 2 hours before or after taking enteric coated or gastro resistant tablets.","accessed":"2026-08-27"},{"id":"hh_prednisolone","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prednisolone","label":"HealthHub (MOH Singapore / Pharmaceutical Society of Singapore) — Prednisolone medication information leaflet, last reviewed 8 May 2026","quote":"Prednisolone belongs to a class of medicines called corticosteroids … Prednisolone can help reduce inflammation and reduce symptoms of swelling, redness, and itchiness … Take this medication with or after food to prevent stomach upset.","accessed":"2026-08-27"},{"id":"hh_pred_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prednisolone","label":"HealthHub — Prednisolone leaflet: conditions it is used for","quote":"Prednisolone can also be used to treat conditions such as: Asthma · Allergic conditions · Skin problems such as eczema, psoriasis … diseases affecting the immune system such as Lupus · Joint problems such as rheumatoid arthritis … gout","accessed":"2026-08-27"},{"id":"hh_pred_infect","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prednisolone","label":"HealthHub — Prednisolone leaflet: infection risk","quote":"You may get infections more easily while being treated with this medication. Avoid crowded places or being near people who are sick. Avoid close contact with people who have chicken pox, shingles or measles.","accessed":"2026-08-27"},{"id":"hh_pred_precaution","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prednisolone","label":"HealthHub — Prednisolone leaflet: precautions before starting","quote":"Inform your healthcare professional if … You have any of the following conditions Tuberculosis or other infections · Stomach ulcer · Severe depression · Diabetes · High blood pressure … You are planning to receive any vaccinations","accessed":"2026-08-27"},{"id":"hh_pred_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/prednisolone","label":"HealthHub — Prednisolone leaflet: food and drink to avoid","quote":"Avoid taking alcohol with this medication to reduce the chance of an upset stomach … If your doctor has put you on a low salt diet, follow this dietary instruction strictly … to prevent excessive water retention.","accessed":"2026-08-27"},{"id":"fda_prednisone","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=02158832-550b-4855-a5c5-6abbf13ed6f0","label":"FDA DailyMed — Prednisone tablets USP (Preferred Pharmaceuticals Inc.), SPL v1, effective 20 Aug 2026: Dosage and Administration","quote":"The initial dosage of prednisone may vary from 5 mg to 60 mg of prednisone per day depending on the specific disease entity being treated … IT SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:29.426925+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}