{"ok":true,"entry":{"slug":"panadol-extra","kind":"medication","name":"panadol extra","aliases":["paracetamol 500 mg + caffeine 65 mg","Panadol Extra Optizorb"],"brands_sg":["Panadol Extra","Panadol Extra with Optizorb","Panadol Extra Effervescent","Guardian Pain Relief Extra","Watsons Pain Relief Extra"],"class":"paracetamol + caffeine combination","tags":["pain-fever"],"use_for":"stronger pain — bad headache, backache, toothache","use_after":"label: every 4–6 h as required · at least 4 h apart","use_duration":null,"take_with":"with or without food (nhs, on the paracetamol half)","pros":["general sale list in sg — sold beyond pharmacies","500 mg paracetamol plus 65 mg caffeine per caplet","store-brand versions exist at the same 500/65 strength"],"cons":["other cold/flu products also contain paracetamol","each caplet also carries 65 mg caffeine","sg label: 3 days max without asking a doctor"],"dose_note":"sg panadol extra caplet label (sin09110p): 'Do not take more than 8 caplets in 24 hours' and 'Do not take more than 3 days without asking your doctors'; the Optizorb caplet (sin14766p) gives '1–2 caplets taken every 4 to 6 hours as required … Do not exceed the stated dose and do not take more frequently than every 4 hours'; nhs for plain paracetamol 500 mg: 'do not take more than 8 tablets or capsules in 24 hours' — as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"general-sale","cautions":["allergic to paracetamol, caffeine or any other ingredient — sg label: do not use","a kidney or liver condition, or dependent on alcohol / binge drinking — nhs: may not be suitable","already on a cold and flu remedy — nhs: avoid paracetamol alongside other paracetamol-containing medicines","already on warfarin or another medicine to prevent blood clots — nhs lists it as one that may not mix well"],"clashes":[{"src":["nhs_paracetamol_int"],"note":"nhs: avoid taking paracetamol at the same time as other medicines containing paracetamol","with":"other paracetamol-containing medicines (cold & flu remedies)"},{"src":["nhs_paracetamol_int"],"note":"nhs lists these among medicines that may not mix well with paracetamol","with":"warfarin and other medicines to help prevent blood clots"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, Health Sciences Authority), Forensicclassification column; all 5,511 rows pulled via the datastore_search API on 27 Aug 2026","quote":"PANADOL EXTRA CAPLET | SIN09110P | General Sale List; PANADOL EXTRA WITH OPTIZORB CAPLETS | SIN14766P | GSL; PANADOL EXTRA EFFERVESCENT | SIN14833P | GSL; GUARDIAN and WATSONS PAIN RELIEF EXTRA CAPLET 500MG/65MG | SIN16261P, SIN16263P | GSL.","accessed":"2026-08-27"},{"id":"ndf_panadol_extra","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09110p/","label":"MOH National Drug Formulary (Singapore) — PANADOL EXTRA CAPLET [SIN09110P], paracetamol 500 mg + caffeine 65 mg, Haleon Singapore Pte. Ltd.","quote":"GENERAL SALE LIST … For extra relief from stronger pain, bad headache, backache, joint pain and toothache … Do not take more than 8 caplets in 24 hours … Do not take more than 3 days without asking your doctors","accessed":"2026-08-27"},{"id":"ndf_panadol_optizorb","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14766p/","label":"MOH National Drug Formulary (Singapore) — PANADOL EXTRA WITH OPTIZORB CAPLETS 500mg/65mg [SIN14766P], Haleon Singapore Pte. Ltd.","quote":"Paracetamol 500 mg/caplet … Caffeine 65 mg/caplet … GENERAL SALE LIST … 1–2 caplets taken every 4 to 6 hours as required … Do not exceed the stated dose and do not take more frequently than every 4 hours","accessed":"2026-08-27"},{"id":"nhs_paracetamol_how","url":"https://www.nhs.uk/medicines/paracetamol-for-adults/","label":"NHS medicines A–Z — Paracetamol for adults (how and when to take it)","quote":"You can take tablets or capsules with or without food … leave at least 4 hours between each dose … do not take more than 8 tablets or capsules in 24 hours","accessed":"2026-08-27"},{"id":"nhs_paracetamol_int","url":"https://www.nhs.uk/medicines/paracetamol-for-adults/","label":"NHS medicines A–Z — Paracetamol for adults (who it is not suitable for, and medicines that may not mix well)","quote":"avoid taking paracetamol … as other medicines containing paracetamol, for example, cold and flu remedies … medicines to help prevent blood clots, such as warfarin … a kidney or liver condition, you're dependent on alcohol or binge drink","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:27.496708+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}