{"ok":true,"entry":{"slug":"oxybutynin","kind":"medication","name":"oxybutynin","aliases":["Ditropan"],"brands_sg":["Obutin"],"class":"antimuscarinic","tags":["other"],"use_for":"overactive bladder — urgency, frequency, leaking","use_after":null,"use_duration":null,"take_with":"with or without food · alcohol adds to the drowsiness","pros":["healthhub: eases urgency, leaking and frequency","healthhub: taken with or without food","5 mg tablets are the sg registered strength"],"cons":["dry mouth, dry eyes and constipation are common","drowsiness and blurred vision can affect driving","overheating in hot weather is a listed effect"],"dose_note":"no sg dosing is published for obutin, the only oxybutynin registered here, so the ceiling below is from the us label for oxybutynin chloride tablets: \"The usual dose is one 5-mg tablet two to three times a day. The maximum recommended dose is one 5-mg tablet four times a day\", with \"A lower starting dose of 2.5 mg two or three times a day … recommended for the frail elderly\" — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["not able to empty the bladder, or slow stomach emptying — healthhub precaution","uncontrolled narrow angle glaucoma — healthhub precaution","liver, kidney or heart problems — healthhub precaution","myasthenia gravis, an overactive thyroid, parkinson's disease or hiatus hernia — healthhub precaution"],"clashes":[{"src":["hh_oxybutynin_prec2"],"note":"healthhub: these combinations may affect the condition in people with dementia","with":"cholinesterase inhibitors for dementia (galantamine, donepezil, rivastigmine)"},{"src":["fda_oxybutynin_int"],"note":"us label: may increase the frequency and severity of dry mouth, constipation and drowsiness","with":"other anticholinergic medicines"},{"src":["fda_oxybutynin_int"],"note":"us label: anticholinergics may antagonise their effect","with":"metoclopramide and other prokinetics"},{"src":["fda_oxybutynin_int2"],"note":"us label: plasma levels were 3 to 4 fold higher with ketoconazole; erythromycin and clarithromycin are named too","with":"ketoconazole and other strong cyp3a4 inhibitors"},{"src":["hh_oxybutynin_food"],"food":true,"note":"healthhub: may increase the risk of dizziness, light-headedness or drowsiness","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; cached at /tmp/hsa_all.json and filtered locally, not re-fetched","quote":"OBUTIN TABLETS 5 mg [SIN11215P] | OXYBUTYNIN CHLORIDE | Prescription Only | G04BD04 | TABLET | 5 mg — the only oxybutynin row in the 5,511-row register","accessed":"2026-08-27"},{"id":"ndf_obutin","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin11215p/","label":"MOH National Drug Formulary (Singapore) — OBUTIN TABLETS 5 MG [SIN11215P], product information (no indication or dosing section is published for this product)","quote":"OBUTIN TABLETS 5 MG [SIN11215P] … OXYBUTYNIN CHLORIDE - 5 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … ATC code G04BD04 … Prescription-only Medicines with Exemptions for Supply without Prescription NA","accessed":"2026-08-27"},{"id":"hh_oxybutynin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, medication information leaflet, last reviewed 08 April 2026","quote":"Oxybutynin is used to treat a condition called overactive bladder. Overactive bladder happens when you cannot control your bladder muscle.","accessed":"2026-08-27"},{"id":"hh_oxybutynin_sym","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, symptoms it addresses","quote":"not being able to control when to empty your bladder, where you get a strong need to urinate with leaking or wetting incidence (urinary incontinence) … a strong need to urinate right away (urgency) … urinating often (frequency)","accessed":"2026-08-27"},{"id":"hh_oxybutynin_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, how to take it","quote":"Do not stop taking your medication without checking with your healthcare professional. You may take this medication with or without food.","accessed":"2026-08-27"},{"id":"hh_oxybutynin_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, common side effects","quote":"Drowsiness May affect your ability to drive and use machinery … Dizziness … Dry Mouth … Dry Eyes … Constipation … Overheating of the body … Blurred vision … Headache","accessed":"2026-08-27"},{"id":"hh_oxybutynin_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, precautions","quote":"You are not able to empty your bladder (urinary retention) … You have an eye problem called \"uncontrolled narrow angle glaucoma\" … You have liver, kidney or heart problems … myasthenia gravis … hyperthyroidism … Parkinson's disease or hiatus hernia","accessed":"2026-08-27"},{"id":"hh_oxybutynin_prec2","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, precaution on cholinesterase inhibitors","quote":"You have dementia and is taking medications called cholinesterase inhibitors such as Galantamine, Donepezil, Rivastigmine as these combinations may affect the condition.","accessed":"2026-08-27"},{"id":"hh_oxybutynin_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/oxybutynin","label":"HealthHub (MOH Singapore) — Oxybutynin, food and medication to avoid","quote":"Avoid drinking alcohol as it may increase the risk of dizziness, light-headedness or drowsiness.","accessed":"2026-08-27"},{"id":"fda_oxybutynin_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22OXYBUTYNIN+CHLORIDE%22&limit=3","label":"US FDA label — Oxybutynin Chloride tablets (A-S Medication Solutions, effective 2025-11-18), Dosage and Administration, via openFDA","quote":"Adults The usual dose is one 5-mg tablet two to three times a day. The maximum recommended dose is one 5-mg tablet four times a day.","accessed":"2026-08-27"},{"id":"fda_oxybutynin_dose2","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22OXYBUTYNIN+CHLORIDE%22&limit=3","label":"US FDA label — Oxybutynin Chloride tablets, Dosage and Administration: frail elderly, via openFDA","quote":"A lower starting dose of 2.5 mg two or three times a day is recommended for the frail elderly.","accessed":"2026-08-27"},{"id":"fda_oxybutynin_int","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22OXYBUTYNIN+CHLORIDE%22&limit=3","label":"US FDA label — Oxybutynin Chloride tablets, Drug Interactions, via openFDA","quote":"The concomitant use of oxybutynin with other anticholinergic drugs … may increase the frequency and/or severity of such effects. … Anticholinergic agents may also antagonize the effects of prokinetic agents, such as metoclopramide.","accessed":"2026-08-27"},{"id":"fda_oxybutynin_int2","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22OXYBUTYNIN+CHLORIDE%22&limit=3","label":"US FDA label — Oxybutynin Chloride tablets, Drug Interactions: CYP3A4 inhibitors, via openFDA","quote":"Mean oxybutynin chloride plasma concentrations were approximately 3 to 4 fold higher when oxybutynin chloride was administered with ketoconazole, a potent CYP3A4 inhibitor. Other inhibitors … macrolide antibiotics (e.g., erythromycin and clarithromycin), may alter oxybutynin mean pharmacokinetic parameters","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:27.496708+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}