{"ok":true,"entry":{"slug":"omega-7","kind":"supplement","name":"omega-7","aliases":["palmitoleic acid","sea buckthorn oil"],"brands_sg":["SeaBuckWonders","Life Extension","Terry Naturally","Sibu Beauty","Source Naturals"],"class":"fatty acid","tags":["skin-hair","heart"],"use_for":"palmitoleic acid oil · human benefits stay unproven","use_after":null,"use_duration":null,"take_with":null,"pros":["poa-rich foods improved ldl replacing saturated fat","algal omega-7 oil tested highest for palmitoleic acid"],"cons":["purified poa trials were largely neutral on lipids","products range from 0.2% to 35.5% palmitoleic acid","clinically meaningful benefits remain unproven"],"dose_note":"a 2026 review concludes that benefits of purified palmitoleic acid supplementation remain unproven; a 2026 product analysis found commercial omega-7 products are not compositionally equivalent, so label amounts are not comparable between brands","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["limited human evidence — benefits are not established","sea buckthorn products differ widely in omega-7 content"],"clashes":[],"sources":[{"id":"poa_review","url":"https://europepmc.org/article/PMC/PMC13230081","label":"Palmitoleic (16:1 n-7) acid and metabolic health: integrating observational, clinical, and mechanistic evidence (Front Nutr 2026)","quote":"POA-rich food matrices such as macadamia-based diets can improve LDL-cholesterol … short-term trials of purified POA supplementation have largely reported neutral effects … clinically meaningful benefits of purified POA supplementation remain unproven","accessed":"2026-08-27"},{"id":"omega7_products","url":"https://europepmc.org/article/MED/42459804","label":"Palmitoleic acid content and composition-based nutritional quality of commercial omega-7 oils and supplements (Front Nutr 2026)","quote":"Commercial omega-7 products vary widely in fatty acid composition … The algal oil showed the highest POA (67.3%) … SBO supplements showed the greatest variability, ranging from omega-7-rich oils (25.5-35.5% POA) to supplements with low or trace omega-7 (0.2-8.3% POA)","accessed":"2026-08-27"},{"id":"hsa_pr","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/omega-7","label":"iHerb Singapore — Omega-7: Sea Buckthorn & Palmitoleic Acid Softgels category page","quote":"Omega-7: Sea Buckthorn & Palmitoleic Acid Softgels","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:27.496708+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}