{"ok":true,"entry":{"slug":"mycophenolate","kind":"medication","name":"mycophenolate","aliases":["mycophenolate mofetil","CellCept","Myfortic"],"brands_sg":["CellCept","Myfortic","Myfenax","Mycofit","Mofecon"],"class":"antiproliferative immunosuppressant","tags":["other"],"use_for":"healthhub: stopping rejection of a transplanted organ","use_after":"healthhub: mofetil half to one hour before food","use_duration":null,"take_with":"healthhub: water · antacids or magnesium 2 hours apart","pros":["healthhub: also used in autoimmune disease","sg label: 1 g twice a day is the standard renal dose","register: capsules, tablets, gastro-resistant tablets"],"cons":["healthhub: birth defects and miscarriage in pregnancy","healthhub: diarrhoea, nausea, headache, raised bp","healthhub: long-term use raises skin cancer risk"],"dose_note":"the singapore product information for cellcept (national drug formulary) states “A dose of 1 g administered orally or intravenously (over NO LESS THAN 2 HOURS) twice a day (daily dose of 2 g) is recommended for use in renal transplant patients”, and “A dose of 1.5g … twice a day (daily dose of 3g) is recommended for use in cardiac transplant patients” — 3 g a day is the highest daily figure the sg cellcept label carries, and the label notes patients on 2 g/day showed “an overall better safety profile” than those on 3 g/day. the enteric-coated salt is a different product: myfortic's sg label sets “720 mg … twice daily (1440 mg daily dose)” and says the two forms should not be swapped without physician supervision. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["pregnancy — an sg label contraindication; it can cause miscarriage and birth defects","women of childbearing potential without highly effective contraception — sg label contraindication","breastfeeding — an sg label contraindication; healthhub adds 6 weeks after stopping","cancer, kidney or liver disease, gastric ulcers, diabetes or infection (healthhub)"],"clashes":[{"src":["hh_myc_avoid"],"note":"healthhub lists these among medicines that may interact","with":"cholestyramine, antivirals, antibiotics and other immunosuppressants"},{"src":["hh_myc_avoid","hh_myc_prec"],"note":"healthhub: effectiveness may drop, so a barrier method is added","with":"hormonal contraceptives (the pill)"},{"src":["hh_myc_avoid"],"note":"healthhub: these are taken at least 2 hours after mycophenolate","with":"antacids and magnesium supplements"},{"src":["hh_myc_avoid"],"food":true,"note":"healthhub: it can increase drowsiness or dizziness from the medicine","with":"alcohol"},{"src":["hh_myc_prec"],"note":"healthhub: it may raise infection chance or make a vaccine less effective","with":"live or inactivated vaccines"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084); cached at /tmp/hsa_all.json and filtered locally (not re-fetched), 19 mycophenolate rows","quote":"CELLCEPT TABLET 500 mg SIN10032P · MYFORTIC GASTRO-RESISTANT TABLET 360 mg SIN12377P · MYFENAX FILM-COATED TABLETS 500MG SIN13986P · MYCOFIT 250 SIN15596P · MOFECON 500 SIN16010P — all 19 rows “Prescription Only”, ATC L04AA06","accessed":"2026-08-27"},{"id":"hh_myc_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/mycophenolate","label":"HealthHub (Pharmaceutical Society of Singapore / MOH) — Mycophenolate: what is this medication for","quote":"Mycophenolate belongs to a group of medications known as immunosuppressive agents. It is used to prevent your body from rejecting a transplanted organ. This medication can also be used to treat autoimmune diseases","accessed":"2026-08-27"},{"id":"hh_myc_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/mycophenolate","label":"HealthHub — Mycophenolate: how should I take or use this medication","quote":"Mycophenolate mofetil: Take this medication half to one hour before food. Mycophenolate sodium EC tablet: May be taken with or without food. Do not chew, crush, or open the capsules/tablets.","accessed":"2026-08-27"},{"id":"hh_myc_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/mycophenolate","label":"HealthHub — Mycophenolate: what precautions should I take","quote":"Mycophenolate has been reported to be able to cause harm to the foetus when taken during pregnancy (miscarriages and birth defects) … Mycophenolate may decrease the effectiveness of birth control pills","accessed":"2026-08-27"},{"id":"hh_myc_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/mycophenolate","label":"HealthHub — Mycophenolate: common side effects","quote":"Diarrhoea, constipation, nausea, vomiting, or stomach pain … Dizziness, drowsiness … Headache, difficulty sleeping (insomnia) … Increase in blood pressure … Swelling and growth of the gums","accessed":"2026-08-27"},{"id":"hh_myc_cancer","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/mycophenolate","label":"HealthHub — Mycophenolate: rare but serious side effects","quote":"For patients who are on long-term mycophenolate, there is also an increased chance of skin cancer and lymphoma.","accessed":"2026-08-27"},{"id":"hh_myc_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/mycophenolate","label":"HealthHub — Mycophenolate: what food or medication should I avoid","quote":"Medications that may interact with mycophenolate include cholestyramine, antivirals, antibiotics, immunosuppressive medications, and hormonal contraceptives. Take indigestion remedies (antacids) or magnesium supplements at least 2 hours after taking mycophenolate.","accessed":"2026-08-27"},{"id":"ndf_myc_renal","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin10032p/","label":"Singapore National Drug Formulary — CELLCEPT TABLET 500 mg [SIN10032P], Dosage and Administration (renal)","quote":"A dose of 1 g administered orally or intravenously (over NO LESS THAN 2 HOURS) twice a day (daily dose of 2 g) is recommended for use in renal transplant patients.","accessed":"2026-08-27"},{"id":"ndf_myc_cardiac","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin10032p/","label":"Singapore National Drug Formulary — CELLCEPT [SIN10032P], Dosage and Administration (cardiac)","quote":"A dose of 1.5g administered orally or intravenously (over NO LESS THAN 2 HOURS) twice a day (daily dose of 3g) is recommended for use in cardiac transplant patients.","accessed":"2026-08-27"},{"id":"ndf_myc_myfortic","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12377p/","label":"Singapore National Drug Formulary — MYFORTIC GASTRO-RESISTANT TABLET 360 mg [SIN12377P], Dosage regimen","quote":"The recommended dose is 720 mg (four 180 mg or two 360 mg Myfortic gastro-resistant tablets) twice daily (1440 mg daily dose).","accessed":"2026-08-27"},{"id":"ndf_myc_contra","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin10032p/","label":"Singapore National Drug Formulary — CELLCEPT [SIN10032P], Contraindications","quote":"CellCept is contraindicated during pregnancy due to its mutagenic and teratogenic potential … contraindicated in women of childbearing potential not using highly effective contraceptive methods … contraindicated in women who are breastfeeding","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:26.600885+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}